Results 111 to 120 of about 412,162 (161)

Chromobox 3 assembles an epigenetic complex contributing to cystathionine γ-lyase-mediated protection against aortic aneurysm/dissection. [PDF]

Nat Commun
Zhao Y, Cui C, Gao H, Yao Y, Niu Y, Cheng L, Shao X, Zhang H, Wang Y, Lin Y, Dong Z, Wu H, Chen Z, Yang L, Geng B.   +14 more
europepmc   +1 more source

Dual targeting of H₂S synthesizing enzymes; cystathionine β-synthase and cystathionine γ-lyase by miR-939-5p effectively curbs triple negative breast cancer. [PDF]

Heliyon, 2023
Nafea H, Youness RA, Dawoud A, Khater N, Manie T, Abdel-Kader R, Bourquin C, Szabo C, Gad MZ.   +8 more
europepmc   +1 more source

Cystathionine γ-lyase is a major regulator of cognitive function through neurotrophin signaling and neurogenesis. [PDF]

Proc Natl Acad Sci U S A
Chakraborty S, Jamuna Tripathi S, Vázquez-Rosa E, Chaubey K, Fujioka H, Miller E, Tyagi R, Vignane T, Sharma SM, Thomas B, Weil ZM, Nelson RJ, Filipovic MR, Orsburn BC, Snyder SH, Pieper AA, Paul BD.   +16 more
europepmc   +1 more source

Hijacking the Hydrogen Sulfide Axis: A Novel 4-Trifluoromethylquinoline Derivative Suppresses Glioblastoma via Cystathionine γ-Lyase Suppression. [PDF]

J Med Chem
Luo Z, Xu G, Li C, Sun Z, Chen H, Yang M, Ye Y, Chen Q, Xu B, Luo H, Sun B.   +10 more
europepmc   +1 more source

Cystathionine γ-lyase exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation. [PDF]

JCI Insight, 2022
Latour YL, Sierra JC, Finley JL, Asim M, Barry DP, Allaman MM, Smith TM, McNamara KM, Luis PB, Schneider C, Jacobse J, Goettel JA, Calcutt MW, Rose KL, Schey KL, Milne GL, Delgado AG, Piazuelo MB, Paul BD, Snyder SH, Gobert AP, Wilson KT.   +21 more
europepmc   +1 more source

Beyond Hydrogen Sulfide and Cysteine Metabolism: Reframing Cystathionine γ-Lyase as a Potential Translational Regulator of Hypoxia-Inducible Factor-1α in Clear Cell Ovarian Carcinoma. [PDF]

Cells
El-Naggar AM.
europepmc   +1 more source

Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis. [PDF]

Redox Biol, 2022
Thanki KK, Johnson P, Higgins EJ, Maskey M, Phillips C, Dash S, Almenas FA, Govar AA, Tian B, Villéger R, Beswick E, Wang R, Szabo C, Chao C, Pinchuk IV, Hellmich MR, Módis K.   +16 more
europepmc   +1 more source

Anti-Inflammatory Effects of Alpha-Lipoic Acid Modulate Cystathionine-γ-Lyase Expression in RAW 264.7 Macrophages. [PDF]

Int J Mol Sci
Shahid A, Chambers S, Scott-Thomas A, Zawari M, Bhatia M.   +4 more
europepmc   +1 more source

Hepatocellular cystathionine γ lyase/hydrogen sulfide attenuates nonalcoholic fatty liver disease by activating farnesoid X receptor. [PDF]

Hepatology, 2022
Xu W, Cui C, Cui C, Chen Z, Zhang H, Cui Q, Xu G, Fan J, Han Y, Tang L, Targher G, Byrne CD, Zheng MH, Yang L, Cai J, Geng B.   +15 more
europepmc   +1 more source

Purification and characterization of cystathionine γ-liase from Lactobacillus fermentum DT41

, 1998
A homo-tetrameric ca. 140-kDa cystathionine y-lyase was purified to homogeneity from Luctobacillus,f~rmentum DT41 by four chromatographic steps. This was the first enzyme responsible for amino acid catabolism purified from lactobacilli.
E. SAMCCHI, GOBBETTI, Marco, Marco Gobbetti, E. SMACCHI, Emanuele Smacchi   +4 more
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