Results 51 to 60 of about 10,629 (179)

Cysteamine selectively enhances neuropeptide Y2 receptor binding activity

open access: yes, 1992
Affinity labeling of [125I]NPY to the bovine hippocampal NPY receptor has revealed a 50 kDa specific binding protein, the Y2 receptor. Cysteamine (10 μM – 10 mM) specifically enhanced NPY specific labeling of the Y2 receptor without affecting ...
Li, Wei, Hexum, Terry D
core   +1 more source

Brunner's glands of the rat during cysteamine ulceration

open access: yes, 1981
Duodenal ulcers can be produced in rats by subcutaneous administration of cysteamine-HCl. The pathogenesis of these ulcers has not been fully explained. Increased acid secretion is necessary but not sufficient for ulcer production.
Poulsen, Steen Seier
core  

The protective effects of cysteamine, putrescine, and the combination of cysteamine and putrescine on fibrosarcoma induced in mice with 3-methylcholanthrene

open access: yes, 2016
In this study, the protective effects of cysteamine, putrescine, and the combination of cysteamine and putrescine were investigated in mice with fibrosarcoma induced with 3-methylcholanthrene (3-MC).
Erdağ D.   +11 more
core   +1 more source

Effect of cysteamine on serum enzymes and creatinine levels.

open access: yes, 2012
Tumor bearing mice were treated with increasing doses of cysteamine and serum was collected from tail veins twice, i.e., pre-cysteamine treatment (day 4) and post- treatment (day 18).
Benjamin Rubin (169516)   +6 more
core   +1 more source

Cysteamine hydrochloride eye drop solution for the treatment of corneal cystine crystal deposits in patients with cystinosis: an evidence-based review

open access: yes, 2018
Achini K Makuloluwa, Fatemeh Shams Tennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, UK Abstract: Cystinosis is a rare, autosomal recessive disorder leading to defective transport of cystine out of lysosomes.
Makuloluwa AK, Shams F
core  

Cysteamine 에 의한 세포사멸, ER 스트레스, 그리고 염증반응의 조절 기전

open access: yes, 2021
학위논문 (박사) -- 서울대학교 대학원 : 의과대학 의과학과, 2021. 2. 김인규.시스티아민은 Coenzyme A 분해과정에서 생성되는 thiolamine으로 세포내에서 PKC1, Transglutaminase 2 (TG2), caspase 3의 효소활성을 억제한다.
이진행
core  

Antioxidant effect of cysteamine in brain cortex of young rats

open access: yes, 2008
Cysteamine is a cystine-depleting drug used in the treatment of cystinosis, a metabolic disorder caused by deficiency of the lysosomal cystine carrier.
Biasibetti, Micheli   +6 more
core  

Prolonged release pharmaceutical composition comprising cysteamine or salt thereof

open access: yes, 2021
A prolonged release multiple unit dosage form, preferably pellets, of cysteamine, cystamine or a pharmaceutically acceptable salt thereof, preferably cysteamine bitartrate, with a non gastro-resistant coating is described. The dosage form is particularly
A. Maroni   +3 more
core  

The mechanism of gastrin release in cysteamine-induced duodenal ulcer

open access: yes, 1982
Duodenal ulcer can be induced in rats by a single dose of cysteamine. The ulcer formation is accompanied by acid hypersecretion and elevated serum gastrin levels.
Poulsen, Steen Seier
core  

Clinical Efficacy of Cysteamine Application for Melasma: A Meta-Analysis

open access: yes
Background: Melasma is a challenging, acquired hyperpigmentary disorder. The gold standard treatment is Kligman’s formulation, which contains hydroquinone, tretinoin, and dexamethasone, but its long-term use is limited by the risk of exogenous ...
Tzong-Yuan Juang   +5 more
core   +1 more source

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