Results 31 to 40 of about 61,196 (252)

Cystatin C deficiency in human atherosclerosis and aortic aneurysms [PDF]

, 2014
The pathogenesis of atherosclerosis and abdominal aortic aneurysm involves breakdown of the elastic laminae. Elastolytic cysteine proteases, including cathepsins S and K, are overexpressed at sites of arterial elastin damage, but whether endogenous local
Chapman, Harold A., Ducharme, Anique, Grubb, Anders, Lee, Richard Theodore, Libby, Peter, Rhode, Luis H., Ridker, Paul M., Shi, Guo-Ping, Sukhova, Galina K.   +8 more
core   +1 more source

Cystatin C: A Primer for Pharmacists [PDF]

Pharmacy, 2020
Pharmacists are at the forefront of dosing and monitoring medications eliminated by or toxic to the kidney. To evaluate the effectiveness and safety of these medications, accurate measurement of kidney function is paramount. The mainstay of kidney assessment for drug dosing and monitoring is serum creatinine (SCr)-based estimation equations.
Hilary R. Teaford, Jason N. Barreto, Kathryn J. Vollmer, Andrew D. Rule, Erin F. Barreto   +4 more
openaire   +3 more sources

Cystatin-C is an independent prognostic factor for survival in multiple myeloma and is reduced by bortezomib administration

Haematologica, 2009
Background Renal impairment is a common complication of multiple myeloma. Cystatin-C is considered an accurate marker of glomerular filtration rate in several renal disorders.
Evangelos Terpos, Eirini Katodritou, Evangelos Tsiftsakis, Efstathios Kastritis, Dimitrios Christoulas, Anastasia Pouli, Eurydiki Michalis, Evgenia Verrou, Konstantinos Anargyrou, Konstantinos Tsionos, Meletios A. Dimopoulos, Konstantinos Zervas   +11 more
doaj   +1 more source

Serum cystatin C is an independent biomarker associated with the renal resistive index in patients with chronic kidney disease. [PDF]

PLoS ONE, 2018
Cystatin C is a cysteine protease inhibitor that is produced by nearly all human cells. The serum level of cystatin C is a stronger predictor of the renal outcome and the risk of cardiovascular events than the creatinine level.
Ayu Ogawa-Akiyama, Hitoshi Sugiyama, Masashi Kitagawa, Keiko Tanaka, Akifumi Onishi, Toshio Yamanari, Hiroshi Morinaga, Haruhito Adam Uchida, Kazufumi Nakamura, Hiroshi Ito, Jun Wada   +10 more
doaj   +1 more source

Cystatin C Is Not Causally Related to Coronary Artery Disease. [PDF]

PLoS ONE, 2015
Strong and independent associations between plasma concentration of cystatin C and risk of cardiovascular disease (CVD) suggests causal involvement of cystatin C.The aim of our study was to assess whether there is a causal relationship between plasma ...
Patrik Svensson-Färbom, Peter Almgren, Bo Hedblad, Gunnar Engström, Margaretha Persson, Anders Christensson, Olle Melander   +6 more
doaj   +1 more source

Cystatin C is Associated With Plaque Phenotype and Plaque Burden

Kidney & Blood Pressure Research, 2016
Background/Aims: The relationship between carotid artery plaque burden, phenotype and serum cystatin C at normal and impaired renal function is still unclear. Methods: Demographic characteristics, carotid ultrasonography and other relevant information of
Yufeng Wen, Dan Xia, Yanchun Wang, Huiping Zhang, Haibo Li, Gholam Ali, Yongqing Gao, Jian Li, Wenjie Sun, Linlin Li   +9 more
doaj   +1 more source

Maternal Cystatin C Serum is Higher in Women with Severe Preeclampsia

Indonesian Journal of Obstetrics and Gynecology, 2014
Objective: To determine the comparison between maternal cystatin C serum in severe preeclampsia and normal pregnancy. Method: This was an observational study with cross sectional analytic approach. The subjects are sixty women with severe preeclampsia
Kurnia M. Isasari, Wim T Pangemanan, Iskandar Zulqarnain, Kemas Rahadiyanto   +3 more
doaj   +1 more source

Cystatin C: a candidate biomarker for amyotrophic lateral sclerosis. [PDF]

PLoS ONE, 2010
Amyotrophic lateral sclerosis (ALS) is a fatal neurologic disease characterized by progressive motor neuron degeneration. Clinical disease management is hindered by both a lengthy diagnostic process and the absence of effective treatments.
Meghan E Wilson, Imene Boumaza, David Lacomis, Robert Bowser   +3 more
doaj   +1 more source

Cystatin C and lactoferrin concentrations in biological fluids as possible prognostic factors in eye tumor development [PDF]

, 2013
Objectives. To investigate the possible role of cystatin C in eye biological fluids locally and in serum and lactoferrin revealing anti-tumor activity in eye tumor development. Background.
Ananthi S, Bobek LA, Butler MW, de Souza GA, Decock J, Ha NH, Keppler D, Korolenko TA, Kos J, Kos J, Magister S, Mann DM, Mirkovic B, Mulaomerovic A, Terpos E, Tomita M, Turk V, Wasselius J, Wassélius J, Wei M   +19 more
core   +1 more source

Estimation of glomerular filtration rate from serum creatinine and cystatin C in octogenarians and nonagenarians [PDF]

, 2013
Background: Equations to estimate GFR have not been well validated in the elderly and may misclassify persons with chronic kidney disease (CKD). We measured GFR and compared the performance of the Modification of Diet in Renal Disease (MDRD), the Chronic
Araujo, Lara Q., Cendoroglo, Maysa Seabra, Kirsztajn, Gianna Mastroianni, Lopes, Marcelo B., Nishida, Sonia Kiyomi, Passos, Michelle T., Sesso, Ricardo de Castro Cintra   +6 more
core   +3 more sources