Advanced Science, EarlyView.ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen +18 more
wiley +1 more source
An exploration of the factors involved in lifestyle decisions in young people with cystic fibrosis using decision making vignettes, and the role of perceived risk in infection [PDF]
, 2010 This study explored the factors involved in lifestyle decision making in young people with Cystic Fibrosis, specifically the role of infection risk. Certain pathogens present a high risk of infection to people with Cystic Fibrosis, and can significantly
Brash, Lisa Marie
core
Screening for cystic fibrosis-related diabetes : a systematic review [PDF]
, 2012 Background Cystic fibrosis (CF) is an inherited disease that leads to damage to lungs, pancreas and other organs. Most people with CF die prematurely from lung disease, but survival has improved markedly over the decades and it is estimated that ...
P Royle +17 more
core +1 more source
Advanced Science, EarlyView.An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu +8 more
wiley +1 more source
Sputum biomarkers and the prediction of clinical outcomes in patients with cystic fibrosis. [PDF]
, 2012 Lung function, acute pulmonary exacerbations (APE), and weight are the best clinical predictors of survival in cystic fibrosis (CF); however, underlying mechanisms are incompletely understood.
Rogers, S.L. +84 more
core +1 more source
Solid tumors of the pancreas can put on a mask through cystic change
World Journal of Surgical Oncology, 2011 Background Solid pancreatic tumors such as pancreatic ductal adenocarcinoma (PDAC), solid pseudopapillary tumor (SPT), and pancreatic endocrine tumor (PET) may occasionally manifest as cystic lesions.
Heo Jin +3 more
doaj +1 more source
Cystic fibrosis genetics: from molecular understanding to clinical application
Nature reviews genetics, 2014 The availability of the human genome sequence and tools for interrogating individual genomes provide an unprecedented opportunity to apply genetics to medicine.
G. Cutting
semanticscholar +1 more source
Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing
Advanced Science, EarlyView.Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley +1 more source
An exploratory study investigating factors associated with adherence to chest physiotherapy and exercise in adults with cystic fibrosis [PDF]
, 2009 Copyright @ 2009 European Cystic Fibrosis Society. This article is available through Elsevier's Open Access Archives and covered by Elsevier's user license: http://www.elsevier.com/about/open-access/open-access-policies/oa-license-policy/elsevier-user ...
Lynn B. Myers, Myers, Lynn B., Myers, LB
core +1 more source
Monostotic fibrous dysplasia involving occipital bone: a case report and review of literature
The Pan African Medical Journal, 2014 Fibrous dysplasia (FD) is a progressive systemic bone tumour of young and it can be seen on cranial bones. FD is divided into three types according to radiological features. The second most common subtype is polyostotic subtype.
Recep Basaran +5 more
doaj +1 more source