Results 131 to 140 of about 64,052 (260)
Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.This systematic review compiles and analyses 364 studies on chronic kidney disease (CKD) that investigated extracellular vesicles (EVs) for diagnostic and therapeutic applications. By systematically categorizing data according to EV source and cargo, it provides an integrated overview of EV application for CKD, highlighting common approaches and shared
Tunahan Ergunay +2 more
wiley +1 more source
, 2015 Background: chronic kidney disease (CKD) diagnosis relies on glomerular filtration rate (eGFR) estimation, traditionally using the creatinine-based Modification of Diet in Renal Disease (MDRD) equation.
Aitken, Grant +7 more
core +1 more source
Teriparatide in Two Patients With Mucopolysaccharidosis Type IVB
JIMD Reports, Volume 67, Issue 3, May 2026.ABSTRACT Mucopolysaccharidosis Type IV is a multisystem lysosomal storage disease characterized by severe skeletal dysplasia resulting from impaired degradation of the glycosaminoglycans keratan sulfate and chondroitin‐6‐sulfate. The condition is classified into Types A and B based on the underlying enzyme deficiency.
Mark Wijnen +5 more
wiley +1 more source
Protein Science, Volume 35, Issue 5, May 2026.Abstract Legumain is a lysosomal cysteine protease that plays a central role in antigen processing for MHC class II presentation. Beyond its canonical proteolytic activity, legumain can also function as a peptide ligase or transpeptidase. This non‐canonical activity becomes particularly relevant under pathophysiological conditions such as cancer and ...
Rupert Klaushofer +3 more
wiley +1 more source
Protein Science, Volume 35, Issue 5, May 2026.Abstract Marine cone snails produce a diverse array of bioactive peptides, known as conotoxins, in their venom. Given their high target potency and specificity, conotoxins are attractive compounds for the development of precision research tools and pharmacological agents.
Celeste M. Hackney +12 more
wiley +1 more source
Evaluating Protein Enrichment Methods to Improve Biomarker Discovery in Equine Cerebrospinal Fluid
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.Here, we compared two protein enrichment methods—ProteoMiner Small‐Capacity and PreOmics Enrich‐iST—for proteomic analysis of equine cerebrospinal fluid (CSF). PreOmics Enrich‐iST achieved superior depletion of high‐abundance proteins and identified a greater number of low‐abundance, neuropathology‐relevant proteins than ProteoMiner or native digestion.
Foti Federico +5 more
wiley +1 more source
Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract
American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik +3 more
wiley +1 more source
Clinical Physiology and Functional Imaging, Volume 46, Issue 3, May 2026.Abstract This study evaluates mannitol as a clearance marker for measuring glomerular filtration rate (GFR) in outpatients with chronic kidney disease (CKD). Multi‐sample iohexol clearance served as the reference method. Twenty patients with CKD, stages 3–4, received bolus injections of both clearance markers simultaneously.
Katalin Kiss +3 more
wiley +1 more source
Rapid improvement of renal microcirculatory homeostasis by liraglutide following diabetes induction
Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4066-4081, May 2026.Abstract Aims Renal microvascular dysfunction is a central driver of diabetic kidney disease, yet the potential for rapid therapeutic reversal remains obscure. We investigated the effect of short‐term liraglutide on early changes in the renal microcirculation post‐induction of diabetes.
Yuan Li +8 more
wiley +1 more source