Results 1 to 10 of about 117,600 (281)

Baseline characteristics of the Korean genetic cohort of inherited cystic kidney disease [PDF]

Kidney Research and Clinical Practice, 2023
Background Identifying genetic mutations in individuals with inherited cystic kidney disease is necessary for precise treatment. We aimed to elucidate the genetic characteristics of cystic kidney disease in the Korean population. Methods We conducted a 3-
Jeong Min Cho, Hayne Cho Park, Jin Woo Lee, Hyunjin Ryu, Yong Chul Kim, Curie Ahn, Kyu-Beck Lee, Yeong Hoon Kim, Seungyeup Han, Yaerim Kim, Eun Hui Bae, Hee Gyung Kang, Eujin Park, Kyungjo Jeong, Seoon Kang, Jungmin Choi, Kook-Hwan Oh, Yun Kyu Oh   +17 more
doaj   +2 more sources

Association between lipid-lowering drug targets and the risk of cystic kidney disease: a drug-target Mendelian randomization analysis [PDF]

Renal Failure
Background Evidence regarding the causal relationship between lipid-lowering drugs and cystic kidney disease, including polycystic kidney disease (PKD), was limited.
Zhiwen Lian, Zijie Liang, Qiyan Chen, Chao Xie, Yaozhong Kong   +4 more
doaj   +2 more sources

Reactive Oxygen Species in Cystic Kidney Disease [PDF]

Antioxidants
Polycystic kidney disease (PKD) is a rare but significant renal condition with major implications for global acute and chronic patient care. Oxidative stress and reactive oxygen species (ROS) can significantly alter its pathophysiology, clinical outcomes,
Sanat Subhash, Sonya Vijayvargiya, Aetan Parmar, Jazlyn Sandhu, Jabrina Simmons, Rupesh Raina   +5 more
doaj   +2 more sources

An Empirical Biomarker-based Calculator for Autosomal Recessive Polycystic Kidney Disease - The Nieto-Narayan Formula [PDF]

, 2016
Autosomal polycystic kidney disease (ARPKD) is associated with progressive enlargement of the kidneys fuelled by the formation and expansion of fluid-filled cysts. The disease is congenital and children that do not succumb to it during the neonatal period will, by age 10 years, more often than not, require nephrectomy+renal replacement therapy for ...
Goldberg, Itzhak D., Narayan, Prakash, Nieto, Jake A., Yamin, Michael A.   +3 more
arxiv   +4 more sources

Kidney transcriptome and cystic kidney disease genes in zebrafish [PDF]

Frontiers in Physiology, 2023
Introduction: Polycystic kidney disease (PKD) is a condition where fluid filled cysts form on the kidney which leads to overall renal failure. Zebrafish has been recently adapted to study polycystic kidney disease, because of its powerful embryology and ...
Matthew Koslow, Ping Zhu, Chantal McCabe, Xiaolei Xu, Xiaolei Xu, Xueying Lin   +5 more
doaj   +2 more sources

Localized Cystic Disease of the Kidney [PDF]

American Journal of Roentgenology, 2001
Localized cystic disease of the kidney is a benign nonsurgical condition. Its imaging and clinical features are characterized and differentiated from autosomal dominant polycystic kidney disease, multilocular cystic nephroma, and cystic neoplasm.Localized cystic disease was diagnosed in 18 patients on the basis of a review of imaging studies, clinical ...
Chrystia M. Slywotzky, Morton A. Bosniak
openaire   +4 more sources

Genetic identification of inherited cystic kidney diseases for implementing precision medicine: a study protocol for a 3-year prospective multicenter cohort study

BMC Nephrology, 2021
Background Inherited cystic kidney disease is a spectrum of disorders in which clusters of renal cysts develop as the result of genetic mutation. The exact methods and pipelines for defining genetic mutations of inherited cystic kidney disease are not ...
Hayne Cho Park, Hyunjin Ryu, Yong-Chul Kim, Curie Ahn, Kyu-Beck Lee, Yeong Hoon Kim, Yunmi Kim, Seungyeup Han, Yaerim Kim, Eun hui Bae, Seong Kwon Ma, Hee Gyung Kang, Yo Han Ahn, Eujin Park, Kyungjo Jeong, Jaewon Lee, Jungmin Choi, Kook-Hwan Oh, Yun Kyu Oh   +18 more
doaj   +1 more source

Cleavage of periostin by MMP9 protects mice from kidney cystic disease.

PLoS ONE, 2023
The matrix metalloproteinase MMP9 influences cellular morphology and function, and plays important roles in organogenesis and disease. It exerts both protective and deleterious effects in renal pathology, depending upon its specific substrates.
Nabila Djaziri, Cindy Burel, Lilia Abbad, Zeineb Bakey, Rémi Piedagnel, Brigitte Lelongt   +5 more
doaj   +1 more source

Radiological Imaging Diagnosis of Adult Renal Cystic Diseases and Management

The Iraqi Journal of Medical Sciences, 2020
Background: Renal cysts are a heterogonous group of cystic renal diseases that present in approximately 40% of the patients undergoing imaging. Objective: To describe the role of the radiological imaging methods for the diagnosis of adult renal ...
Saleh Akares, Ahmed Bahomil
doaj   +1 more source

Approach to Inherited Cystic Kidney Disease

Güncel Pediatri, 2015
Cystic kidney diseases are the most frequent form of inherited kidney diseases which have different etiology, pathogenesis, clinical presentation and prognosis. Although diagnosis based on, family history, clinical presentation and imaging modalities, in
Aysel Taktak, Nilgün Çakar
doaj   +1 more source