Results 151 to 160 of about 555,922 (178)

P35 Exacerbation of the septic response in cystathionine-gamma-lyase deficient mice

Nitric Oxide, 2014
Previous studies reported both beneficial and detrimental roles of hydrogen sulfide (H2S) in various models of critical illness. The goal of our study was to compare the outcome of septic shock in wild-type mice and in mice deficient in cystathionine-gamma-lyase (CSE).
Ciro Coletta, Csaba Szabo
openaire   +1 more source

Cystathionine gamma-lyase deficiency exaggerates diethylnitrosamine-induced liver damage in mice

Nitric Oxide - Biology and Chemistry
Cystathionine gamma-lyase (CSE) is a key enzyme in reverse transsulfuration pathway and contributes to the majority of H2S generation in liver tissues via cysteine metabolism. Dysfunction of the CSE/H2S system is linked to both chronic and acute liver damage.
Guangdong Yang
exaly   +3 more sources

Glucocorticoids suppress cystathionine gamma-lyase expression and H2S production in lipopolysaccharide-treated macrophages

Cellular and Molecular Life Sciences, 2010
Hydrogen sulfide (H(2)S) plays an important role in inflammation. We showed that macrophages expressed the H(2)S-forming enzyme cystathionine gamma-lyase (CSE) and produced H(2)S. Lipopolysaccharide (LPS) stimulated the CSE expression and H(2)S production rate. l-cysteine reduced LPS-induced nitric oxide (NO) production.
Xiao-Yan, Zhu, Shu-Juan, Liu, Yu-Jian, Liu, Shan, Wang, Xin, Ni   +4 more
openaire   +2 more sources

Cystathionine gamma lyase expression/activity delays endothelial senescence

Free Radical Biology and Medicine, 2022
Sofia Bibli, Jiong Hu, Matthias Leisegang, Ilka Wittig, Ralf Brandes, Andreas Papapetropoulos, Fragiska Sigala, Ingrid Fleming   +7 more
openaire   +1 more source

Human cystathionine gamma-lyase: developmental and in vitro expression of two isoforms.

The Biochemical journal, 2000
Cystathionine gamma-lyase (CGL) is the last enzyme of the trans-sulphuration pathway, which converts methionine into cysteine. To study the possible differences in enzymic activity of the two human cystathionine gamma-lyase isoforms characterized earlier, these were separately expressed in human kidney embryonic 293T cells.
A L, Levonen, R, Lapatto, M, Saksela, K O, Raivio   +3 more
openaire   +1 more source

Cystathionine gamma-lyase

1990
Dietmar Schomburg, Margit Salzmann
openaire   +1 more source

Changes in cystathionine gamma-lyase levels in rat liver during lactation.

Biochemistry and molecular biology international, 1994
Rat liver cystathionine gamma-lyase activity increased rapidly with the onset of lactation, reaching a maximum value at week 2 and slowly decreasing thereafter. In non-lactating rats, from which the litters had been removed on the day of birth, the activity of this enzyme increased only minimally.
S, Awata, K, Nakayama, A, Sato, M, Kawamura, I, Suzuki, H, Kodama   +5 more
openaire   +1 more source

Cystathionine gamma-lyase/H2 S signaling facilitates myogenesis under aging and injury condition.

FASEB Journal, 2021
Lingyun Wu, Yanjie Zhang, Simon J Lees
exaly  

[Expressions of cystathionine-beta-synthase and cystathionine-gamma-lyase in the corpus cavernosum smooth muscle of castrated rats].

Zhonghua nan ke xue = National journal of andrology, 2014
To study the expressions of cystathionine-beta-synthase (CBS) and cystathionine-gamma-lyase (CSE) in the corpus cavernosum smooth muscle of castrated rats and their roles in erectile dysfunction after castration.We randomly assigned 40 eight-week-old male SD rats to groups A (2-week sham-operation), B (4-week sham-operation), C (2-week castration) and ...
Hua, Luo, Lun-Bo, Liu, Ai-Ping, Feng, Yang, Gao, Gao-Yuan, Liao, Ming-Quan, Qiu   +5 more
openaire   +1 more source

Sulfhydration of perilipin 1 is involved in the inhibitory effects of cystathionine gamma lyase/hydrogen sulfide on adipocyte lipolysis

Biochemical and Biophysical Research Communications, 2020
HuaMin Wang, Bin Geng
exaly