Results 321 to 330 of about 1,002,644 (386)

Uncovering protein prenylation in Th1 cells: novel prenylation sites and insights into statin and farnesyltransferase inhibition. [PDF]

BMC Biol
Koch J, Ruggia A, Beha C, Wipf I, Zhakparov D, Westermann P, Schmelzer S, Heider A, Fröhlich K, Baerenfaller K.   +9 more
europepmc   +1 more source

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

Advanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian, Chenghong Hu, Yong Xu, Wentao Xu, Zhe Wang, Wan Gan, Weiyang Tang, Lijiang Huang, Aleksandr V. Samorodov, Yi Wang   +9 more
wiley   +1 more source

Optimization of the Dark Fermentation Technique for Hydrogen Production through Supplementation with Ascorbic Acid and/or l-Cysteine by <i>Clostridium butyricum</i> CCDBC 11. [PDF]

J Agric Food Chem
Pistekova H, Dusankova M, Sopik T, Klaban J, Dostalkova J, Moucka R, Sedlarik V.   +6 more
europepmc   +1 more source

The CXCL10‐CXCR3 Axis Induces Tumor‐Associated Neutrophils to Interfere with CTLs‐Mediated Antitumor Activity in EBV‐Associated Epithelial Cancers

Advanced Science, EarlyView.
Compared with EBV‐negative epithelial cancer cells, EBV‐associated epithelial cancer cells exhibit enhanced secretion of chemokines, including CXCL10 and CCL5, to attract neutrophils. Via the CXCL10‐CXCR3 axis‐mediated positive feedback loop, neutrophils within EBV‐associated epithelial cancer cells are induced to form abundant NETs, which facilitate ...
Dijun Ouyang, Tong Xiang, Yuanyuan Chen, Mengjia Song, Jingjing Zhao, Hao Chen, Si Li, Lifeng Zhang, Chi Xu, Yan Ren, Yong Tao, Qijing Wang, Jia He, Yongqiang Li, Sisi Xie, Yuanyuan Liu, Yan Wang, Xinyi Yang, Jinqi You, Songzuo Xie, Yingzi Li, Desheng Weng, Qiuzhong Pan, Qi Yang, Jianchuan Xia   +24 more
wiley   +1 more source

Structure of the phosphocysteine intermediate of the phosphatase of regenerating liver PTP4A1. [PDF]

J Biol Chem
Mahbub L, Kozlov G, Knorn C, Gehring K.
europepmc   +1 more source

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

Advanced Science, EarlyView.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui, Xinhang Meng, Yujie Luo, Jinfeng Qian, Fengrun Sun, Mingke Qiu, Songcun Wang   +6 more
wiley   +1 more source

The Impact of Conjugation Mode and Site on Tubulysin Antibody-Drug-Conjugate Efficacy and Stability. [PDF]

ChemistryOpen
Yamazoe S, Cheng Q, Kotapati S, Rangan VS, Sung MC, Deshpande M, Jashnani A, Qiang C, Smith MJ, Pan C, Dollinger G, Rajpal A, Strop P, Rao C.   +13 more
europepmc   +1 more source

Turning the knobs: The impact of glutathionylation on starch metabolism. [PDF]

Plant Physiol
Moseler A.
europepmc   +1 more source