Results 11 to 20 of about 33,345 (227)

Glomerular Filtration Rate Estimation Based on Cystatin C Formulas among Neonates [PDF]

open access: yesIranian Journal of Neonatology, 2021
Background: Glomerular filtration rate (GFR) is the best indicator to assess renal function; however, it is difficult to perform it, especially in neonates.
Nasrin Khalesi   +7 more
doaj   +1 more source

Serum Cystatin C Levels Are Associated With Obesity in Adolescents Aged 14–17 Years

open access: yesFrontiers in Endocrinology, 2022
BackgroundThe association between serum cystatin C levels and obesity has not been fully explored in adolescents. This study aimed to explore the association between serum cystatin C levels and obesity in adolescents of different sexes.MethodsWe ...
Ying-Xiang Huo   +7 more
doaj   +1 more source

Cystatin C is downregulated in prostate cancer and modulates invasion of prostate cancer cells via MAPK/Erk and androgen receptor pathways. [PDF]

open access: yesPLoS ONE, 2009
Cystatin C is believed to prevent tumor progression by inhibiting the activities of a family of lysosomal cysteine proteases. However, little is known about the precise mechanism of cystatin C function in prostate cancer.
Barbara Wegiel   +7 more
doaj   +1 more source

Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats. [PDF]

open access: yesPLoS ONE, 2017
Cystatin C, a marker of kidney injury, is freely filtered in the glomeruli and reabsorbed by the proximal tubules. Megalin and cubilin are endocytic receptors essential for reabsorption of most filtered proteins.
Danny Jensen   +8 more
doaj   +1 more source

Cystatin C and Cardiovascular Risk [PDF]

open access: yesClinical Chemistry, 2009
Abstract Background: Patients with chronic kidney disease (CKD) are at high risk for developing cardiovascular disease (CVD) and cardiovascular events. Cystatin C, a protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect ...
TAGLIERI, NEVIO, Koenig W, Kaski C.
openaire   +6 more sources

Cystatin C: A Primer for Pharmacists [PDF]

open access: yesPharmacy, 2020
Pharmacists are at the forefront of dosing and monitoring medications eliminated by or toxic to the kidney. To evaluate the effectiveness and safety of these medications, accurate measurement of kidney function is paramount. The mainstay of kidney assessment for drug dosing and monitoring is serum creatinine (SCr)-based estimation equations.
Hilary R. Teaford   +4 more
openaire   +3 more sources

Cystatin C in Alzheimer's disease [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2012
Changes in expression and secretion levels of cystatin C (CysC) in the brain in various neurological disorders and in animal models of neurodegeneration underscore a role for CysC in these conditions. A polymorphism in the CysC gene (CST3) is linked to increased risk for Alzheimer's disease (AD).
Kaur, Gurjinder, Levy, Efrat
openaire   +3 more sources

GFR Estimation After Cystatin C Reference Material Change

open access: yesKidney International Reports, 2021
Introduction: Glomerular filtration rate (GFR) is routinely estimated with cystatin C. In June 2010, the International Federation of Clinical Chemistry (IFCC) released a certified cystatin C reference material (ERM-DA471/IFCC), and new cystatin C ...
Stefanie W. Benoit   +7 more
doaj   +1 more source

Cystatin C and Uncontrolled Hypertension

open access: yesThe Anatolian Journal of Cardiology, 2020
Increased serum level of cystatin C, a sensitive biomarker for renal function, seems to predict adverse cardiovascular events. We investigated the predictive value of serum cystatin C for controlling hypertension in an observational study.We screened 1037 adults residing in both rural and urban communities.
Omaygenç, Mehmet Onur   +3 more
openaire   +5 more sources

Association of serum cystatin C level with coronary atherosclerotic plaque burden: a comprehensive analysis of observational studies and genetic study

open access: yesBMC Cardiovascular Disorders, 2023
Background and Aims Epidemiological studies show that high circulating cystatin C is associated with risk of cardiovascular disease (CVD), independent of creatinine-based renal function measurements.
Jun Chen   +6 more
doaj   +1 more source

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