Results 61 to 70 of about 7,941 (171)

Immobilization of Saccharomyces cerevisiae Cystathionine γ-Lyase and Application of the Product to Cystathionine Synthesis [PDF]

Applied and Environmental Microbiology, 2004
ABSTRACT Cystathionine γ-lyase of Saccharomyces cerevisiae was immobilized to aminohexyl-Sepharose through the cofactor pyridoxal 5′-phosphate and was characterized with respect to its cystathionine γ-synthase activity.
Shuzo, Yamagata, Tsuyoshi, Akamatsu, Tomonori, Iwama   +2 more
openaire   +2 more sources

Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap

Biology Open, 2015
In addition to its role in the endogenous synthesis of cysteine, cystathionine gamma-lyase (CGL) is a major physiological source of the vasorelaxant hydrogen sulfide.
Hua Jiang, K. Joseph Hurt, Kelsey Breen, Sally P. Stabler, Robert H. Allen, David J. Orlicky, Kenneth N. Maclean   +6 more
doaj   +1 more source

The influence of calcitriol on indicators of apoptosis, inflammation and oxidative stress in the myocardium of rats under conditions of modulation of the hydrogen sulfide / cystathionine-gamma-lyase system

Reports of Vinnytsia National Medical University, 2023
Annotation. Vitamin D plays an important role in the control of the cardiovascular system, including myocardial remodeling and hypertrophy. Hydrogen sulfide (H2S) is an important mediator of cardiomyocyte adaptive mechanisms to stress factors.
R. S. Ostrenyuk, N. Zaichko
semanticscholar   +1 more source

Functional importance of Ser323 in cysteine desulfhydrase and cystathionine gamma-lyase MccB of Staphylococcus aureus.

Journal of Microbiology
Pyridoxal 5'-phosphate (PLP)-dependent enzymes participate in various reactions involved in methionine and cysteine metabolism. The representative foodborne pathogen Staphylococcus aureus expresses the PLP-dependent enzyme MccB, which exhibits both ...
Dukwon Lee, Hyojeong Lee, Kyumi Byun, Eun-Su Park, Nam-Chul Ha   +4 more
semanticscholar   +1 more source

Cystathionine .GAMMA.-lyase activity in the cephamycin C producer Streptomyces lactamdurans.

The Journal of Antibiotics, 1981
Extracts of the cephamycin C producer S. lactamdurans were found to possess cystathionine gamma-lyase activity (E.C. 4.4.1.1). This represents the first demonstration of this enzyme of the reverse transsulfuration pathway in a prokaryotic organism. A likely involvement of reverse transsulfuration in antibiotic synthesis is indicated by the fact that ...
B A, Kern, E, Inamine
openaire   +3 more sources

Volatile Sulfur Compounds as a Predictor for Esophagogastroduodenal Mucosal Injury

Gut and Liver, 2008
Background/Aims: Halitosis is a symptom that bothers patients more socially than medically and its pathogenic mechanisms are unclear and treatment armamenterium is limited. Clinicians generally ignored active interventions.
doaj   +1 more source

Two-photon ratiometric imaging of endogenous reactive inorganic sulfur species in the cellular cushion toward formaldehyde

Biosensors and Bioelectronics: X, 2023
To address the potential biological relationship between reactive inorganic sulfur species (RISSs) and formaldehyde, the novel two-photon ratiometric RISSs probes (PH-RISSs) were synthesized practically with high selectivity and sensitivity toward RISSs ...
Linye Wu, Bo Wang, Gangqin Xi, Yajuan Fu, Shuting Yu, Qi Chen, Jianxin Chen, Liqin Zheng, Shuangmu Zhuo, Daliang Li   +9 more
doaj   +1 more source

Investigation of the association of cystathionine gamma-lyase (CTH) and vitamin D-binding protein (GC) genes polymorphisms with preeclampsia in some pregnant women attending prenatal care at a general hospital in Lagos Nigeria

The Scientific World Journal
Preeclampsia is associated with high maternal and foetal morbidity and mortality. Studies have demonstrated that polymorphisms in the genes that regulate vascular dynamics may play vital roles in the development of chronic hypertension and preeclampsia ...
J. Igbalaye, A. Wusu, Abiola F. Oyedapo, Azeezat O. Ajape, A. Shakunle, A. Fatai, Solomon O. Rotimi   +6 more
semanticscholar   +1 more source

Hyperhomocysteinemia and Vitamin B Deficiency as Potential Aggravating Factors in Huntington's Disease: A Prospective Monocentric Study

Movement Disorders, EarlyView.
Abstract Background Although not confirmed, some studies have suggested that elevated homocysteine levels are common in patients with Huntington's disease (HD). Its clinical relevance remains unclear. Objectives We aimed to assess vitamin B and homocysteine levels in HD patients and explore the relationships among hyperhomocysteinemia, vitamin B ...
Salomé Puisieux, Elise Pourié, Céline Bonnet, Lucie Hopes, Solène Frismand, Myriam Bronner, Virginie Roth, Marion Wandzel, Natacha Sloboda, Laetitia Lambert, Abderrahim Oussalah, Amélia Julien, Irina Rotaru, Rosa‐Maria Guéant‐Rodriguez, Jean Louis Guéant, Carine Bossenmeyer‐Pourié, Mathilde Renaud   +16 more
wiley   +1 more source

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

Phytotherapy Research, EarlyView.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi, Renda Chahna, Francesca Maffei, Alma Martelli, Vincenzo Calderone, Carmela Fimognari, Eleonora Turrini   +6 more
wiley   +1 more source