Cystatin C as a Renal Biomarker in Infants with Congenital Anomalies of the Kidney and Urinary Tract (CAKUT): A Systematic Review [PDF]
DiagnosticsBackground: The evaluation of renal function in neonates is challenging due to maternal creatinine transfer, reduced muscle mass, and non-steady-state physiology.
Mihaela Dobre +4 more
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NMR STUDIES OF HUMAN CYSTATIN C – STABLE ISOTOPE LABELING OF HUMAN CYSTATIN C
TASK Quarterly, 2014 The objective of this study was to obtain a double and triple labeled human cystatin C (hCC). Another objective was to record sets of 2D and 3D NMR spectra of the hCC dimer (in a solution) using a 700MHz spectrometer.
PRZEMYSŁAW JURCZAK +1 more
doaj +2 more sources
Long-term cystatin C trajectories and cognitive decline in diabetes and non-diabetes: evidence from a national Chinese cohort [PDF]
Frontiers in MedicineBackgroundThe relationship between Cystatin C levels and cognitive function remains unclear. This study aims to investigate the association between cumulative changes and trajectory patterns of Cystatin C and cognitive decline in diabetes and non ...
Xiangyang Zhou +5 more
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Glomerular Filtration Rate Estimation Based on Cystatin C Formulas among Neonates [PDF]
Iranian Journal of Neonatology, 2021 Background: Glomerular filtration rate (GFR) is the best indicator to assess renal function; however, it is difficult to perform it, especially in neonates.
Nasrin Khalesi +7 more
doaj +1 more source
Cystatin C is downregulated in prostate cancer and modulates invasion of prostate cancer cells via MAPK/Erk and androgen receptor pathways. [PDF]
PLoS ONE, 2009 Cystatin C is believed to prevent tumor progression by inhibiting the activities of a family of lysosomal cysteine proteases. However, little is known about the precise mechanism of cystatin C function in prostate cancer.
Barbara Wegiel +7 more
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Serum Cystatin C Levels Are Associated With Obesity in Adolescents Aged 14–17 Years
Frontiers in Endocrinology, 2022 BackgroundThe association between serum cystatin C levels and obesity has not been fully explored in adolescents. This study aimed to explore the association between serum cystatin C levels and obesity in adolescents of different sexes.MethodsWe ...
Ying-Xiang Huo +7 more
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Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats. [PDF]
PLoS ONE, 2017 Cystatin C, a marker of kidney injury, is freely filtered in the glomeruli and reabsorbed by the proximal tubules. Megalin and cubilin are endocytic receptors essential for reabsorption of most filtered proteins.
Danny Jensen +8 more
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Cystatin C and Cardiovascular Risk [PDF]
Clinical Chemistry, 2009 Abstract Background: Patients with chronic kidney disease (CKD) are at high risk for developing cardiovascular disease (CVD) and cardiovascular events. Cystatin C, a protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect ...
TAGLIERI, NEVIO, Koenig W, Kaski C.
openaire +6 more sources
Cystatin C: A Primer for Pharmacists [PDF]
Pharmacy, 2020 Pharmacists are at the forefront of dosing and monitoring medications eliminated by or toxic to the kidney. To evaluate the effectiveness and safety of these medications, accurate measurement of kidney function is paramount. The mainstay of kidney assessment for drug dosing and monitoring is serum creatinine (SCr)-based estimation equations.
Hilary R. Teaford +4 more
openaire +3 more sources
GFR Estimation After Cystatin C Reference Material Change
Kidney International Reports, 2021 Introduction: Glomerular filtration rate (GFR) is routinely estimated with cystatin C. In June 2010, the International Federation of Clinical Chemistry (IFCC) released a certified cystatin C reference material (ERM-DA471/IFCC), and new cystatin C ...
Stefanie W. Benoit +7 more
doaj +1 more source