Results 81 to 90 of about 20,516 (271)

Successful treatment of solar lentigines by topical application of stabilized cysteamine: A vehicle‐controlled, double‐blind randomized study

Health Science Reports
Background Solar lentigines are common hyperpigmented lesions typically appearing after 50 years of age and associated with negative psychological effects in affected individuals. Topical depigmenting products, such as hydroquinone and even the Kligman's
Nasrin Saki, Vahideh Modabber, Hengameh Kasraei, Behrooz Kasraee   +3 more
doaj   +1 more source

Nanostructured luminescently labeled nucleic acids [PDF]

, 2017
Important and emerging trends at the interface of luminescence, nucleic acids and nanotechnology are: (i) the conventional luminescence labeling of nucleic acid nanostructures (e.g. DNA tetrahedron); (ii) the labeling of bulk nucleic acids (e.g. single‐
Adleman, Ai, Beater, Bi, Branton, Cao, Casini, Chen, Corstjens, Deng, Ding, Ding, Ding, Divsar, Du, Duan, Dunn, ENCODE, Fortina, Fortina, Gerling, Gommers-Ampt, Goodman, Han, He, He, He, He, He, Hembury, Heuer-Jungemann, Horikoshi, Hu, Huang, Jia, Ke, Kim, Knoblauch, Kricka, Kricka, Kwok, Lee, Li, Li, Lin, Liu, Liu, Liu, Lu, Ma, Maden, Mouse ENCODE Consortium, Nangreave, Nirenberg, Obliosca, Orbach, Ozhalici-Unal, Park, Park, Parker, Petty, Pinehiro, Randeria, Ren, Richards, Rijke, Ritchie, Rotaru, Rothemund, Seeman, Seferos, Severcan, Sharma, Shchepinov, Shen, Simonetti, Stahl, Stolper, Taton, Vanyushin, Vasudevan, Vummidi, Wang, Wang, Wang, Wang, Wang, Wang, Wu, Wu, Yan, Yang, Yang, Yang, Ye, Yeh, Yu, Yuan, Yurke, Zhang, Zhang, Zhang, Zhang, Zhao, Zheng, Zhou   +105 more
core   +1 more source

Tri‐Modal Anticancer Strategies with Doxorubicin‐Loaded Iron Oxide Nanoparticles Integrating Chemo and Magneto‐Photothermal Therapeutic Effects

Advanced NanoBiomed Research, EarlyView.
Maghemite nanoparticles functionalized with doxorubicin enable synergistic chemo‐magneto‐photothermal therapy. Combining pH‐sensitive drug release with localized heating at clinically relevant low doses enhances tumor cell death while minimizing toxicity.
Rosalía López‐Méndez, Nuria Lafuente‐Gómez, Eva Céspedes, Mónica Dhanjani, Marina París‐Ogáyar, Francisco José Terán, Aida Serrano, Julio Camarero, Gorka Salas, Claire Wilhelm, Álvaro Somoza, Ana Espinosa   +11 more
wiley   +1 more source

Effect of melatonin and/or cysteamine on development and vitrification of buffalo embryos

Asian Pacific Journal of Reproduction, 2017
Objective: To assess the effects of melatonin and/or cysteamineon in vitro maturation, culturing and post-warming of buffalo embryos.Methods: Buffalo oocytes were classified into control, cysteamine (50 μM), melatonin (10 ng/mL) and cysteamine (50 μM ...
Mohamed MM El-Sokary, Mohamed El-Raey, Karima GhM Mahmoud, Mahmoud EA Abou El-Roos, Gamal MS Sosa   +4 more
doaj   +1 more source

A novel sustained‐release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers

