Results 21 to 30 of about 34,990 (232)

Cystatin C: A Primer for Pharmacists [PDF]

Pharmacy, 2020
Pharmacists are at the forefront of dosing and monitoring medications eliminated by or toxic to the kidney. To evaluate the effectiveness and safety of these medications, accurate measurement of kidney function is paramount. The mainstay of kidney assessment for drug dosing and monitoring is serum creatinine (SCr)-based estimation equations.
Hilary R. Teaford, Jason N. Barreto, Kathryn J. Vollmer, Andrew D. Rule, Erin F. Barreto   +4 more
openaire   +3 more sources

Cystatin C and Uncontrolled Hypertension

The Anatolian Journal of Cardiology, 2020
Increased serum level of cystatin C, a sensitive biomarker for renal function, seems to predict adverse cardiovascular events. We investigated the predictive value of serum cystatin C for controlling hypertension in an observational study.We screened 1037 adults residing in both rural and urban communities.
Omaygenç, Mehmet Onur, Özcan, Özgür Ulaş, Çakal, Beytullah, Karaca, Oğuz   +3 more
openaire   +5 more sources

Cystatin C in Alzheimer's disease [PDF]

Frontiers in Molecular Neuroscience, 2012
Changes in expression and secretion levels of cystatin C (CysC) in the brain in various neurological disorders and in animal models of neurodegeneration underscore a role for CysC in these conditions. A polymorphism in the CysC gene (CST3) is linked to increased risk for Alzheimer's disease (AD).
Kaur, Gurjinder, Levy, Efrat
openaire   +3 more sources

Association of serum cystatin C level with coronary atherosclerotic plaque burden: a comprehensive analysis of observational studies and genetic study

BMC Cardiovascular Disorders, 2023
Background and Aims Epidemiological studies show that high circulating cystatin C is associated with risk of cardiovascular disease (CVD), independent of creatinine-based renal function measurements.
Jun Chen, Jiayi Shen, Yuesong Pan, Jing Jing, Yongjun Wang, Tiemin Wei, Lingchun Lyu   +6 more
doaj   +1 more source

Effects of Cystatin C on Cognitive Impairment in Older Chinese Adults

American Journal of Alzheimer's Disease and Other Dementias, 2020
Objective: To find a suitable dividing value to classify cystatin C and evaluate the association between cognition and levels of cystatin C. Methods: Using data from the China Health and Retirement Longitudinal Study, We conducted a longitudinal analysis
Zhizhen Cui MS, Guizhen Cao MS, Youyi Wang BS, Qinghua Ma MS, Congju Wang MS, Yong Xu MS, Hongpeng Sun PhD, Yana Ma PhD   +7 more
doaj   +1 more source

Development and Analytical Validation of a Smartphone‐Based Quantitative Lateral Flow Immunoassay for Serum Cystatin‐C [PDF]

J Clin Lab Anal
We developed a gold nanoparticle‐based lateral flow immunoassay that pairs a fixed‐geometry smartphone reader with an Android application for quantitative serum Cystatin‐C measurement. The 15‐min assay covered 0.32–8.00 mg/L with a 0.15 mg/L detection limit and CVs below 10%.
Lian Y, Zheng R, Yang C, Luo Y, Zhang N, Lian G, Li B.   +6 more
europepmc   +2 more sources

Diagnostic and prognostic performance of urinary neutrophil gelatinase‐associated lipocalin in patients with cirrhosis and acute kidney injury

Hepatology, EarlyView., 2022
Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino, Salvatore Piano, Matteo Stenico, Marta Tonon, Alessandra Brocca, Valeria Calvino, Simone Incicco, Nicola Zeni, Roberta Gagliardi, Chiara Cosma, Martina Zaninotto, Patrizia Burra, Umberto Cillo, Daniela Basso, Paolo Angeli   +14 more
wiley   +1 more source

Serum Cystatin C as a Potential Marker for Glomerular Filtration Rate in Patients with Cholangiocarcinoma

International Journal of Hematology-Oncology and Stem Cell Research, 2020
Background: Cholangiocarcinoma (CCA) is the second most common primary hepatobiliary cancer. These patients have meager prognosis and short-term survival. Precise assessment of glomerular filtration rate is a fundamental aspect of clinical care in cancer
Mang Ngaih Ciin, Tanakorn Proungvitaya, Temduang Limpaiboon, Ubon Cha’on, Sittiruk Roytrakul, Siriporn Proungvitaya   +5 more
doaj   +1 more source

Mendelian randomization study supports the causal association between serum cystatin C and risk of diabetic nephropathy

Frontiers in Endocrinology, 2022
AimsCystatin C, an inhibitor of cysteine protease, has been used as a biomarker for estimating glomerular filtration rate. However, the causal relation between cystatin C and diabetic nephropathy remains uncertain.MethodsWe assessed the causal effect of ...
Baiyu Feng, Yu Lu, Lin Ye, Lijun Yin, Yingjun Zhou, Anqun Chen   +5 more
doaj   +1 more source

Increased Cystatin C in Astrocytes of Transgenic Mice Expressing the K670N-M671L Mutation of the Amyloid Precursor Protein and Deposition in Brain Amyloid Plaques

Neurobiology of Disease, 2001
Cystatin C is an essential secretory cofactor for neurogenesis with potent protease inhibitor activities. Polymorphisms of cystatin C are genetically associated with Alzheimer's disease (AD), and the L68Q mutation causes hereditary cerebral hemorrhage ...
Tiana Steinhoff, Eva Moritz, M.Axel Wollmer, M.Hasan Mohajeri, Stefan Kins, Roger M. Nitsch   +5 more
doaj   +1 more source