Results 41 to 50 of about 1,122,604 (303)

Six minute walk test in Italian children with cystic fibrosis aged 6 and 11

Monaldi Archives for Chest Disease, 2021
Six Minute Walk Test (6MWT) is a field exercise test widely used in clinical practice, both in adults and in pediatric patients. The primary aim of the study is to evaluate the physical performance of the subjects and compare them with the predicted ...
Diletta Innocenti, Eleonora Masi, Giovanni Taccetti, Marco Genito, Elena Balestri, Anna Rita Berghelli, Maria Antonietta Ciciretti, Francesca Collini, Patrizia Fanzaghi, Annalisa Fogazzi, Paola Leone, Riccardo Guarise   +11 more
doaj   +1 more source

Early respiratory viral infections in infants with cystic fibrosis [PDF]

, 2015
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
A Peshkin, C Castoriadis, C Hauke, C Lasch, C Mayes, C Mayes, CG Jung, CG Jung, DC Dennett, I Semetsky, I Semetsky, J Blackmore, J Campbell, J Campbell, J Cole, J Conroy, J Conroy, J Day, J Lecoq, J Parini, JC Conroy, JR Searle, JV Wertsch, K Johnstone, K Kristjansson, LA Russell-Chapin, M Currie, M Harding, M Lynch, M Merleau-Ponty, R Leitch, R Leitch, R Leitch, R Segal, RH Hopcke, S Rowland, S Walsh, T Barone, V John-Steiner, V Villate, W James, W Sorrell   +41 more
core   +1 more source

MRSA eradication of newly acquired lower respiratory tract infection in cystic fibrosis [PDF]

, 2016
UK cystic fibrosis (CF) guidelines recommend eradication of methicillin-resistant Staphylococcus aureus (MRSA) when cultured from respiratory samples.
Downey, DG, Elborn, JS, Hoeritzauer, AI, McCaughan, J, Moore, JE, Rendall, JC, Tunney, MM, Vallières, E   +7 more
core   +3 more sources

TAS2R38 is a novel modifer gene in patients with cystic fbrosis [PDF]

, 2020
The clinical manifestation of cystic fbrosis (CF) is heterogeneous also in patients with the same cystic fbrosis transmembrane regulator (CFTR) genotype and in afected sibling pairs.
Amato, F., Carnovale, V, Castaldo, A, Cernera, G, Cimbalo, C, Comegna, M, DI LULLO, ANTONELLA MIRIAM, Gelzo, M, Iacotucci, P, Raia, V, Tosco, A   +10 more
core   +1 more source

How are the ancient cystic fibrosis patients? Cystic fibrosis diagnosed over 60 years-old

Respiratory Medicine Case Reports, 2017
Background and aims: To specify the prevalence of patients diagnosed with CF at age of ≥60 year-old and to analyze their characteristics. Patients and methods: Observational study of CF patients which were diagnosed at age ≥60 year-old.
C. Prados, M. Lerín, J.J. Cabanillas, L. Gómez-Carrera, R. Álvarez-Sala, M.T. Martinez, L. Máiz, R.M. Girón, A. Solé, M. Martínez, S. Quirós   +10 more
doaj   +1 more source

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation [PDF]

, 2014
Restoration of BECN1/Beclin 1-dependent autophagy and depletion of SQSTM1/p62 by genetic manipulation or autophagy-stimulatory proteostasis regulators, such as cystamine, have positive effects on mouse models of human cystic fibrosis (CF). These measures
Amin R, Andrea Venerando, Angela Sepe, Anil Mehta, Anna Bossi, Anna Zolin, Antonella Tosco, Boyle MP BS, Carlo A Leone, Daniela De Stefano, Donaldson S., Fabiola De Gregorio, Fischer H, Gianni Bona, Gibson LE, Giuseppe De Rosa, Guido Kroemer, Illek B, Jayaraman S, Kerem B, Kerem Eithan HMO, Laura Salvadori, Legssyer R, Lorenzo A Pinna, Luigi Maiuri, Lukacs G, Maria C Maiuri, Massimo Pettoello-Mantovani, Masvidal L, Pharmaceuticals Cylene, Pharmaceuticals Cylene, Rosa Grassia, Speranza Esposito, Standardization of Spirometry, Stefano Guido, Stern M, Valeria R Villella, Valeria Raia, van Doorninck JH, Villella VR   +39 more
core   +4 more sources

Diagnostic agreement among experts assessing adults presenting with possible cystic fibrosis: need for improvement and implications for patient care

ERJ Open Research, 2022
Background Increasing awareness of milder presentations of cystic fibrosis (CF) and greater interest in non-CF bronchiectasis are likely to lead to more CF screening by respiratory clinicians. As a result, adults who may not strictly fulfil CF diagnostic
Alessandro N. Franciosi, April Tanzler, Jodi Goodwin, Pearce G. Wilcox, George M. Solomon, Albert Faro, Noel G. McElvaney, Damian G. Downey, Bradley S. Quon   +8 more
doaj   +1 more source

New era of cystic fibrosis: full mutational analysis and personalized therapy [PDF]

, 2017
Despite its apparently simple genetics, cystic fibrosis (CF) is a rather complex genetic disease. A lot of variability in the steps of the path from the cystic fibrosis transmembrane conductance regulator (CFTR ) gene to the clinical manifestations ...
Lucarelli, Marco
core   +1 more source

VX‐445–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles

New England Journal of Medicine, 2018
BACKGROUND VX‐445 is a next‐generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore Phe508del CFTR protein function in patients with cystic fibrosis when administered with tezacaftor and ivacaftor (VX‐445 ...
D. Keating, G. Marigowda, L. Burr, C. Daines, M. Mall, E. McKone, Bonnie W. Ramsey, S. Rowe, Laura A. Sass, E. Tullis, C. Mckee, S. Moskowitz, S. Robertson, J. Savage, C. Simard, F. van Goor, D. Waltz, F. Xuan, T. Young, J. Taylor-Cousar   +19 more
semanticscholar   +1 more source

Interventions for the eradication of meticillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis [PDF]

, 2015
Background: Cystic fibrosis is an inherited recessive disorder of chloride transport that is characterised by recurrent and persistent pulmonary infections from resistant organisms that result in lung function deterioration and early mortality in ...
Adeboyeku, Amelina, App, Carswell, Chambers, Chua, Chua, Coates, Conway, Cooper, Cystic Fibrosis Foundation, Dalbøge, Dasenbrook, Dasenbrook, Davis, Degg, Dodd, Dodd, Dodd, Doe, Elizur, Flume, Garske, Gee, Geller, Geller, Goldfarb, Griffith, Heininger, Hjelte, Huang, Junge, Kallen, Keel, Keller, Klevens, Labiris, Liebowitz, Lo, Loeb, Loening Baucke, Loening-Baucke, Macfarlane, Maiz, Morgan, Muhlebach, Nolan, Pai, Pearson, Postnikov, Postnikov, Quittner, Ramstrom, Ren, Roberts, Roberts, Romano, Romano, Rosenfeld, Rosenfeld, Salh, Sawicki, Serisier, Shalit, Shapera, Smith, Smyth, Solís, Stutman, Vanderhelst, Wood   +70 more
core   +4 more sources