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Reactive Oxygen Species in Cystic Kidney Disease [PDF]
AntioxidantsPolycystic kidney disease (PKD) is a rare but significant renal condition with major implications for global acute and chronic patient care. Oxidative stress and reactive oxygen species (ROS) can significantly alter its pathophysiology, clinical outcomes,
Sanat Subhash +5 more
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Baseline characteristics of the Korean genetic cohort of inherited cystic kidney disease [PDF]
Kidney Research and Clinical Practice, 2023 Background Identifying genetic mutations in individuals with inherited cystic kidney disease is necessary for precise treatment. We aimed to elucidate the genetic characteristics of cystic kidney disease in the Korean population. Methods We conducted a 3-
Jeong Min Cho +17 more
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Resident Macrophages in Cystic Kidney Disease. [PDF]
Kidney360, 2020 Interstitial inflammation is an important feature of cystic kidney disease. Renal macrophages are the most well-studied inflammatory cell in the kidney, and their involvement in cyst formation has been reported in different animal models and patients ...
Zhang Li, Kurt A. Zimmerman, B. Yoder
semanticscholar +2 more sources
Cystic Kidney Disease: A Primer
Advances in Chronic Kidney Disease, 2015 Renal cystic diseases encompass a broad group of disorders with variable phenotypic expression. Cystic disorders can present during infancy, childhood, or adulthood. Often, but not always, they can be distinguished by the clinical features including age at presentation, renal imaging characteristics, including cyst distribution, and the presence ...
Monica T. Cramer, Lisa M. Guay-Woodford
openaire +3 more sources
Journal of Clinical Medicine, 2022 Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary cystic kidney disease, with patients often having a positive family history that is characterized by a similar phenotype. However, in atypical cases, particularly those in
Akinari Sekine +30 more
semanticscholar +1 more source
BMC Nephrology, 2021 Background Inherited cystic kidney disease is a spectrum of disorders in which clusters of renal cysts develop as the result of genetic mutation. The exact methods and pipelines for defining genetic mutations of inherited cystic kidney disease are not ...
Hayne Cho Park +18 more
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Cleavage of periostin by MMP9 protects mice from kidney cystic disease.
PLoS ONE, 2023 The matrix metalloproteinase MMP9 influences cellular morphology and function, and plays important roles in organogenesis and disease. It exerts both protective and deleterious effects in renal pathology, depending upon its specific substrates.
Nabila Djaziri +5 more
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Nature Communications, 2021 Autosomal dominant polycystic kidney disease (ADPKD) is caused by germline mutations of PKD1 or PKD2 on one allele and a somatic mutation inactivating the remaining normal allele.
Hao Ding +4 more
semanticscholar +1 more source
An Empirical Biomarker-based Calculator for Autosomal Recessive Polycystic Kidney Disease - The Nieto-Narayan Formula [PDF]
, 2016 Autosomal polycystic kidney disease (ARPKD) is associated with progressive enlargement of the kidneys fuelled by the formation and expansion of fluid-filled cysts.
Goldberg, Itzhak D. +3 more
core +5 more sources
Radiological Imaging Diagnosis of Adult Renal Cystic Diseases and Management
The Iraqi Journal of Medical Sciences, 2020 Background: Renal cysts are a heterogonous group of cystic renal diseases that present in approximately 40% of the patients undergoing imaging. Objective: To describe the role of the radiological imaging methods for the diagnosis of adult renal ...
Saleh Akares, Ahmed Bahomil
doaj +1 more source