Results 21 to 30 of about 13,055 (147)

Intracellular Porphyromonas gingivalis Promotes the Proliferation of Colorectal Cancer Cells via the MAPK/ERK Signaling Pathway

Frontiers in Cellular and Infection Microbiology, 2020
Porphyromonas gingivalis (P. gingivalis) is a keystone pathogen in periodontitis. However, several clinical studies have revealed an enrichment of P. gingivalis in the stool samples and colorectal mucosa of colorectal cancer patients.
Wenxin Mu, Yiqun Jia, Xiaobing Chen, Haoyu Li, Zhi Wang, Bin Cheng   +5 more
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Identification and Characterization of a Rice Cysteine Endopeptidase that Digests Glutelin [PDF]

European Journal of Biochemistry, 1996
Little or no endopeptidase activity was detected in extracts from storage organs of dark‐grown rice seeds until day 6 or post‐imbibition, and the activity expressed per seed increased notably after day 9, reached a maximum on day 18, then decreased.
H, Kato, T, Minamikawa
openaire   +2 more sources

Novel broad-spectrum activity-based probes to profile malarial cysteine proteases.

PLoS ONE, 2020
Clan CA cysteine proteases, also known as papain-like proteases, play important roles throughout the malaria parasite life cycle and are therefore potential drug targets to treat this disease and prevent its transmission. In order to study the biological
Michele S Y Tan, Dara Davison, Mateo I Sanchez, Bethany M Anderson, Stephen Howell, Ambrosius Snijders, Laura E Edgington-Mitchell, Edgar Deu   +7 more
doaj   +1 more source

Functional and Bioactive Properties of Wheat Protein Fractions: Impact of Digestive Enzymes on Antioxidant, α-Amylase, and Angiotensin-Converting Enzyme Inhibition Potential

Molecules, 2023
This research aimed to determine the biofunctional properties of wheat flour (WF) protein fractions and modifications to the antioxidant, anti-α-amylase and anti-angiotensin-I converting enzyme (ACE) activities induced by the action of digestive ...
Sana Gammoh, Muhammad H. Alu’datt, Mohammad N. Alhamad, Carole C. Tranchant, Taha Rababah, Doa’a Al-U’datt, Neveen Hussein, Mohammad Alrosan, Thuan-Chew Tan, Stan Kubow, Haya Alzoubi, Ali Almajwal   +11 more
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A Boophilus microplus vitellin-degrading cysteine endopeptidase [PDF]

Parasitology, 2003
Here we describe the purification and characterization of a vitellin (VT) degrading cysteine endopeptidase (VTDCE) from eggs of the hard tick Boophilus microplus. A homogeneous enzyme preparation was obtained by chromatographic fractionation on ion-exchange and gel filtration columns and an autolysis step.
A, Seixas, P C, Dos Santos, F F, Velloso, I, Da Silva Vaz, A, Masuda, F, Horn, C, Termignoni   +6 more
openaire   +2 more sources

Computational investigation of conformational variability and allostery in cathepsin K and other related peptidases.

PLoS ONE, 2017
Allosteric targeting is progressively gaining ground as a strategy in drug design. Its success, however, depends on our knowledge of the investigated system.
Marko Novinec
doaj   +1 more source

Bioinformatics analysis and characterization of a secretory cystatin from Thelohanellus kitauei

AMB Express, 2020
Thelohanellus kitauei, is a member of obligate parasitic myxozoans, which causes intestinal giant-cystic disease of common carp (Cyprinus carpio) and has resulted in significant economic losses in carp farms.
Fengli Zhang, Yalin Yang, Chenchen Gao, Yuanyuan Yao, Rui Xia, Juan Hu, Chao Ran, Zhen Zhang, Zhigang Zhou   +8 more
doaj   +1 more source

Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases

Molecules, 2018
The synthesis of racemic substituted 7-amino-5,7,8,9-tetrahydrobenzocyclohepten-6-one hydrochlorides was optimized to enhance reproducibility and increase the overall yield.
Emmanuel Salomon, Marjorie Schmitt, Anil Kumar Marapaka, Athanasios Stamogiannos, Germain Revelant, Céline Schmitt, Sarah Alavi, Isabelle Florent, Anthony Addlagatta, Efstratios Stratikos, Céline Tarnus, Sébastien Albrecht   +11 more
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Novel insights into plant defensin ingestion induced metabolic responses in the polyphagous insect pest Helicoverpa armigera

Scientific Reports, 2023
Lepidopteran insect pest Helicoverpa armigera is one of the most destructive pests of crop plants and several biotechnological approaches are being developed for its control.
Javed A. Mulla, Vaijayanti A. Tamhane
doaj   +1 more source

Characterisation of proteins in excretory/secretory products collected from salmon lice, Lepeophtheirus salmonis

Parasites & Vectors, 2018
Background The salmon louse, Lepeophtheirus salmonis, is an ectoparasitic copepod which feeds on the mucus, skin and blood of salmonid fish species. The parasite can persist on the surface of the fish without any effective control being exerted by the ...
Scott Hamilton, Kevin McLean, Sean J. Monaghan, Carol McNair, Neil F. Inglis, Hazel McDonald, Sandra Adams, Randolph Richards, William Roy, Patrick Smith, James Bron, Alasdair J. Nisbet, David Knox   +12 more
doaj   +1 more source