Results 31 to 40 of about 11,095 (222)

A monoclinic polymorph of cysteamine hydrochloride [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
cloruro de 2-mercaptoetano-aminio), C(2)H(8)NS(+)·Cl(-), la sal de hidrocloruro de cisteamina, en contraste con el polimorfo triclínico previamente informado [Kim et al. (2002▶). Polyhedron, 21, 225-228], cristalizado en el sistema cristalino monoclínico.
Saeed Ahmad, Muhammad Ashraf Shaheen, H. Stoeckli‐Evans   +2 more
openaire   +4 more sources

Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication

Neurobiology of Disease, 2020
A number of publications have reported that cysteamine has significant therapeutic effects on several aspects of Parkinson's disease (PD)-related pathology but none of these studies have evaluated its impact on pathological forms of α-Synuclein (α-Syn ...
Alberto Siddu, Linda Suzanne David, Nadine Lauinger, Xiuqing Chen, Martine Saint-Pierre, Melanie Alpaugh, Thomas Durcan, Francesca Cicchetti   +7 more
doaj   +1 more source

Cysteamine-mediated clearance of antibiotic-resistant pathogens in human cystic fibrosis macrophages. [PDF]

PLoS ONE, 2017
Members of the Burkholderia cepacia complex are virulent, multi-drug resistant pathogens that survive and replicate intracellularly in patients with cystic fibrosis (CF). We have discovered that B. cenocepacia cannot be cleared from CF macrophages due to
Chandra L Shrestha, Kaivon D Assani, Hannah Rinehardt, Florentina Albastroiu, Shuzhong Zhang, Richard Shell, Amal O Amer, Larry S Schlesinger, Benjamin T Kopp   +8 more
doaj   +1 more source

The specificity of cysteamine oxygenase

FEBS Letters, 1975
Oxidation of cysteamine to hypotaurine is catalyzed by cysteamine oxygenase (EC 1.13.11.19), a non-heme iron enzyme of large distribution [l-3] . A similar oxidation of cysteine to cysteine sulfinic acid has been reported to require a different oxygenase [4,.5]. Specificity of cysteamine oxygenase has been studied earlier in this laboratory by assaying
Cavallini, D., Federici, G., Ricci, G., Duprè, S., Antonucci, A., De Marco, C.   +5 more
openaire   +2 more sources

Metabolic interactions between cysteamine and epigallocatechin gallate [PDF]

, 2017
Phase II clinical trials indicate that the combination of cysteamine plus epigallocatechin gallate (EGCG) is effective against cystic fibrosis in patients bearing the most frequent etiological mutation (CFTRΔF508).
RAIA, VALERIA, José Manuel Bravo-San Pedro (3621344), Valentina Izzo (192358), ESPOSITO, SPERANZA, MAIURI, MARIA CHIARA, Valentina Sica (3621341), Sylvère Durand (2864786), Durand, Sylvère, Federico Pietrocola (2864783), Speranza Esposito (663714), Pietrocola, Federico, Kroemer, Guido, David Enot (252040), Lachkar, Sylvie, Luigi Maiuri (663723), IZZO, VALENTINA, Chery, Alexis, Alexis Chery (2864780), Guido Kroemer (82802), Maria Chiara Maiuri (327528), Maiuri, Luigi, Bravo San Pedro, José Manuel, Sica, Valentina, Sylvie Lachkar (232826), Enot, David, Valeria Raia (524374)   +25 more
core   +1 more source

Beyond the Fixed Charge: A New On‐Tissue Derivatisation Strategy Employing Photoionisable Chromophores for Mass Spectrometry Imaging of Amino‐Containing Metabolites

Angewandte Chemie, EarlyView.
We introduce a novel chemical derivatisation strategy for the UV‐activated detection of elusive metabolites. Incorporation of a tocopherol‐active chromophore allows for the detection of tagged analytes as photoionised radical cations, selectively induced by a 266 nm laser.
Sofia R. McGowan, Andrew J. Tague, Ashna A. Kumar, Marie Ranson, Christopher J. T. Hyland, Shane R. Ellis   +5 more
wiley   +2 more sources

Cysteamine in Maturation Medium Enhances Nuclear Maturation and Fertilization Rate of Sheep Oocytes In Vitro

Hayati Journal of Biosciences, 2020
Low nuclear maturation and fertilization rate is one obstacle in the in vitro embryo production which decrease embryo yield. This problem is presumable related with high production of reactive oxygen species (ROS) during maturation process.
Feni Dwi Kartika Gulo, Ni Wayan Kurniani Karja, Mohamad Agus Setiadi   +2 more
doaj   +1 more source

Synthesis of Six Natural Products Enabled by Selective Hydroxylation of Orcinaldehyde‐Like Substrates With an Enzyme Library

Angewandte Chemie, EarlyView.
Achieving selective (sp3)C–H hydroxylation can streamline the synthesis of complex organic molecules. Biocatalysis presents an opportunity to realize this transformation, however, identifying useful enzymes that enable synthetic strategies can be a challenge due to limitations in enzyme substrate scope.
Gonzalo J. Villegas Rodríguez, Evan O. Romero, Jonathan C. Perkins, Diego N. Rojas, Maximilian S. Hrigora, Alison R. H. Narayan   +5 more
wiley   +2 more sources

A Voltammetric Sensor Based on NiO Nanoparticle-Modified Carbon-Paste Electrode for Determination of Cysteamine in the Presence of High Concentration of Tryptophan

Journal of Chemistry, 2013
A carbon-paste electrode modified with ferrocenecarboxaldehyde and NiO nanoparticle (NiO/NPs) was used for the sensitive and selective voltammetric determination of cysteamine in the presence of tryptophan.
Hassan Karimi-Maleh, Maryam Salimi-Amiri, Fatemeh Karimi, Mohammad A. Khalilzadeh, Mehdi Baghayeri   +4 more
doaj   +1 more source

Increased human dermal microvascular endothelial cell survival induced by cysteamine [PDF]

, 2013
Contains fulltext : 125972.pdf (Publisher’s version ) (Open Access)BACKGROUND: Cystinosis is an autosomal recessive disease caused by intralysosomal cystine accumulation, treated with cysteamine.
I. Bongaers, Bongaers, I., R. van Eijsden, M. Dewerchin, Besouw, M., Kluijtmans, L.A., van Eijsden, R., Kluijtmans, L., L. Kluijtmans, van den Heuvel, L., Levtchenko, E., Dewerchin, M., Eijsden, R. van, E. Levtchenko, M. Besouw, L. den van Heuvel, Heuvel, L.P. van den, Levtchenko, E.N.   +17 more
core   +1 more source