Results 261 to 270 of about 621,963 (341)
Explore the key challenges and limitations in nanomedicine for biofilm treatment, from drug loading efficiency to antimicrobial resistance. ABSTRACT Antimicrobial resistance continues to rise globally, with biofilm‐associated infections intensifying the clinical burden through persistent tolerance to antibiotics and evasion of immune responses ...
Husni Farah +8 more
wiley +1 more source
Ectopic Phosphorylated Creb Marks Dedifferentiated Proximal Tubules in Cystic Kidney Disease. [PDF]
Puri P +6 more
europepmc +1 more source
Organ‐on‐a‐Chip Technology and Global Multi‐Omics: Current Applications and Future Directions
Comparative analysis of multiple cell culture models. The 3D microfluidic organ‐on‐a‐chip, which is superior to the existing models in multiple aspects, can be more conducive to new studies and discoveries related to human beings. Created with BioRender (www.biorender.com).
Xuxia Cao +7 more
wiley +1 more source
Progress in RNA‐Targeted Therapeutics for Human Diseases
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang +10 more
wiley +1 more source
ABSTRACT Background Adult cancer survivors are likely to be hospitalised with chronic illnesses, although evidence for childhood and AYA survivors is limited. Aim This study quantified hospitalisations and the costs of health services used by survivors of childhood, adolescent, and young adult (AYA) cancers with and without chronic conditions.
Doreen Nabukalu +4 more
wiley +1 more source
Abstract This article presents two clinical cases of bilateral laparoscopic ovariectomy in Dexter heifers used as leisure animals to eliminate problematic sexual behaviour. Initial standing flank laparoscopy in one heifer failed due to anatomical limitations.
Cuevas‐Ramos Gabriel +3 more
wiley +1 more source
Prolonged survival in a young Dobermann with adrenal neuroblastoma
Abstract A 1‐year‐old Dobermann presented with recurrent episodes of acute diarrhoea and weight loss starting at 5 months of age. An adrenal mass was identified via ultrasound and computed tomography, leading to adrenalectomy. A diagnosis of adrenal neuroblastoma was obtained through histopathology and immunohistochemistry.
Nataliia Ignatenko +8 more
wiley +1 more source
Abstract A 6.5‐year‐old, spayed, female dog presented in acute respiratory distress. On admission, the dog exhibited dyspnoea, bradycardia, cyanosis and gastrointestinal signs, requiring immediate intubation and mechanical ventilation. Diagnostic evaluation revealed reduced butyrylcholinesterase activity, non‐cardiogenic pulmonary oedema, elevated ...
Sarah Hefer +6 more
wiley +1 more source

