Results 131 to 140 of about 412,162 (161)

Elucidation of the stereochemical mechanism of cystathionine γ-lyase reveals how substrate specificity constrains catalysis. [PDF]

ACS Catal
Zmich A, Perkins LJ, Bingman C, Buller AR.   +3 more
europepmc   +1 more source

Cystathionine γ-lyase inhibits mitochondrial oxidative stress by releasing H₂S nearby through the AKT/NRF2 signaling pathway. [PDF]

Front Pharmacol
Xiao T, Chen S, Yan G, Zheng J, Qiu Q, Lin S, Zong Y, Chang H, Yu Chang AC, Wu Y, Hou C.   +10 more
europepmc   +1 more source

Metabolic Effects of Sodium Thiosulfate During Resuscitation from Trauma and Hemorrhage in Cigarette-Smoke-Exposed Cystathionine-γ-Lyase Knockout Mice. [PDF]

Biomedicines
Feth M, Hezel F, Gröger M, Hogg M, Zink F, Kress S, Hoffmann A, Calzia E, Wachter U, Radermacher P, Merz T.   +10 more
europepmc   +1 more source

Cystathionine γ-lyase-derived H₂S negatively regulates thymic egress via allosteric inhibition of sphingosine-1-phosphate lyase. [PDF]

Acta Pharmacol Sin
Hu YT, Liu ZW, Zhang TH, Ma YE, He L, Zhang J, Zhou YY, Vidal-Puig A, Pan DJ, Wu F.   +9 more
europepmc   +1 more source

Cystathionine-γ-lyase contributes to tamoxifen resistance, and the compound I194496 alleviates this effect by inhibiting the PPARγ/ACSL1/STAT3 signalling pathway in oestrogen receptor-positive breast cancer. [PDF]

Sci Rep
Fu H, Han X, Guo W, Zhao X, Yu C, Zhao W, Feng S, Wang J, Zhang Z, Lei K, Li M, Wang T.   +11 more
europepmc   +1 more source

Skeletal muscle cystathionine γ-lyase deficiency promotes obesity and insulin resistance and results in hyperglycemia and skeletal muscle injury upon HFD in mice. [PDF]

Redox Rep
Lu J, Tang Z, Xu M, Lu J, Wang F, Ni X, Wang C, Yu B.   +7 more
europepmc   +1 more source

USP9X-mediated REV1 deubiquitination promotes lung cancer radioresistance via the action of REV1 as a Rad18 molecular scaffold for cystathionine γ-lyase. [PDF]

J Biomed Sci
Chen Y, Feng X, Wu Z, Yang Y, Rao X, Meng R, Zhang S, Dong X, Xu S, Wu G, Jie X.   +10 more
europepmc   +1 more source

Activating transcription factor 6 alleviates secondary brain injury by increasing cystathionine γ-lyase expression in a rat model of intracerebral hemorrhage. [PDF]

Aging (Albany NY)
Liang T, Xu S, Liu R, Xia X.
europepmc   +1 more source

Cystine rather than cysteine is the preferred substrate for β-elimination by cystathionine γ-lyase: implications for dietary methionine restriction. [PDF]

Geroscience
Jeitner TM, Azcona JA, Ables GP, Cooke D, Horowitz MC, Singh P, Kelly JM, Cooper AJL.   +7 more
europepmc   +1 more source

Persulfidation of Human Cystathionine γ-Lyase Inhibits Its Activity: A Negative Feedback Regulation Mechanism for H₂S Production. [PDF]

Antioxidants (Basel)
Jia G, Li H, Gan H, Wang J, Zhu Z, Wang Y, Ye Y, Shang X, Niu W.   +8 more
europepmc   +1 more source