Results 161 to 170 of about 7,388 (204)

Cystathionine gamma‐lyase aggravates periodontal damage in traumatic occlusion mouse models

Journal of Periodontal Research, 2020
AbstractBackground and objectiveThough impacts of traumatic occlusion (TO) on periodontal tissues and roles of cystathionine γ‐lyase (Cth) gene in the regulation of bone homeostasis have been studied by many, no consensus has been reached so far on whether TO deteriorates the periodontium and precise roles of Cth in occlusal trauma.
Liyuan Chen, Caizhu Lu, Yongmei Hua
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Age-Dependent Allergic Asthma Development and Cystathionine Gamma-Lyase Deficiency

Antioxidants & Redox Signaling, 2017
The pathogenic mechanisms for the higher prevalence of allergic asthma in children than in adults have not been settled. The aim of the present study is to examine whether the age-dependent development of allergic asthma is caused by age-dependent expression of cystathionine gamma-lyase (CSE), a key enzyme that catalyzes the production of hydrogen ...
Peipei, Wang, Lingyun, Wu, Yongjun, Ju, Ming, Fu, Tian, Shuang, Zhongming, Qian, Rui, Wang   +6 more
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Cystathionine γ-lyase from Streptomyces phaeochromoǵenes

1987
Publisher Summary This chapter discusses the determination of cystathionine γ- Lyase from streptomyces phaeochromogenes. Cystathionine γ-lyase was first purified and crystallized from rat liver, but is also widely distributed among fungi. The microbial enzyme is purified and crystallized from Streptomyces phaeochromogenes (IFO 3105).
T, Nagasawa, H, Kanzaki, H, Yamada
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Cystathionine γ‐lyase of Saccharomyces cerevisiae: Structural gene and cystathionine γ‐synthase activity

Yeast, 1993
AbstractPurification of Saccharomyces cerevisiae cystathionine γ‐lyase (γ‐CTLase) was hampered by the presence of a protein migrating very close to it in various types of column chromatography. The enzyme and the contaminant were nevertheless separated by polyacrylamide gel electrophoresis.
B, Ono, N, Ishii, K, Naito, S, Miyoshi, S, Shinoda, S, Yamamoto, S, Ohmori   +6 more
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Is cystathionine gamma-lyase protein expressed in the heart?

Biochemical and Biophysical Research Communications, 2012
Hydrogen sulfide (H(2)S) has emerged as an important gasotransmitter, offering protection against ischemia-reperfusion damage to the heart. Cystathionine gamma-lyase (CSE) is believed to be the major H(2)S-generating enzyme in the heart. Quite contrary to the general contemplation, CSE protein in cardiac tissues has not been convincingly detected and ...
Ming, Fu, Weihua, Zhang, Guangdong, Yang, Rui, Wang   +3 more
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Regulation of cystathionine γ‐lyase in Saccharomyces cerevisiae

Yeast, 1991
AbstractRegulation of the two enzymes in reverse trans‐sulfuration was investigated in Saccharomyces cerevisiae. In wild‐type strains, cystathionine γ‐lyase, but not cystathionine β‐synthase, was derepressed nearly 15‐fold if cells were starved for both inorganic and organic sulfur compounds. In a met17 strain which is defective of O‐acetylserine and O‐
B, Ono, K, Naito, Y, Shirahige, M, Yamamoto   +3 more
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Abstract 21141: Cystathionine Gamma-Lyase Regulates Autophagy in Ischemic Endothelial Cells

Circulation, 2017
Introduction: Peripheral arterial disease (PAD) is a chronic arterial occlusive disease leading to lower limb ischemia. Autophagy is a cell adaptive response associated with ischemic stress that may act as a double edged sword. It is essential during tissue ischemia, but may also phagocytize more organelles promoting cell death.
Saranya Rajendran, Christopher G Kevil
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Cystathionine gamma-lyase deficiency exaggerates diethylnitrosamine-induced liver damage in mice

Nitric Oxide
Cystathionine gamma-lyase (CSE) is a key enzyme in reverse transsulfuration pathway and contributes to the majority of H2S generation in liver tissues via cysteine metabolism. Dysfunction of the CSE/H2S system is linked to both chronic and acute liver damage.
Samantha Ligi, Arm Ali, Guangdong Yang
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Suicide inactivation of bacterial cystathionine .gamma.-synthase and methionine .gamma.-lyase during processing of L-propargylglycine

Biochemistry, 1979
L-Propargylglycine, a naturally occurring gamma, delta-acetylenic alpha-amino acid, induces mechanism-based inactivation of two pyridoxal phosphate dependent enzymes of methionine metabolism: (1) cystathionine gamma-synthease, which catalyzes a gamma-replacement reaction in methionine biosynthesis, and (2) methionine gamma-lyase, which catalyzes a ...
M, Johnston, D, Jankowski, P, Marcotte, H, Tanaka, N, Esaki, K, Soda, C, Walsh   +6 more
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The therapeutic potential of cystathionine gamma-lyase in temporomandibular inflammation-induced orofacial hypernociception

Physiology & Behavior, 2018
Hydrogen sulfide (H2S) is an endogenous neuromodulator produced mainly by the enzyme cystathionine gamma-lyase (CSE) in peripheral tissues. A pronociceptive role of endogenously produced H2S has been previously reported by our group in a model of orofacial inflammatory pain.
Bruna M, Santos, Emanuela G, Garattini, Luiz G S, Branco, Christie R A, Leite-Panissi, Glauce C, Nascimento   +4 more
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