Results 141 to 150 of about 43,347 (262)

Cystatin C (CST3), the candidate gene for hereditary cystatin C amyloid angiopathy (HCCAA), and other members of the cystatin gene family are clustered on chromosome 20p11.2

open access: yes, 1993
The cystatin C gene (CST3) encodes a low-molecular-weight cysteine proteinase inhibitor belonging to family II of the cystatin super family and is mutated in cases of hereditary cystatin C amyloid angiopathy (HCCAA).
Schnittger, Susanne   +5 more
core   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

open access: yesThe FEBS Journal, Volume 293, Issue 13, Page 3758-3787, July 2026.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka   +3 more
wiley   +1 more source

Cystatin C functions in vitro and in vivo. Studies on target enzyme inhibition by cystatin C variants and cystatin C deficient mice.

open access: yes, 1998
Cystatin C variants with Arg8, Leu9 and/or Val10 replaced by Gly residues were produced by site-directed mutagenesis and E. coli expression. Their interactions with the target proteases, cathepsin B, L, H and S, were studied in vitro in order to provide ...
Håkansson, Katarina
core  

Proteolytic remodelling of the extracellular matrix by pericytes

open access: yesThe FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard   +4 more
wiley   +1 more source

The Use of Ambulatory Blood Pressure Monitoring in Pediatric Heart Transplant Recipients

open access: yesPediatric Transplantation, Volume 30, Issue 7, July 2026.
ABPM identified important hypertension phenotypes in pediatric heart transplant recipients. White coat hypertension was common among those with elevated clinic blood pressures and often progressed to ABPM‐confirmed hypertension. Hypertensive patients had higher left ventricular mass, supporting ABPM use for the diagnosis and treatment of hypertension ...
Bushra Anjum   +7 more
wiley   +1 more source

Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin

open access: yes, 1987
When an excess of human cystatin C or chicken cystatin was mixed with papain, an enzyme-inhibitor complex was formed immediately. The residual free cystatin was then progressively converted to a form with different electrophoretic mobility and ...
Machleidt, Werner   +5 more
core  

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