Results 21 to 30 of about 219,552 (223)

Family C1 cysteine proteases: Biological diversity or redundancy? [PDF]

, 2003
Recent progress in the identification and partial characterization of novel genes encoding cysteine proteases of the papain family has considerably increased our knowledge of this family of enzymes.
Brömme D., Coulombe R., Musil D., Navab R., Tepel C.   +4 more
core   +1 more source

Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases. [PDF]

, 2010
Dipeptidyl-peptidase VI from Bacillus sphaericus and YkfC from Bacillus subtilis have both previously been characterized as highly specific γ-D-glutamyl-L-diamino acid endopeptidases. The crystal structure of a YkfC ortholog from Bacillus cereus (BcYkfC)
Abdubek, Polat, Astakhova, Tamara, Axelrod, Herbert L, Bakolitsa, Constantina, Cai, Xiaohui, Carlton, Dennis, Chen, Connie, Chiu, Hsiu Ju, Chiu, Michelle, Clayton, Thomas, Das, Debanu, Deacon, Ashley M, Deller, Marc C, Duan, Lian, Ellrott, Kyle, Elsliger, Marc André, Farr, Carol L, Feuerhelm, Julie, Godzik, Adam, Grant, Joanna C, Grzechnik, Anna, Han, Gye Won, Hodgson, Keith O, Jaroszewski, Lukasz, Jin, Kevin K, Klock, Heath E, Knuth, Mark W, Kozbial, Piotr, Krishna, S Sri, Kumar, Abhinav, Lam, Winnie W, Lesley, Scott A, Marciano, David, Miller, Mitchell D, Morse, Andrew T, Nigoghossian, Edward, Nopakun, Amanda, Okach, Linda, Puckett, Christina, Reyes, Ron, Tien, Henry J, Trame, Christine B, van den Bedem, Henry, Weekes, Dana, Wilson, Ian A, Wooley, John, Wooten, Tiffany, Xu, Qingping, Yeh, Andrew   +48 more
core   +3 more sources

Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases

Molecules, 2018
The synthesis of racemic substituted 7-amino-5,7,8,9-tetrahydrobenzocyclohepten-6-one hydrochlorides was optimized to enhance reproducibility and increase the overall yield.
Emmanuel Salomon, Marjorie Schmitt, Anil Kumar Marapaka, Athanasios Stamogiannos, Germain Revelant, Céline Schmitt, Sarah Alavi, Isabelle Florent, Anthony Addlagatta, Efstratios Stratikos, Céline Tarnus, Sébastien Albrecht   +11 more
doaj   +1 more source

Novel insights into plant defensin ingestion induced metabolic responses in the polyphagous insect pest Helicoverpa armigera

Scientific Reports, 2023
Lepidopteran insect pest Helicoverpa armigera is one of the most destructive pests of crop plants and several biotechnological approaches are being developed for its control.
Javed A. Mulla, Vaijayanti A. Tamhane
doaj   +1 more source

The astacin metalloprotease moulting enzyme NAS-36 is required for normal cuticle ecdysis in free-living and parasitic nematodes [PDF]

, 2011
Nematodes represent one of the most abundant and species-rich groups of animals on the planet, with parasitic species causing chronic, debilitating infections in both livestock and humans worldwide. The prevalence and success of the nematodes is a direct
ANDREW J. BIRNIE, ANTONY P. PAGE, GILLIAN McCORMACK, GILLIAN STEPEK, Hishida, Page   +5 more
core   +1 more source

Filling the Gaps to Solve the Extensin Puzzle [PDF]

, 2018
Extensins (EXTs) are highly repetitive plant O-glycoproteins that require several post-translational modifications (PTMs) to become functional in plant cell walls.
Borassi, Cecilia, Bringas, Mauro, Capece, Luciana, Estevez, Jose Manuel, Marzol, Eliana, Rodríguez Garcia, Diana Rosa, Sede, Ana Rocío   +6 more
core   +1 more source

Proteome readjustments in the apoplastic space of Arabidopsis thaliana ggt1 mutant leaves exposed to UV-B radiation [PDF]

, 2015
Ultraviolet-B radiation acts as an environmental stimulus, but in high doses it has detrimental effects on plant metabolism. Plasma membranes represent a major target for ROS generated by this harmful radiation.
ARRIGONI, GIORGIO, FABREGA PRATS, MARTA, GIARETTA, SABRINA, Leonard Ebinezer Barnabas, MASI, ANTONIO, PIVATO, MICAELA, PRASAD, DINESH, Syed M. M. Mehdi, TRENTIN, ANNA RITA   +8 more
core   +7 more sources

Characterisation of proteins in excretory/secretory products collected from salmon lice, Lepeophtheirus salmonis

Parasites & Vectors, 2018
Background The salmon louse, Lepeophtheirus salmonis, is an ectoparasitic copepod which feeds on the mucus, skin and blood of salmonid fish species. The parasite can persist on the surface of the fish without any effective control being exerted by the ...
Scott Hamilton, Kevin McLean, Sean J. Monaghan, Carol McNair, Neil F. Inglis, Hazel McDonald, Sandra Adams, Randolph Richards, William Roy, Patrick Smith, James Bron, Alasdair J. Nisbet, David Knox   +12 more
doaj   +1 more source

A food-grade enzyme preparation with modest gluten detoxification properties. [PDF]

PLoS ONE, 2009
Celiac sprue is a life-long disease characterized by an intestinal inflammatory response to dietary gluten. A gluten-free diet is an effective treatment for most patients, but accidental ingestion of gluten is common, leading to incomplete recovery or ...
Jennifer Ehren, Belen Morón, Edith Martin, Michael T Bethune, Gary M Gray, Chaitan Khosla   +5 more
doaj   +1 more source

Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells [PDF]

, 2007
MMP-9 (matrix metalloproteinase 9) plays a critical role in tumour progression. Although the biochemical properties of the secreted form of proMMP-9 are well characterized, little is known about the function and activity of cell surface-associated proMMP-
Egea, Virginia, Jochum, Marianne, Mentele, Reinhard, Nagase, Hideaki, Pitsch, Thomas, Ries, Christian, Zahler, Stefan   +6 more
core   +1 more source