Pharmacology Research & Perspectives, 2021
The strict intake regimen of cysteamine bitartrate formulations, associated with side effects, is a concern for the treatment compliance in cystinosis therapy.
Cécile L. Berends, Lisa Pagan, Michiel J. vanEsdonk, Naomi B. Klarenbeek, Kirsten R. Bergmann, Matthijs Moerland, Vincent van derWel, Saco J. deVisser, Hans Büller, Frans deLoos, Wouter S. deVries, Hans Waals, Leo G. J. deLeede, Jacobus Burggraaf, Ingrid M. C. Kamerling   +14 more
doaj   +1 more source

Halitosis in cystinosis patients after administration of immediate-release cysteamine bitartrate compared to delayed-release cysteamine bitartrate [PDF]

, 2012
Halitosis due to dimethylsulfide (DMS) generation is a major side effect of cysteamine in the treatment of cystinosis. Recently, an enteric coated formulation of cysteamine bitartrate (RP103) administered twice daily was demonstrated to be non-inferior ...
Besouw, Martine, Cornelissen, Elisabeth, Levtchenko, Elena, Rioux, Patrice, Tangerman, Albert   +4 more
core   +1 more source

Development of cysteamine loaded liposomes in liquid and dried forms for improvement of cysteamine stability

International Journal of Pharmaceutics, 2020
Despite the high aqueous solubility of cysteamine, its unpleasant organoleptic properties, hygroscopicity, instability in solutions, and poor pharmacokinetic profile are the main drawbacks that limit its use for medical and cosmetic purposes. In this study, cysteamine-loaded liposomes were prepared using the ethanol injection method.
Atallah, Carla, Greige-Gerges, Hélène, Charcosset, Catherine   +2 more
openaire   +4 more sources

Electrochemical Detection of SARS‐CoV‐2 in Saliva Using ZnO Nanorods Functionalized with Gold‐Conjugated Antireceptor‐Binding Domain Antibodies

ChemNanoMat, EarlyView.
An electrochemical immunosensor based on ZnO nanorods functionalized with gold nanoparticle‐conjugated anti‐receptor‐binding domain antibodies enables rapid, noninvasive, and selective detection of SARS‐CoV‐2 in saliva, providing a promising platform for point‐of‐care diagnostic applications.
Fabíola Lelis de Castro, Ana Cristina Honorato Castro‐Kochi, Marcos Roberto de Araújo Silva, Priscila Sabbag Ferreira, Sydney Ferreira Santos, Lídia Maria de Andrade, Mariano Venanzi, Francesca Cavalieri, Mariângela de Oliveira Silva, Isabela Pazotti Daher, Catarina Harumi Oda Ibrahim, Vivian Leite de Oliveira, Jorge Kalil, Tamires Lopes Silva, Silvia Beatriz Boscardin, Wendel Andrade Alves   +15 more
wiley   +1 more source

Advancing the Development of Subcutaneous Glucose Biosensors: Cargo‐Carrying Adhesive Biosensor Systems (CABs)

Macromolecular Bioscience, EarlyView.
A “CAB” or “cargo‐carrying adhesive biosensor” was constructed by leveraging electrostatic adhesion between an anionic hollow rod membrane (whose cavity could store a liquid optical‐assay) and cationic hydrogel caps. A final CAB was constructed from the optimal CAB wall candidate and CAB cap, and successfully retained small molecules (hydrodynamic ...
Carolina I. Martinez, Theodore S. Ferrell, Varshitha M. Krishnan, Melissa A. Grunlan   +3 more
wiley   +1 more source

PEG‐Dialdehydes/Hyperbranched Amines Based Hydrogels and their Potential as Futures Bone Adhesives

Macromolecular Materials and Engineering, EarlyView.
Different length crosslinkers are blended and used to synthesize hydrogels with the potential use as bone adhesives. With decreasing average crosslinker length, gelation time drops, while the gel strength increases. The hydrogel properties do not affect the bond strength, neither on bone nor on synthetic substrates.
Kyriakos Karakyriazis, Sebastian Stößlein, Andreas Hartwig   +2 more
wiley   +1 more source