Results 21 to 30 of about 33,345 (227)

Effects of Cystatin C on Cognitive Impairment in Older Chinese Adults

open access: yesAmerican Journal of Alzheimer's Disease and Other Dementias, 2020
Objective: To find a suitable dividing value to classify cystatin C and evaluate the association between cognition and levels of cystatin C. Methods: Using data from the China Health and Retirement Longitudinal Study, We conducted a longitudinal analysis
Zhizhen Cui MS   +7 more
doaj   +1 more source

Serum Cystatin C as a Potential Marker for Glomerular Filtration Rate in Patients with Cholangiocarcinoma

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2020
Background: Cholangiocarcinoma (CCA) is the second most common primary hepatobiliary cancer. These patients have meager prognosis and short-term survival. Precise assessment of glomerular filtration rate is a fundamental aspect of clinical care in cancer
Mang Ngaih Ciin   +5 more
doaj   +1 more source

Mendelian randomization study supports the causal association between serum cystatin C and risk of diabetic nephropathy

open access: yesFrontiers in Endocrinology, 2022
AimsCystatin C, an inhibitor of cysteine protease, has been used as a biomarker for estimating glomerular filtration rate. However, the causal relation between cystatin C and diabetic nephropathy remains uncertain.MethodsWe assessed the causal effect of ...
Baiyu Feng   +5 more
doaj   +1 more source

Diagnostic and prognostic performance of urinary neutrophil gelatinase‐associated lipocalin in patients with cirrhosis and acute kidney injury

open access: yesHepatology, EarlyView., 2022
Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino   +14 more
wiley   +1 more source

Increased Cystatin C in Astrocytes of Transgenic Mice Expressing the K670N-M671L Mutation of the Amyloid Precursor Protein and Deposition in Brain Amyloid Plaques

open access: yesNeurobiology of Disease, 2001
Cystatin C is an essential secretory cofactor for neurogenesis with potent protease inhibitor activities. Polymorphisms of cystatin C are genetically associated with Alzheimer's disease (AD), and the L68Q mutation causes hereditary cerebral hemorrhage ...
Tiana Steinhoff   +5 more
doaj   +1 more source

Changes in Serum Cystatin C Levels and the Associations With Cognitive Function in Alzheimer's Disease Patients

open access: yesFrontiers in Aging Neuroscience, 2022
Background and ObjectiveCystatin C is indicated to be involved in the pathogenesis of Alzheimer's disease (AD) and cognitive impairment. Our objective is to examine the serum Cystatin C levels, and to clarify the correlations between serum Cystatin C and
Xueping Chen   +9 more
doaj   +1 more source

Cystatin C and Aging Success [PDF]

open access: yesArchives of Internal Medicine, 2008
To our knowledge, the effect of kidney function on successful aging has not been examined.We evaluated the relationship between cystatin C and aging success during a 6-year follow-up in the Cardiovascular Health Study, a community-based cohort of older adults (aged >or= 65 years). Successful aging was defined as remaining free of cardiovascular disease,
Mark J, Sarnak   +9 more
openaire   +2 more sources

Longitudinal study of Cystatin C in healthy term newborns

open access: yesClinics, 2011
OBJECTIVE: The purpose of this study was to determine the levels of Cystatin C in healthy term newborns in the first month of life. INTRODUCTION: Cystatin C may be a suitable marker for determining the glomerular filtration rate because it is not ...
Ana Carolina de Albuquerque Cavalcanti Ferreira Novo   +3 more
doaj   +1 more source

Cystatin C uptake in the eye [PDF]

open access: yesGraefe's Archive for Clinical and Experimental Ophthalmology, 2004
As a secreted protein, cystatin C is assumed to play its role in the extracellular compartment, where it can inhibit virtually all cysteine proteases of families C1 (cathepsin B, L, S) and C13 (mammalian legumain-related proteases). Since many of its potential target enzymes in the eye reside in intracellular compartments, we sought evidence for a ...
Wassélius, Johan   +4 more
openaire   +2 more sources

Kadar Cystatin-C Serum Sebagai Penanda Fungsi Ginjal Bayi Prematur

open access: yesSari Pediatri, 2016
Latar belakang. Cystatin-C dipertimbangkan menjadi pemeriksaan potensial pengganti kreatinin serum sebagai penanda fungsi ginjal. Kadar cystatin-C serum lebih mendekati nilai laju filtrasi glomerulus dibandingkan dengan kreatinin serum.
Dinna Meinardaniawati   +2 more
doaj   +1 more source

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