Results 311 to 320 of about 1,105,613 (399)

An Algorithm for the Diagnosis and Management of Severe Asthma in Children and Adolescents

open access: yesAllergy, EarlyView.
ABSTRACT Severe asthma (SA) in childhood is infrequent (≈2% of all paediatric asthma), yet it drives a disproportionate share of morbidity and cost. A clear algorithm is required to distinguish difficult‐to‐treat asthma (DTA) from true SA and to guide phenotype‐driven diagnosis and therapy.
Eckard Hamelmann   +3 more
wiley   +1 more source

Microenvironment‐Driven Mast Cell Plasticity: Insights From Cytokine‐Activated Gene Signatures in Skin and Respiratory Diseases

open access: yesAllergy, EarlyView.
Primary peripheral blood‐derived human mast cells exposed to IFNγ, IL‐33, IL‐4 + IL‐13, or TGFβ develop distinct transcriptional signatures with unique functional changes including degranulation and cytokine/chemokine release. Machine learning‐defined minimal cytokine‐activated signatures (245 genes) successfully detect cytokine‐primed mast cells in ...
Chiara Tontini   +5 more
wiley   +1 more source

Low testosterone in primary infertile men is associated with a history of maternal obesity during pregnancy: Findings from a cross‐sectional study

open access: yesAndrology, EarlyView.
Abstract Background Maternal obesity increases offspring obesity risk, but limited data exist on its association with reproductive hormones in infertile males. Objectives To investigate the impact of maternal obesity during pregnancy on total testosterone levels in primary infertile men.
Fausto Negri   +14 more
wiley   +1 more source

Associations Between Socioeconomic Status and Adherence to Medications in People With Cystic Fibrosis. [PDF]

open access: yesPediatr Pulmonol
Oates GR   +10 more
europepmc   +1 more source

Prognosis After Seven Days of Veno‐Venous Extracorporeal Membrane Oxygenation Support

open access: yesArtificial Organs, EarlyView.
The hospital survival rate of patients still on V‐V ECMO after seven days was 45.1%. Survival correlates with the respiratory situation on day seven defined as points scored above the favorability margin of survival. Day 7 may be too early to predict prognosis in V‐V ECMO.
Felix A. Rottmann   +10 more
wiley   +1 more source

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