Results 71 to 80 of about 975,983 (211)

Oligomeric status of human cystathionine beta-synthase modulates AdoMet binding

, 2019
Cystathionine beta-synthase (CBS) plays a key role in the metabolism of sulfur-containing amino acids. CBS is a multidomain tetrameric enzymeallosterically activated by S-adenosylmethionine (AdoMet).
Luis Alfonso Martínez-Cruz (2384026), Jan P. Kraus (6422100), Angel L. Pey (355133), Tomas Majtan (6422097)   +3 more
core   +2 more sources

Human polycomb 2 protein is a SUMO E3 ligase and alleviates substrate-induced inhibition of cystathionine beta-synthase sumoylation. [PDF]

PLoS ONE, 2008
Human cystathionine beta-synthase (CBS) catalyzes the first irreversible step in the transsulfuration pathway and commits homocysteine to the synthesis of cysteine. Mutations in CBS are the most common cause of severe hereditary hyperhomocysteinemia.
Nitish Agrawal, Ruma Banerjee
doaj   +1 more source

Semi‐Artificial Photosynthesis Enables Light‐Driven Biomanufacturing in Non‐Photosynthetic Bacteria

Advanced Science, EarlyView.
A non‐invasive strategy exploits endogenous H2S metabolism in B. subtilis to drive in situ CdS biomineralization, enabling tight bio‐abiotic contact without genetic modification. Light harvested by the biomineralized nanoparticles powers NADPH regeneration, elevating 2’‐fucosyllactose and surfactin titres two‐ to three‐fold.
Jie Zheng, Anqi Tong, Wenxin Li, Meng Qiao, Yang Gu, Muhammad Sohail, Shan He, Sheng Yang, Xing Zhang   +8 more
wiley   +1 more source

Blockade of the trans-sulfuration pathway in acute pancreatitis due to nitration of cystathionine β-synthase [PDF]

, 2020
Acute pancreatitis is an inflammatory process of the pancreatic gland that may lead to dysregulation of the trans-sulfuration pathway. The aims of this work were firstly to study the methionine cycle as well as the trans-sulfuration pathway using ...
López Rodas, Gerardo, Taléns Visconti, Raquel, Martí Andrés, Pablo, Rius Pérez, Sergio, Torres Cuevas, Isabel, Franco Vera, Luis, Torres Asensi, Luís, Pérez Garrido, Salvador, Sastre Belloch, Juan, Taléns-Visconti, Raquel, Franco, Luis, Gerardo López-Rodas, Pablo Martí-Andrés, Guerrero, Laura, Isabel Torres-Cuevas, Laura Guerrero, Corrales, Fernando, Juan Sastre, Rius-Pérez, Sergio, Corrales, Fernando J., Sastre, Juan, Salvador Pérez, Pérez, Salvador, Paradela, Alberto, Torres-Cuevas, Isabel, Raquel Taléns-Visconti, Fernando Corrales, Luis Torres, Alberto Paradela, Luis Franco, Torres, Luis, Martí-Andrés, Pablo, López-Rodas, Gerardo, Sergio Rius-Pérez   +33 more
core   +1 more source

Characterization of hyperglycemia due to sub-chronic administration of red ginseng extract via comparative global proteomic analysis

Scientific Reports, 2021
Ginseng (Panax ginseng Meyer) is commonly used as an herbal remedy worldwide. Few studies have explored the possible physiological changes in the liver although patients often self-medicate with ginseng preparations, which may lead to exceeding the ...
Ann-Yae Na, Jung Jae Jo, Oh Kwang Kwon, Piljoung Cho, Yan Gao, Ju-Hyun Kim, Kyu Min Kim, Sung Hwan Ki, Sangkyu Lee   +8 more
doaj   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Cystathionine β-synthase polymorphisms and hyperhomocysteinaemia: an association study [PDF]

European Journal of Human Genetics, 2003
Hyperhomocysteinaemia is generally accepted as an independent and graded risk factor for both arterial occlusive disease and venous thrombosis. The only way of homocysteine degradation is conversion to cysteine in the transsulfuration pathway in which the regulating step is catalysed by cystathionine beta-synthase (CBS). Mild impairment of CBS function
Lievers, K.J.A., Kluijtmans, L.A.J., Heil, S.G., Boers, G.H., Verhoef, P., Den Heijer, M., Trijbels, F.J., Blom, H.J.   +7 more
openaire   +3 more sources

Genotypic Spectrum in a Cohort of Sri Lankan Patients With Homocystinuria

JIMD Reports
Homocystinuria due to cystathionine beta‐synthase (CBS) deficiency is a rare metabolic disorder inherited as an autosomal recessive trait. Spectrum of genetic variants in CBS gene and their correlation with the phenotypes of homocystinuria in Sri Lankan ...
Hewa Warawitage Dilanthi, Kandana Liyanage Subhashinie Jayasena, Nambage Dona Priyani Dhammika, Neluwa Liyanage Ruwan Indika, Matara Mahavidanage Nishani De Silva, Imalke Kankananarachchi, Pushpa Malkanthi Gardiye Punchihewa, Dharma Irugalbandara, Sabine Schroeder, Kosala Karunaratne, Eresha Jasinge   +10 more
doaj   +1 more source

Volatile Sulfur Compounds as a Predictor for Esophagogastroduodenal Mucosal Injury

Gut and Liver, 2008
Background/Aims: Halitosis is a symptom that bothers patients more socially than medically and its pathogenic mechanisms are unclear and treatment armamenterium is limited. Clinicians generally ignored active interventions.
doaj   +1 more source

Cystathionine β-synthase affects organization of cytoskeleton and modulates carcinogenesis in colorectal carcinoma cells

Frontiers in Oncology, 2023
BackgroundCystathionine β-synthase (CBS), one of three enzymes that endogenously produce hydrogen sulfide, is extensively studied for its relevance in the cells of various tumors.
Veronika Liskova, Barbora Chovancova, Petr Babula, Ingeborg Rezuchova, Kristina Ploth Pavlov, Miroslava Matuskova, Olga Krizanova, Olga Krizanova   +7 more
doaj   +1 more source