Results 101 to 110 of about 1,025,233 (163)

Examination of two different proteasome inhibitors in reactivating mutant human cystathionine β-synthase in mice. [PDF]

PLoS One, 2023
Gupta S, Lee HO, Wang L, Kruger WD.
europepmc   +1 more source

Relationships Between H₂S and OT/OTR Systems in Preeclampsia

Antioxidants
Pre-eclampsia (PE) is a hypertensive pregnancy complication. Oxidative stress is hypothesized to contribute to the pathophysiology of PE. Both the hydrogen sulfide (H2S) and oxytocin (OT) systems might play a role in the pathophysiology of PE, like their
Tamara Merz, Sarah Ecker, Nicole Denoix, Oscar McCook, Stefanie Kranz, Ulrich Wachter, Edit Rottler, Thomas Papadopoulos, Christoph Fusch, Cosima Brucker, Jakob Triebel, Thomas Bertsch, Peter Radermacher, Christiane Waller   +13 more
doaj   +1 more source

Inhibition of fungal pathogenicity by targeting the H₂S-synthesizing enzyme cystathionine β-synthase. [PDF]

Sci Adv, 2022
Chang W, Zhang M, Jin X, Zhang H, Zheng H, Zheng S, Qiao Y, Yu H, Sun B, Hou X, Lou H.   +10 more
europepmc   +1 more source

Cystathionine β-synthase is required for oocyte quality by ensuring proper meiotic spindle assembly. [PDF]

Cell Prolif, 2022
Cao Y, Zhu X, Zhen P, Tian Y, Ji D, Xue K, Yan W, Chai J, Liu H, Wang W.   +9 more
europepmc   +1 more source

NO• binds human cystathionine β-synthase quickly and tightly

, 2014
The hexa-coordinate heme in the H2S-generating human enzyme cystathionine β-synthase (CBS) acts as a redox-sensitive regulator that impairs CBS activity upon binding NO· or CO at the reduced iron.
GIUFFRE', ALESSANDRO, J. B. Vicente, M. I. S. Mendes, SARTI, Paolo, P. Leandro, H. G. Colaço   +5 more
core   +1 more source

A Methionine-Portioning-Based Medical Nutrition Therapy with Relaxed Fruit and Vegetable Consumption in Patients with Pyridoxine-Nonresponsive Cystathionine-β-Synthase Deficiency. [PDF]

Nutrients, 2023
Uygur E, Aktuglu-Zeybek C, Aghalarov M, Cansever MS, Kıykım E, Zubarioglu T.   +5 more
europepmc   +1 more source

Two siblings with vitamin B6-nonresponsive cystathionine β-synthase deficiency and differing blood methionine levels during the neonatal period [PDF]

, 1997
We present two siblings with vitamin B6-nonresponsive homocystinuria due to a deficiency of cystathionine β-synthase who had different levels of methionine in the blood during the neonatal period, even though they had the same genetic defect. One of them
Naito, Etsuo, Watanabe, Toshiyuki, Ito, Michinori, マツダ, ジュンコ, Yokota, Ichiro, 1153, クロダ, ヤスヒロ, ワタナベ, トシユキ, ナイトウ, エツオ, 黒田, 弘, 60666/profile-ja.html, Kuroda, Yasuhiro, イトウ, ミチノリ, ヨコタ, イチロウ, Matsuda, Junko   +14 more
core  

Dual targeting of H₂S synthesizing enzymes; cystathionine β-synthase and cystathionine γ-lyase by miR-939-5p effectively curbs triple negative breast cancer. [PDF]

Heliyon, 2023
Nafea H, Youness RA, Dawoud A, Khater N, Manie T, Abdel-Kader R, Bourquin C, Szabo C, Gad MZ.   +8 more
europepmc   +1 more source

Role of Cystathionine β-Synthase and 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics of Murine Breast Cancer Cells. [PDF]

Antioxidants (Basel), 2023
Santos SS, Rodrigues LOCP, Martins V, Petrosino M, Zuhra K, Ascenção K, Anand A, Abdel-Kader RM, Gad MZ, Bourquin C, Szabo C.   +10 more
europepmc   +1 more source

The mycobacterial guaB1 gene encodes a guanosine 5'-monophosphate reductase with a cystathionine-β-synthase domain. [PDF]

FEBS J, 2022
Knejzlík Z, Doležal M, Herkommerová K, Clarova K, Klíma M, Dedola M, Zborníková E, Rejman D, Pichová I.   +8 more
europepmc   +1 more source