Results 81 to 90 of about 12,238 (214)

Synthesis and Characterization of a Cationic Thiomer Based on Ethyl Cellulose for Realization of Mucoadhesive Tablets and Nanoparticles

International Journal of Nanomedicine, 2022
Deni Rahmat, Clairine Devina Faculty of Pharmacy, Pancasila University, Srengseng Sawah, Jagakarsa, South Jakarta, 12640, IndonesiaCorrespondence: Deni Rahmat, Faculty of Pharmacy, Pancasila University, Srengseng Sawah, Jagakarsa, South Jakarta, 12640 ...
Rahmat D, Devina C
doaj  

Cystamine and Cysteamine As Inhibitors of Transglutaminases In Vivo [PDF]

, 2018
Cystamine is commonly used as a transglutaminase inhibitor. This disulfide undergoes reduction in vivo to the aminothiol compound, cysteamine. Thus, the mechanism by which cystamine inhibits transglutaminase activity in vivo could be due to either ...
Jeitner, Thomas M, Cooper, Arthur J. L., Pinto, John T.   +2 more
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Brunner's glands of the rat during cysteamine ulceration

, 1981
Duodenal ulcers can be produced in rats by subcutaneous administration of cysteamine-HCl. The pathogenesis of these ulcers has not been fully explained. Increased acid secretion is necessary but not sufficient for ulcer production.
Poulsen, Steen Seier
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Influence of supplemented coated-cysteamine on morphology, apoptosis and oxidative stress status of gastrointestinal tract

BMC Veterinary Research, 2019
Background Cysteamine was coated to cover its odor and maintain the stability. However, coated cysteamine (CC) has not been clearly evaluated for its effects on the gastrointestinal mucosa status. We hypothesize that the appropriate CC supplementation in
Hongnan Liu, Miaomiao Bai, Bie Tan, Kang Xu, Rong Yu, Ruilin Huang, Yulong Yin   +6 more
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A New and Rapid LC-MS/MS Method for the Determination of Cysteamine Plasma Levels in Cystinosis Patients

Pharmaceuticals
Cystinosis is a rare lysosomal storage disorder caused by autosomal recessive mutations in the CTNS gene that encodes for the cystine transporter cystinosin, which is expressed on the lysosomal membrane mediating the efflux of cystine.
Raffaele Simeoli, Sara Cairoli, Marcella Greco, Francesco Bellomo, Alessandro Mancini, Chiara Rossi, Carlo Dionisi Vici, Francesco Emma, Bianca Maria Goffredo   +8 more
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Cysteamine-colon and cysteamine-duodenum lesions in rats. Attenuation by gastric pentadecapeptide BPC 157, cimetidine, ranitidine, atropine, omeprazole, sulphasalazine and methylprednisolone

, 2001
Recently, we showed cysteamine-duodenal lesions without gastric acid, since they were induced also in gastrectomized rats, as in naive rats, and they were inhibited by the novel stomach pentadecapeptide BPC 157 as well as standard antiulcer drugs (i.e ...
Sven Seiwerth, Darko Mikus, Tihomil Ziger, Darko Perovic, Dinko Stancic Rokotov, Zoran Simec, Ingrid Prkacin, Branko Turkovic, Stjepan Mise, Ivan Balen, Tomislav Anic, Jadranka Separovic, Josip Aralica, Martina Lovric Bencic, Predrag Sikiric, Bozidar Sebecic, Marijan Petek, Gorana Aralica, Ivo Sjekavica, Ljiljana Komericki, Zeljko Grabarevic, Mario Staresinic, Rudolf Rucman, Alenka Boban Blagaic, Zoran Ivasovic, SKROZA, Nevena, Miroslav Gjurasin, Ivo Rotkvic   +27 more
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Copper deficiency in patients with cystinosis with cysteamine toxicity

, 2013
Item does not contain fulltextOBJECTIVES: To assess whether copper deficiency plays a role in the recently described cysteamine toxicity in patients with cystinosis, and to examine whether polymorphisms in copper transporters, lysyl oxidase, and/or type ...
Lillen, Marc R, Heuvel, L.P.W.J. van den, Malfait, Fransiska, Lilien, M.R., Besouw, Martine T, De Paepe, Anne, Lilien, Marc R., Emma, Francesco, van den Heuvel, Lambertus P., Symoens, Sofie, Janssen, Mirian C., Janssen, M.C.H., Nobili, F., Emma, F., Skovby, Flemming, Besouw, Martine T P, Greco, Marcella, Desmet, K., Symoens, S., Janssen, Mirian C, Schneider, Jerry, Schneider, J., Besouw, M.T., Lilien, Marc R, Greco, M., Malfait, F., Cornelissen, Elisabeth A, Levtchenko, Elena N, Paepe, A. de, Skovby, F., van den Heuvel, Lambertus P, Levtchenko, E.N., Nobili, François, Cornelissen, Elisabeth A., Desmet, Koen, Besouw, Martine T. P., Cornelissen, E.A.M., Levtchenko, Elena N.   +37 more
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The mechanism of gastrin release in cysteamine-induced duodenal ulcer

, 1982
Duodenal ulcer can be induced in rats by a single dose of cysteamine. The ulcer formation is accompanied by acid hypersecretion and elevated serum gastrin levels.
Poulsen, Steen Seier
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Adherence to Cysteamine Therapy Among Patients Diagnosed with Cystinosis in Saudi Arabia: A Prospective Cohort Study

Pharmacy
Cystinosis is a rare autosomal recessive disorder in which cystine crystals accumulate within the cellular lysosomes, causing damage to multiple organs.
Reem Algasem, Nedaa Zainy, Essam Alsabban, Hamad Almojalli, Khalid Alhasan, Tariq Ali, Deiter Broering, Hassan Aleid   +7 more
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Antioxidant effect of cysteamine in brain cortex of young rats

, 2008
Cysteamine is a cystine-depleting drug used in the treatment of cystinosis, a metabolic disorder caused by deficiency of the lysosomal cystine carrier.
Biasibetti, Micheli, Kessler, Adriana, Wannmacher, Clovis Milton Duval, Wyse, Angela Terezinha de Souza, Wajner, Moacir, Melo, Denizar Alberto da Silva, Dutra Filho, Carlos Severo   +6 more
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