Results 271 to 280 of about 621,963 (341)
Severe anaemia secondary to duodenal adenoma in a cat
Abstract A 7‐year‐old female, spayed, domestic shorthair presented with a 24‐hour history of anorexia, lethargy and melaena. The cat was hospitalized and received treatment for hypovolemia, various electrolyte abnormalities and severe anaemia with a blood transfusion, intravenous fluids and medications.
Jocosa Yasenchack +4 more
wiley +1 more source
The Scientific Case for Animal Models: A Perspective From Musculoskeletal Researchers
ABSTRACT The National Institutes of Health (NIH) has launched a major initiative to expand human‐based New Approach Methodologies (NAMs) in biomedical research and reduce reliance on animal models. While NAMs offer powerful complementary tools, animal‐based research remains indispensable in musculoskeletal science for understanding complex cellular and
Michael Hadjiargyrou +4 more
wiley +1 more source
Abstract Objectives Valproate is a highly effective antiseizure medication but carries significant teratogenic and neurodevelopmental risks to offspring if used during pregnancy. A shared decision‐making (SDM) approach is recommended to guide clinician/patient discussions on valproate suitability for women with pregnancy potential.
Sarah Louise Griffiths +8 more
wiley +1 more source
Missense variants in TMEM17 disrupt its localization and function at the ciliary transition zone, leading to a wide range of ciliopathy phenotypes, from OFD6 and Joubert syndromes to Meckel syndrome. ABSTRACT Ciliopathies are rare genetic disorders characterized by significant genetic and phenotypic variability.
Lucile Boutaud +19 more
wiley +1 more source
A, Ohsawa, E, Higashihara
openaire +1 more source
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Current Opinion in Nephrology and Hypertension, 1997
The goal of understanding the primary defects that lead to renal cystic diseases has proved to be an elusive one, despite 3 decades of physiologic and genetic investigation. Within the past 2 years the genes responsible for type 1 and type 2 autosomal dominant polycystic kidney disease have been identified.
M D, Griffin, V E, Torres, R, Kumar
openaire +4 more sources
The goal of understanding the primary defects that lead to renal cystic diseases has proved to be an elusive one, despite 3 decades of physiologic and genetic investigation. Within the past 2 years the genes responsible for type 1 and type 2 autosomal dominant polycystic kidney disease have been identified.
M D, Griffin, V E, Torres, R, Kumar
openaire +4 more sources
Acquired cystic kidney disease
European Radiology, 2000Acquired cystic kidney disease (ACKD), also known as acquired renal cystic disease (ARCD,) occurs in patients who are on dialysis for end-stage renal disease. It is generally accepted that ACKD develops as a consequence of sustained uremia and can first manifest even before dialysis is initiated while the patient is still in chronic renal failure.
J, Tantravahi, T I, Steinman
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Der Internist, 2012
Cystic kidney diseases are clinically and genetically heterogeneous. The most important entities are autosomal-dominant and autosomal-recessive polycystic kidney diseases. The proteins encoded by the involved genes are referred to as cystoproteins, which are located predominantly in the primary cilia.
K, Zerres, N, Ortiz Brüchle
openaire +3 more sources
Cystic kidney diseases are clinically and genetically heterogeneous. The most important entities are autosomal-dominant and autosomal-recessive polycystic kidney diseases. The proteins encoded by the involved genes are referred to as cystoproteins, which are located predominantly in the primary cilia.
K, Zerres, N, Ortiz Brüchle
openaire +3 more sources

