Results 91 to 100 of about 25,149 (297)

Lysosomal oxidation of LDL alters lysosomal pH, induces senescence and increases secretion of pro-inflammatory cytokines in human macrophages [PDF]

, 2019
Objective We have shown that aggregated low density lipoproteins (LDL) is internalised by macrophages and oxidised in lysosomes by redox-active iron.
Ahmad, Feroz, Leake, David S.
core   +1 more source

Laser‐Induced Graphene for Early Disease Detection: A Review

ChemElectroChem, Volume 12, Issue 6, March 15, 2025.
Laser‐induced graphene (LIG) has emerged as a superior alternative to conventionally synthesized graphene due to its flexibility, cost‐effectiveness, scalability, high conductivity, and the ability to customize its properties for various applications. This review highlights LIG′s transformative potential in electrochemical biosensing, focusing on early
Sri Ramulu Torati, Gymama Slaughter
wiley   +1 more source

Cognitive functions and behavioural profiles in children with cystinosis treated with cysteamine and correlation with treatment duration

Middle East Current Psychiatry, 2022
Background Cystinosis is a rare autosomal recessive disease. Children with nephropathic cystinosis (NCTN) have evidence of intellectual dysfunction and behavioural abnormalities which are attributed to renal dysfunction, metabolic disarrangement, and ...
Fatma M. Atia, Weam Ryad Alfaleet, Somaya H. Shaheen, Neveen A. Soliman   +3 more
doaj   +1 more source

UV-light-driven prebiotic synthesis of iron–sulfur clusters [PDF]

, 2017
Iron–sulfur clusters are ancient cofactors that play a fundamental role in metabolism and may have impacted the prebiotic chemistry that led to life.
Bonfio, Claudia, Evans, David J., Jin, Lin, Mansy, Sheref, Mansy, Sheref S., Sasselov, Dimitar, Sasselov, Dimitar D., Scintilla, Simone, Shah, Sachin, Sutherland, John, Sutherland, John D., Szostak, Jack, Szostak, Jack W., Valer, Luca   +13 more
core   +1 more source

Cutting‐Edge Aptasensing Approaches for Electrochemical Detection of Exosomes Utilizing MXenes

ChemElectroChem, EarlyView.
This work notably summarizes research on 2D MXenes/MXene's‐hybrid‐based nanoplatforms patterned with aptamers as an alternative to antibodies affording highly sensitive and robust biosensing of exosomes as well as their efficient isolation. The exosomes are highlighted as a valuable source of biomarkers and with the immobilization approaches of ...
Andrej Vikartovský, Natália Košútová, Lenka Lorencová, Peter Kasák, Tomáš Bertók, Ján Tkáč   +5 more
wiley   +1 more source

Improved method for the preparation of malonyl coenzyme A

Journal of Lipid Research, 1968
Malonyl coenzyme A is synthesized by transacylating S-malonyl-N-decanoyl cysteamine with coenzyme A. A simplified procedure for the preparation of S-malonyl-N-decanoyl cysteamine, using cysteamine as starting material, is described.
Hans Mohrhauer, Kirsten Christiansen, Minerva Gan, Manfred Deubig, Ralph T. Holman   +4 more
doaj  

Sensing of Alzheimer’s Disease and Multiple Sclerosis Using Nano-Bio Interfaces [PDF]

, 2017
It is well understood that patients with different diseases may have a variety of specific proteins (e.g., type, amount, and configuration) in their plasmas.
Aghaie, Afsaneh, Aghamollaii, Vajiheh, Aghaverdib, Haniyeh, Alekhamis, Zahra, Atyabi, Fatemeh, Azhdarzadeh, Morteza, Bargahi, Afshar, Derakhshankhah, Hossein, Ghasemid, Forough, Hajipoura, Mohammad Javad, Hashemi, Ehsan, Linne, Uwe, Lotfabadi, Alireza, Mahmoudi, Morteza, Maserat Mashhadi, Marzie, Nabipour, Iraj, Raoufib, Mohammad, Sheibani, Sara, Tafakhori, Abbas, Vali, Hojatollah   +19 more
core   +2 more sources

Studying the Ingress of Ag Nanoparticles into Imprinted Nanocavities by Nanoimpact Electrochemistry

ChemElectroChem, EarlyView.
The ingress of single silver nanoparticles (NPs) into nanocavities is studied by nanoimpact electrochemistry. The NP‐imprinted matrix approach is used to create well‐defined nanocavities that reuptake selectively silver NPs based on their size as detected by the current–time oxidation transients of single NPs.
Hila Sagi-Cohen, Pavel Savchenko, Daniel Mandler   +2 more
wiley   +1 more source

Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication

Neurobiology of Disease, 2020
A number of publications have reported that cysteamine has significant therapeutic effects on several aspects of Parkinson's disease (PD)-related pathology but none of these studies have evaluated its impact on pathological forms of α-Synuclein (α-Syn ...
Alberto Siddu, Linda Suzanne David, Nadine Lauinger, Xiuqing Chen, Martine Saint-Pierre, Melanie Alpaugh, Thomas Durcan, Francesca Cicchetti   +7 more
doaj  

_In vivo_ photoacoustic molecular imaging with simultaneous multiple selective targeting using antibody-conjugated gold nanorods [PDF]

, 2008
The use of gold nanorods for photoacoustic molecular imaging in vivo with simultaneous multiple selective targeting is reported. The extravasation of multiple molecular probes is demonstrated, and used to probe molecular information of cancer cells. This
Ann-Ann Ding, Carolina Poe, Chao-Kang Liao, Chen-Wei Wei, Churng-Ren Wang, Dar-Bin Shieh, Pai-Chi Li, Suwen Jhan, Ya-Na Wu   +8 more
core   +1 more source