Results 261 to 270 of about 589,705 (297)
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Journal of Structural Chemistry, 2023
The formation of salts in the l-cysteine–HNO3–H2O system was studied yielding three representatives as single crystals: anhydrous l-cysteinium nitrate (l-CysH)NO3 (I) and two new salts (l-CysH···l-Cys)NO3 (II) and (l-CysH···l-Cys)NO3∙0.5H2O (III) with the dimeric (l-CysH···l-Cys) cation.
Giester, G. +4 more
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The formation of salts in the l-cysteine–HNO3–H2O system was studied yielding three representatives as single crystals: anhydrous l-cysteinium nitrate (l-CysH)NO3 (I) and two new salts (l-CysH···l-Cys)NO3 (II) and (l-CysH···l-Cys)NO3∙0.5H2O (III) with the dimeric (l-CysH···l-Cys) cation.
Giester, G. +4 more
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1987
Publisher Summary This chapter describes the general methods are described for cysteine S-conjugates synthesis and purification with special emphasis on radiolabeled compounds. Synthesis using methanol and sodium methoxide as base is a procedure, adapted from a method for the synthesis of mercapturic acids, can be used for the synthesis of most ...
P, Hayden +3 more
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Publisher Summary This chapter describes the general methods are described for cysteine S-conjugates synthesis and purification with special emphasis on radiolabeled compounds. Synthesis using methanol and sodium methoxide as base is a procedure, adapted from a method for the synthesis of mercapturic acids, can be used for the synthesis of most ...
P, Hayden +3 more
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Progress in Neurobiology, 2020
Cysteine string protein (CSP) was discovered by use of a synapse-specific, monoclonal antibody to screen a cDNA expression library in Drosophila. A vertebrate CSP homolog was later identified and shown to co-purify with synaptic vesicles. CSP-α is now recognized as a membrane constituent of many regulated secretory organelles.
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Cysteine string protein (CSP) was discovered by use of a synapse-specific, monoclonal antibody to screen a cDNA expression library in Drosophila. A vertebrate CSP homolog was later identified and shown to co-purify with synaptic vesicles. CSP-α is now recognized as a membrane constituent of many regulated secretory organelles.
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Current Protocols in Protein Science, 1996
AbstractThis unit describes a number of methods for modifying cysteine residues of proteins and peptides by reduction and alkylation procedures. A general procedure for alkylation of cysteine residues in a protein of known size and composition with haloacyl reagents or N‐ethylmaleimide (NEM) is presented, and alternate protocols describe similar ...
M W, Crankshaw, G A, Grant
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AbstractThis unit describes a number of methods for modifying cysteine residues of proteins and peptides by reduction and alkylation procedures. A general procedure for alkylation of cysteine residues in a protein of known size and composition with haloacyl reagents or N‐ethylmaleimide (NEM) is presented, and alternate protocols describe similar ...
M W, Crankshaw, G A, Grant
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The Mechanism of Cysteine Oxygenation by Cysteine Dioxygenase Enzymes
Journal of the American Chemical Society, 2007We present here the first density functional theoretic study into the mechanism of cysteine dioxygenation by a model of cysteine dioxygenase enzymes. A large active site model containing the ligands bound to iron plus amino acid residues that are involved in hydrogen bonding interactions with the substrate is used.
Aluri, Swathi, De Visser, Sam P.
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2019
Preparation of antibody-drug conjugates (ADCs) with a highly homogeneous drug loading in general requires site-selective conjugation of a cytotoxic payload. Typically, functionality utilized for attachment of the payload is achieved through engineering of suitable chemical handles or by enzymatic modification of the antibody.
Matthew, Bird +2 more
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Preparation of antibody-drug conjugates (ADCs) with a highly homogeneous drug loading in general requires site-selective conjugation of a cytotoxic payload. Typically, functionality utilized for attachment of the payload is achieved through engineering of suitable chemical handles or by enzymatic modification of the antibody.
Matthew, Bird +2 more
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Current Protocols in Protein Science, 2017
AbstractThis unit describes a number of methods for modifying cysteine residues of proteins and peptides. A general procedure for alkylation of cysteine residues in a protein of known size and composition with haloacyl reagents or N‐ethylmaleimide (NEM) is presented, and alternate protocols describe similar procedures for use when the size and ...
openaire +2 more sources
AbstractThis unit describes a number of methods for modifying cysteine residues of proteins and peptides. A general procedure for alkylation of cysteine residues in a protein of known size and composition with haloacyl reagents or N‐ethylmaleimide (NEM) is presented, and alternate protocols describe similar procedures for use when the size and ...
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Analytical Biochemistry, 1963
Abstract A technically easy, sensitive method for specific determination of cysteine was developed. It was based upon the fact that an equimolecular reaction between cysteine and noradrenochrome caused the pink color of the latter to change to yellow, while the pink color remained unchanged or merely faded in the presence of other sulfhydryl ...
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Abstract A technically easy, sensitive method for specific determination of cysteine was developed. It was based upon the fact that an equimolecular reaction between cysteine and noradrenochrome caused the pink color of the latter to change to yellow, while the pink color remained unchanged or merely faded in the presence of other sulfhydryl ...
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