Results 251 to 260 of about 567,471 (395)

Defects of renal tubular homeostasis and cystogenesis in the Pkhd1 knockout

iScience
Summary: Loss of PKHD1-gene function causes autosomal recessive polycystic kidney disease (ARPKD) characterized by bilateral severely enlarged kidneys and congenital liver fibrosis requiring kidney replacement therapy most frequently during childhood ...
Julia C. Fox, Susanne T. Hahnenstein, Fatima Hassan, Andrea Grund, Dieter Haffner, Wolfgang H. Ziegler   +5 more
doaj  

Spontaneous Retroperitoneal Hemorrhage Treated With Transcatheter Arterial Embolization in a Patient With Acquired Cystic Kidney Disease: A Case Report. [PDF]

Cureus
Konno H, Nitta M, Iwafuchi Y, Oyama Y, Watanabe N.   +4 more
europepmc   +1 more source

Defining the polycystin pharmacophore through high‐throughput screening and computational biophysics

British Journal of Pharmacology, EarlyView.
An unbiased high throughput electrophysiology screen identifies potent PKD2L1 channel inhibitors with divergent chemical composition that bind to pore fenestration receptors and stabilise their inactivated state. Abstract Background and Purpose Polycystins (PKD2, PKD2L1) are voltage‐gated and Ca2+‐modulated members of the TRP family of ion channels ...
Eduardo Guadarrama, Carlos G. Vanoye, Paul G. DeCaen   +2 more
wiley   +1 more source

Familial Juvenile Hyperuricemic Nephropathy and Autosomal Dominant Medullary Cystic Kidney Disease Type 2

, 2001
Karin Dahan, Arno Fuchshuber, STAVROULA ADAMIS, Michèle Smaers, Sabine Kroiss, G Loute, Jean‐Pierre Cosyns, Friedhelm Hildebrandt, Christine Verellen‐Dumoulin, Yves Pirson   +9 more
openalex   +1 more source

Prostatic Cyst : Association with Autosomal Dominant Polycystic Kidney Disease [PDF]

, 2006
AK Hooda, Sandeep Sanga, Nikhilesh Raychaudhury, AS Narula   +3 more
openalex   +1 more source

Matching clinical and genetic data in pediatric patients at risk of developing cystic kidney disease. [PDF]

Pediatr Nephrol
Bracciamà V, Vaisitti T, Mioli F, Faini AC, Del Prever GMB, Martins VH, Camilla R, Mattozzi F, Pieretti S, Luca M, Romeo CM, Saglia C, Migliorero M, Arruga F, Carli D, Amoroso A, Lonardi P, Deaglio S, Peruzzi L.   +18 more
europepmc   +1 more source

Rapamycin and dexamethasone during pregnancy prevent tuberous sclerosis complex-associated cystic kidney disease. [PDF]

JCI Insight, 2020
Nechama M, Makayes Y, Resnick E, Meir K, Volovelsky O.   +4 more
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Bilateral renal cell carcinoma (RCC) in a patient undergoing hemodialysis for autosomal dominant polycystic kidney disease (ADPKD) manifested by spontaneous cyst rupture and hemorrhage within the cyst.

, 2001
Shigeo Negi, Kenji Yamagiwa, Takahiro Komura, Toshihiko Kashii, T. Akizawa   +4 more
openalex   +2 more sources

220. AAV Mediated Gene Transfer of Smad7 in Different Models of Cystic Kidney Diseases [PDF]

, 2006
Andrea Keppler, Barbara Leuchs, Carolin Stump, Steven Dooley, J A Kleinschmidt, Norbert Gretz   +5 more
openalex   +1 more source