Results 201 to 210 of about 10,851 (230)

Cysteamine

Drug Discovery Today, 2013
Cysteamine is an amino thiol with the chemical formula HSCH2CH2NH2. Endogenously, cysteamine is derived from coenzyme A degradation, although its plasma concentrations are low. Most experience with cysteamine as a drug originates from the field of the orphan disease cystinosis, in which cysteamine is prescribed to decrease intralysosomal cystine ...
Besouw, Martine, Masereeuw, R., van den Heuvel, Lambert, Levtchenko, Elena   +3 more
openaire   +2 more sources

Cysteamine Toxicity in Patients with Cystinosis

The Journal of Pediatrics, 2011
To report new adverse effects of cysteamine.Detailed clinical information was obtained from the patients' physicians.New adverse events were reported in 8 of 550 patients with cystinosis treated with cysteamine in Europe during the last 5 years. Detailed clinical information was not available for 2 of these patients, 1 of whom died from cerebral ...
Besouw, M.T., Bowker, R., Dutertre, J.P., Emma, F., Gahl, W.A., Greco, M., Lilien, M.R., McKiernan, J., Nobili, F., Schneider, J.A., Skovby, F., van den Heuvel, L.P., van den Heuvel, L.P., van 't Hoff, W.G., Levtchenko, E.N.   +14 more
openaire   +5 more sources

Cysteamine-induced adrenocortical necrosis in rats

Experimental and Molecular Pathology, 1981
Abstract The development of adrenocortical hemorrhagic necrosis following treatment with cysteamine was studied in rats. Increased vascular permeability, originating in the inner cortical layers, resulted in congestion, platelet aggregation, edema, and hemorrhage which, over a 12-hr period, spread outward to the capsule.
D J, McComb, K, Kovacs, H C, Horner, G T, Gallagher, U, Schwedes, K H, Usadel, S, Szabo   +6 more
openaire   +2 more sources

Unveiling thiol biomarkers: Glutathione and cysteamine

Clinica Chimica Acta
The physiological and clinical importance of Glutathione and Cysteamine is emphasized by their participation in a range of conditions, such as diabetes, cancer, renal failure, Parkinson's disease, and hypothyroidism. This necessitates the requirement for accessible, expedited, and cost-efficient testing that can facilitate clinical diagnosis and ...
M G, Gopika, Surya, Gopidas, Gokul S, Jayan, P S, Arathy, Beena, Saraswathyamma   +4 more
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METABOLISM OF CYSTEAMINE

The Journal of Pharmacology and Experimental Therapeutics, 1957
R A, SALVADOR, C, DAVISON, P K, SMITH
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Neurobiological actions of cysteamine.

Federation proceedings, 1985
Somatostatin (SS)-related peptides act within discrete brain regions to inhibit adrenal epinephrine (E) secretion, to prevent hypothermia, and to produce hyperthermia. Depletion of brain concentrations of these SS-related peptides using cysteamine (CSH) or central administration of an SS receptor antagonist increases adrenal E secretion and impairs ...
M, Brown, L, Fisher, R T, Mason, J, Rivier, W, Vale   +4 more
openaire   +1 more source

Cysteamine dioxygenase

1987
R B, Richerson, D M, Ziegler
openaire   +2 more sources

CYSTEAMINE FOR CYSTINOSIS

The Lancet, 1978
openaire   +2 more sources

Hepatotoxicity of cysteamine?

The Journal of Pediatrics, 1983
W A, Gahl, J D, Schulman, J G, Thoene, J, Schneider   +3 more
openaire   +2 more sources

FORMULATING CYSTEAMINE INJECTION

The Lancet, 1977
openaire   +2 more sources