Results 111 to 120 of about 1,025,233 (163)

How to fix a broken protein: restoring function to mutant human cystathionine β-synthase. [PDF]

Hum Genet, 2022
Kruger WD.
europepmc   +1 more source

Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation. [PDF]

Elife, 2022
Zhu H, Chan KT, Huang X, Cerra C, Blake S, Trigos AS, Anderson D, Creek DJ, De Souza DP, Wang X, Fu C, Jana M, Sanij E, Pearson RB, Kang J.   +14 more
europepmc   +1 more source

Role of the cystathionine β-synthase / H₂S pathway in the development of cellular metabolic dysfunction and pseudohypoxia in down syndrome. [PDF]

Redox Biol, 2022
Panagaki T, Pecze L, Randi EB, Nieminen AI, Szabo C.   +4 more
europepmc   +1 more source

Involvement of cystathionine β-synthase in ATP-induced hydrogen sulfide production in cochlear outer hair cells. [PDF]

J Otol
Harada N, Ito Y, Takashima I, Ojida A, Sekiguchi F, Kawabata A.   +5 more
europepmc   +1 more source

Effect of long-term chronic hyperhomocysteinemia on retinal structure and function in the cystathionine-β-synthase mutant mouse. [PDF]

Exp Eye Res, 2022
Xiao H, Wang J, Barwick SR, Yoon Y, Smith SB.   +4 more
europepmc   +1 more source

Cystathionine β-synthase is inhibited by epinephrine and norepinephrine over-secretion via NF-κB activation in stress-induced hyperhomocysteinemia. [PDF]

Sci Rep
Zhang L, Wu S, Xie F, Wang X, Sun Z, Zhao Y, Qian L.   +6 more
europepmc   +1 more source

Loss of cystathionine-β-synthase contributes to elevated OXPHOS, a vulnerability in Ara-C-resistant Myeloid Leukemia in Down syndrome. [PDF]

Biochem Pharmacol
Thibodeau J, Zhao J, Edwards H, Polin L, Kushner J, Dzinic SH, White K, Hershberger K, Su Y, Arroum T, Pham L, Pavelich L, Awdish R, LaValley J, Boucher AC, Chen W, Li J, Bao X, Hüttemann M, Back JB, Allen JE, Prabhu VV, Crispino JD, Taub JW, Ge Y.   +24 more
europepmc   +1 more source

H₂S Prodrug, SG-1002, Protects against Myocardial Oxidative Damage and Hypertrophy In Vitro via Induction of Cystathionine β-Synthase and Antioxidant Proteins. [PDF]

Biomedicines, 2023
Islam RK, Donnelly E, Donnarumma E, Hossain F, Gardner JD, Islam KN.   +5 more
europepmc   +1 more source

Abnormal Trophoblast Invasion in Early-Onset Preeclampsia: The Involvement of Cystathionine β-Synthase, Specificity Protein 1 and microRNA-22. [PDF]

Cureus
Arora P, Kalra S, Dhingra R, Kshetrapal P, Bhatla N, Dwivedi S.   +5 more
europepmc   +1 more source

Structural insight into the unique conformation of cystathionine β-synthase from Toxoplasma gondii. [PDF]

Comput Struct Biotechnol J, 2021
Fernández-Rodríguez C, Oyenarte I, Conter C, González-Recio I, Núñez-Franco R, Gil-Pitarch C, Quintana I, Jiménez-Osés G, Dominici P, Martinez-Chantar ML, Astegno A, Martínez-Cruz LA.   +11 more
europepmc   +1 more source