Results 251 to 260 of about 621,963 (341)

CRISPR‐Cas9‐Generated TXNDC15 c.560delA Homozygous Mouse Model Exhibits Meckel–Gruber Syndrome Phenotype

open access: yesgenesis, Volume 64, Issue 1, February 2026.
ABSTRACT To determine whether TXNDC15 variation causes Meckel–Gruber syndrome (MKS), we assessed the pathogenicity of the frameshift variant c.560delA. A CRISPR–Cas9 generated mouse model carrying the equivalent Txndc15 c.512delA mutation was analyzed at embryonic day 15.5.
Yang Liu   +10 more
wiley   +1 more source

Health Effects of Bee Products: A Comprehensive Review

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Nutritional composition of bee products and some health effects. ABSTRACT Honey, bee pollen, propolis, bee bread, royal jelly, bee venom, beeswax, and apilarnil are among the bee‐derived products that may serve health‐related purposes, as they exhibit various biological activities such as antibacterial, antiviral, antifungal, antioxidant, anti ...
Nevin Sanlier   +2 more
wiley   +1 more source

Anticancer Molecular Mechanisms of Curcuminoids: An Updated Review of Clinical Trials

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Curcuminoids remain one of the most studied dietary polyphenols as a cancer prevention and treatment agent. Inflammation and tumor progression are related to the NF‐κB signaling pathway, which is also suppressed by curcuminoids. Curcuminoids prevent the activation of a variety of signaling pathways, including the MAPK, PI3K/Akt, and NF‐kB pathways ...
Ushna Momal   +14 more
wiley   +1 more source

Acquired cystic kidney disease

open access: yes, 2014
Fahad Alabdulghani   +2 more
openaire   +1 more source

A Comprehensive Review of Acne Treatments: Unpacking the Chemical Structures and Effective Bioactive Compounds

open access: yesHealth Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Acne vulgaris is a frequent skin disorder, affecting a large part of the population worldwide, and strongly influencing not only the physical but also the mental aspects of health. The choice of therapy for acne vulgaris is a very difficult one because the multifactorial causality of the disease and interindividual ...
Mobina Tajdari   +5 more
wiley   +1 more source

Calprotectin Is a Circulating Biomarker and Potential Therapeutic Target for Sarcopenia in Chronic Obstructive Pulmonary Disease

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Sarcopenia, an important complication of chronic obstructive pulmonary disease (COPD), is significantly associated with increased mortality. Systemic inflammation is an important trigger of COPD‐related skeletal muscle dysfunction. Calprotectin is a damage‐associated molecular pattern involved in the inflammatory response, but its ...
Liwei Liao   +9 more
wiley   +1 more source

Ift25 is not a cystic kidney disease gene but is required for early steps of kidney development. [PDF]

open access: yesMech Dev, 2018
Desai PB   +5 more
europepmc   +1 more source

Circulating Metabolites Treat Human TMJ‐OA by Eliminating Senescent Chondrocytes via the C1QBP/C1q/p14ARF Axis

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
ABSTRACT Temporomandibular joint osteoarthritis (TMJ‐OA) is a progressive degenerative disorder, for which therapeutic interventions remain limited. The disruption of metabolic homeostasis plays a critical role in the pathogenesis and advancement of TMJ‐OA.
Bowen Meng   +19 more
wiley   +1 more source

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