Results 51 to 60 of about 61,196 (252)

Serum Cystatin C as a Biomarker in Diffuse Large B-Cell Lymphoma

Scientia Pharmaceutica, 2017
Elevated serum levels of cystatin C are found to be related to poor outcome and metastatic potential of some malignant disorders. To evaluate the clinical prominence of serum cystatin C in diffuse large B-cell lymphoma (DLBCL), blood samples were ...
Nada E. Hammouda, Manal A. Salah El-Din, Mamdouh M. El-Shishtawy, Amal M. El-Gayar   +3 more
doaj   +1 more source

Impact of cystatin C-derived glomerular filtration rate in patients undergoing transcatheter aortic valve implantation

Frontiers in Cardiovascular Medicine, 2023
BackgroundChronic kidney disease (CKD) impacts prognosis in patients undergoing transcatheter aortic valve implantation (TAVI). While estimated glomerular filtration rate (eGFR) calculated from serum creatinine [eGFR (creatinine)] is affected by body ...
Yusuke Kure, Tsukasa Okai, Yasuhiro Izumiya, Hisako Yoshida, Kazuki Mizutani, Tomohiro Yamaguchi, Mana Ogawa, Atsushi Shibata, Asahiro Ito, Yosuke Takahashi, Toshihiko Shibata, Daiju Fukuda   +11 more
doaj   +1 more source

Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study [PDF]

, 2018
Aims: To test the prognostic value of emerging biomarkers in the Reduction of Events by Darbepoetin Alfa in Heart Failure (RED-HF) trial. Methods and results: Circulating cardiac [N-terminal pro-B-type natriuretic peptide (NT-proBNP), and high ...
Alehagen, Arimoto, Balling, Bolignano, Cabassi, Dupont, Gaggin, Gravning, Grodin, Guisado Espartero, Haehling, Harrell, Jackson, Lassus, Lassus, Lok, Maisel, Maisel, McMurray, McMurray, Miller, Miller, Nagarajan, Park, Pascual-Figal, Pencina, Pencina, Pocock, Ponikowski, Rahimi, Rush, Shlipak, Swedberg, Tentzeris, Zamora   +34 more
core   +4 more sources

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis [PDF]

, 2015
International audienceAbstractThe activity of cysteine cathepsin B increased markedly in lung homogenates and in bronchoalveolar lavage fluids (BALF) of the mouse model of bleomycin-induced lung fibrosis after 14 days of challenge.
Couillin, Isabelle, Gombault, Aurélie, Kasabova, Mariana, Lalmanach, Gilles, Lecaille, Fabien, Marchand-Adam, Sylvain, Reinheckel, Thomas, Villeret, Bérengère   +7 more
core   +3 more sources

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

Annals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa, Aurosman Pappus Sahu, David B. Rye, Lynn Marie Trotti, Irina A. Elcheva, Vladimir S. Spiegelman, James R. Connor   +6 more
wiley   +1 more source

Exploration of chronic kidney disease prevalence estimates using new measures of kidney function in the health survey for England

, 2015
Background: chronic kidney disease (CKD) diagnosis relies on glomerular filtration rate (eGFR) estimation, traditionally using the creatinine-based Modification of Diet in Renal Disease (MDRD) equation.
Aitken, Grant, Day, Julie, Fraser, Simon D.S., Mindell, Jennifer S., Moon, Graham, O’Donoghue, Donal, Roderick, Paul J., Taal, Maarten W.   +7 more
core   +1 more source

Serum Cystatin C for the diagnosis of acute Kidney Injury in Patients Admitted in the Emergency Department [PDF]

, 2015
BACKGROUND: Early diagnosis of acute kidney injury (AKI) at emergency department (ED) is a challenging issue. Current diagnostic criteria for AKI poorly recognize early renal dysfunction and may cause delayed diagnosis.
Bongiovanni, Cristina, Buggi, Marco, Cardelli, Patrizia, Di Somma, Salvatore, Gori, Chiara Serena, Hur, Mina, Magrini, Laura, Salerno, Gerardo   +7 more
core   +4 more sources

Hiperurisemia dan Cystatin C

Jurnal Analis Medika Biosains (JAMBS), 2020
Hiperurisemia merupakan keadaan kadar asam meningkat dalam darah. Kadarnya yang meningkat dapat menyebabkan penyakit, salah satunya yaitu adalah gangguan ginjal. Parameter cystatin C dipakai sebagai parameter yang lebih unggul dibanding kreatinin dalam menilai fungsi ginjal.
Meri Meri, Yane Liswanti
openaire   +2 more sources