Results 11 to 20 of about 219,552 (223)
Frontiers in Plant Science, 2014 Programmed cell death (PCD) is a genetically determined process in all multicellular organisms. Plant PCD is effected by a unique group of papain-type cysteine endopeptidases (CysEP) with a C-terminal KDEL endoplasmic reticulum (ER) retention signal ...
Timo eHöwing +6 more
doaj +2 more sources
Two New Cysteine Endopeptidases Obtained from the Latex of Araujia hortorum Fruits
Journal of Protein Chemistry, 2001 Two new endopeptidases were purified to homogeneity from the latex of Araujia hortorum fruits by a simple purification procedure involving ultracentrifugation and ion exchange chromatography. Molecular weights of araujiain h II and araujiain h III were 23,718 and 23546 (mass spectrometry), respectively.
Obregón, Walter David +5 more
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Positional scanning and computational modeling reveal determinants of legumain transpeptidase activity. [PDF]
Protein SciAbstract Legumain is a lysosomal cysteine protease that plays a central role in antigen processing for MHC class II presentation. Beyond its canonical proteolytic activity, legumain can also function as a peptide ligase or transpeptidase. This non‐canonical activity becomes particularly relevant under pathophysiological conditions such as cancer and ...
Klaushofer R +3 more
europepmc +2 more sources
Frontiers in Cellular and Infection Microbiology, 2020 Porphyromonas gingivalis (P. gingivalis) is a keystone pathogen in periodontitis. However, several clinical studies have revealed an enrichment of P. gingivalis in the stool samples and colorectal mucosa of colorectal cancer patients.
Wenxin Mu +5 more
doaj +1 more source
Identification and Characterization of a Rice Cysteine Endopeptidase that Digests Glutelin [PDF]
European Journal of Biochemistry, 1996 Little or no endopeptidase activity was detected in extracts from storage organs of dark‐grown rice seeds until day 6 or post‐imbibition, and the activity expressed per seed increased notably after day 9, reached a maximum on day 18, then decreased.
H, Kato, T, Minamikawa
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Novel broad-spectrum activity-based probes to profile malarial cysteine proteases.
PLoS ONE, 2020 Clan CA cysteine proteases, also known as papain-like proteases, play important roles throughout the malaria parasite life cycle and are therefore potential drug targets to treat this disease and prevent its transmission. In order to study the biological
Michele S Y Tan +7 more
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Molecules, 2023 This research aimed to determine the biofunctional properties of wheat flour (WF) protein fractions and modifications to the antioxidant, anti-α-amylase and anti-angiotensin-I converting enzyme (ACE) activities induced by the action of digestive ...
Sana Gammoh +11 more
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A Boophilus microplus vitellin-degrading cysteine endopeptidase [PDF]
Parasitology, 2003 Here we describe the purification and characterization of a vitellin (VT) degrading cysteine endopeptidase (VTDCE) from eggs of the hard tick Boophilus microplus. A homogeneous enzyme preparation was obtained by chromatographic fractionation on ion-exchange and gel filtration columns and an autolysis step.
A, Seixas +6 more
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PLoS ONE, 2017 Allosteric targeting is progressively gaining ground as a strategy in drug design. Its success, however, depends on our knowledge of the investigated system.
Marko Novinec
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Bioinformatics analysis and characterization of a secretory cystatin from Thelohanellus kitauei
AMB Express, 2020 Thelohanellus kitauei, is a member of obligate parasitic myxozoans, which causes intestinal giant-cystic disease of common carp (Cyprinus carpio) and has resulted in significant economic losses in carp farms.
Fengli Zhang +8 more
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