Results 131 to 140 of about 10,826 (180)

Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap

Biology Open, 2015
In addition to its role in the endogenous synthesis of cysteine, cystathionine gamma-lyase (CGL) is a major physiological source of the vasorelaxant hydrogen sulfide.
Hua Jiang, K. Joseph Hurt, Kelsey Breen, Sally P. Stabler, Robert H. Allen, David J. Orlicky, Kenneth N. Maclean   +6 more
doaj   +1 more source

Differential effects of EPA vs. DHA on postprandial vascular function and the plasma oxylipin profile in men [PDF]

, 2016
Our objective was to investigate the impact of EPA versus DHA, on arterial stiffness and reactivity, and underlying mechanisms (with a focus on plasma oxylipins), in the postprandial state.
Aedin Cassidy, Anne Marie Minihane, Armah, Asmar, Balakumar, Berry, Bonetti, Chong, Conquer, David Vauzour, Feelisch, Fischer, Flammer, Frömel, Hallund, Hickson, Huang, Ingrid Fleming, Jackson, Janner, Janner, Khader Awwad, Lauer, Lind, Lithander, Macready, Martin, Michaelis, Miller, Mitchell, Moerland, Mori, Morin, Morin, Mozaffarian, Mozaffarian, Mustafa, Neil Rigby, Noemi Tejera, Nürnberger, Pase, Psychogios, Pucci, Purcell, Ras, Rontoyanni, Ruiz-Lopez, Salem, Saravanan, Schebb, Schächinger, Seán McManus, Shearer, Shearer, Shen, Siasos, Strassburg, Vauzour, Vlachopoulos, Wang, Wang, West, Wilson, Ye   +63 more
core   +1 more source

Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis [PDF]

, 2019
Hydrogen sulfide (H2S), generated by cystathionine γ lyase (CSE), is an important endogenous regulator of vascular function. The aim of the present study was to investigate the control and consequences of CSE activity in endothelial cells under ...
Bibli, Sofia-Iris, Brandes, Ralf P., Chen, Chen, Filis, Konstantinos A., Fleming, Ingrid, Heidler, Juliana, Hu, Jiong, Kojonazarov, Baktybek, Luck, Bert, Malik, Randa Abdel, Papapetropoulos, Andreas, Pfeilschifter, Josef, Randriamboavonjy, Voahanginirina, Schürmann, Christoph, Sigala, Fragiska, Siragusa, Mauro, Siuda, Daniel, Szabo, Csaba, Tsilimigras, Diamantis I., Wang, Dao Wen, Wittig, Ilka, Wittig, Janina, Zografos, George, Zukunft, Sven   +23 more
core  

Study on Alleviation Mechanism of Hydrogen Sulfide on Copper Stress in Rice Seedlings [PDF]

, 2015
硫化氢（hydrogensulfide,H2S）是继一氧化氮（nitricoxide,NO）、一氧化碳和(carbonmonooxide,CO)之后被广泛关注的气体信号分子，低浓度的H2S在动物、植物和微生物中被证实参与了众多生理生化过程，调节了有机体的生长发育。H2S在植物应对盐害、干旱、重金属胁迫、冷热胁迫中发挥重要作用，增强植物对逆境的抵抗力。 铜污染是环境污染中不容忽视的一类重金属污染。本文中，我们以水稻（Oryzasativa）为材料，研究了H2S对铜胁迫的影响。结果显示低浓度的H2S ...
尹珊珊
core  

Hydrogen sulfide/polysulfides signaling and neuronal diseases

Neurotherapeutics
Hydrogen sulfide (H2S) and polysulfides including H2Sn (n ​= 2 or more) regulate neuronal activity, vascular tone, oxytosis/ferroptosis, oxygen sensing, cancer growth and senescence.
Hideo Kimura
doaj   +1 more source

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase

Science, 2008
Guangdong Yang, Lingyun Wu, B. Jiang, Wei Yang, J. Qi, Kun Cao, Q. Meng, A. Mustafa, W. Mu, Shengming Zhang, S. Snyder, Rui Wang   +11 more
semanticscholar   +1 more source

The effects of marginal pyridoxine deficiency and high protein intakes on vitamin b6 status and enzymes in intermediary metabolism in rats [PDF]

, 2015
Pyridoxal-5-phosphate (PLP), the active form of vitamin B6 (B6), is a co-factor for enzymes in macronutrient metabolism. Increasing protein intake may affect B6 by increasing PLP-dependent enzymes in amino acid metabolism, which may be more pronounced ...
Raposo_Blouw, Sara
core   +1 more source

Enzymes that generate and regulate intracellular persulfides and polysulfides: mechanistic insights and inhibitors

Frontiers in Physiology
Reactive sulfur species (RSS), which include various persulfides and polysulfides, are generated by multiple enzymes in vivo and play critical roles in mammalian physiological processes such as redox signaling, metabolic regulation, radical scavenging ...
Ko Hirabayashi, Eita Sasaki, Hisashi Ohno, Orie Takayama, Sota Yamada, Kenjiro Hanaoka, Kenjiro Hanaoka   +6 more
doaj   +1 more source

Comparison of the Plasma Metabolome Profiles Between the Internal Thoracic Artery and Ascending Aorta in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Gas Chromatography Time-of-Flight Mass Spectrometry. [PDF]

, 2019
BackgroundThe left internal thoracic artery (LITA) has been used as the first conduit of choice in coronary artery bypass grafting (CABG) because of excellent long-term patency and outcomes.
Cho, Joo Youn, Hwang, Ho Young, Jang, Cholsoon, Jang, In Jin, Kim, Andrew HyoungJin, Kim, Ji Seong, Kim, Ki Bong   +6 more
core  

Role of Sex and Early Life Stress Experience on Porcine Cardiac and Brain Tissue Expression of the Oxytocin and H₂S Systems

Biomolecules
Early life stress (ELS) significantly increases the risk of chronic cardiovascular diseases and may cause neuroinflammation. This post hoc study, based on the material available from a previous study showing elevated “serum brain injury markers” in male ...
Franziska Münz, Nadja Abele, Fabian Zink, Eva-Maria Wolfschmitt, Melanie Hogg, Claus Barck, Josef Anetzberger, Andrea Hoffmann, Michael Gröger, Enrico Calzia, Christiane Waller, Peter Radermacher, Tamara Merz   +12 more
doaj   +1 more source