Results 71 to 80 of about 621,963 (341)

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Tubulocystic Renal Cell Carcinoma of the Native Kidney in a Renal Transplant Recipient: A Rare Case Report

Case Reports in Nephrology, 2020
Tubulocystic renal cell carcinoma (TCC) is a rare and newly recognized variant of renal cell carcinoma, which may mimic benign cystic disease of the kidney.
Brianna Ruch, Ashley J. Limkemann, Paulo Garcia, Cameron Benedict, Gaurav Gupta, Marlon Levy, Amit Sharma   +6 more
doaj   +1 more source

Spectrum of Mutations in Pediatric Non-glomerular Chronic Kidney Disease Stages 2–5

Frontiers in Genetics, 2021
Renal hypodysplasia and cystic kidney diseases, the common non-glomerular causes of pediatric chronic kidney disease (CKD), are usually diagnosed by their clinical and imaging characteristics.
Xiaoyuan Wang, Huijie Xiao, Yong Yao, Ke Xu, Xiaoyu Liu, Baige Su, Hongwen Zhang, Na Guan, Xuhui Zhong, Yanqin Zhang, Jie Ding, Fang Wang   +11 more
doaj   +1 more source

Dual Monogenic Cystic Disease Case Report: Autosomal Dominant Polycystic Kidney Disease and Autosomal Dominant Polycystic Liver Disease

Clinical Case Reports
Autosomal dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver disease (ADPLD) are inherited cystic conditions with overlapping features but distinct genetic causes and clinical courses.
Anna Katya Brossart, Kathryn Curry, Sumit Punj, Tarek Darwish, Hossein Tabriziani   +4 more
doaj   +2 more sources

Post-treatment follow-up study of abdominal cystic echinococcosis in Tibetan communities of northwest Sichuan Province, China [PDF]

, 2011
Background: Human cystic echinococcosis (CE), caused by the larval stage of Echinococcus granulosus, with the liver as the most frequently affected organ, is known to be highly endemic in Tibetan communities of northwest Sichuan Province. Antiparasitic
A Ito, A McVie, AG Saimot, Akira Ito, C Franchi, DL Morris, Dongchuan Qiu, DP McManus, E Brunetti, E Brunetti, E Larrieu, E Ortona, GR Leggatt, H Cohen, H Wen, Hector H. Garcia, I Gadea, J Eckert, J Horton, k Vutova, L Opatrny, LA Gil-Grande, M Stojkovic, M Verastegui, MW Lightowlers, N Ben Nouir, Ning Xiao, O Doiz, P Kern, P Moro, P Venkatesan, Philip S. Craig, R Rigano, Renqing Pengcuo, RJ Horton, RJ Horton, S Ioppolo, SD Lawn, T Junghanss, T Li, T Li, T Romig, T Todorov, Tiaoying Li, W Mamuti, W Zhang, Xingwang Chen, Y Sbihi, Yasuhito Sako, ZS Pawlowski   +49 more
core   +3 more sources

Are acquired cystic kidney disease and autosomal dominant polycystic kidney disease risk factors for renal cell carcinoma in kidney transplant patients?

Journal of Nephropathology, 2012
The potent immunosuppressive agents predispose the kidney transplant patients to the development of several malignancies. Primary renal cell carcinoma (RCC) accounts 4.6% of all cancers among kidney transplant recipients, 90% in native kidneys and 10% in
B. Einollahi
semanticscholar   +1 more source

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

Rare Combination of Phenotypes of Karyomegalic Interstitial Nephritis and Autosomal Recessive Polycystic Kidney Disease in an Omani Child

Oman Medical Journal
Autosomal recessive polycystic kidney disease is one of the most prevalent inherited cystic kidney diseases in infants and children, common in highly consanguineous societies such as Oman. Karyomegalic interstitial nephritis is a rare cause of hereditary
Intisar Al Alawi, Maryam Al Shehhi, Naifain Al Kalbani, Aliya Al Hosni, Ashwaq Al Mimani, Issa Al Salmi, John A. Sayer   +6 more
doaj   +1 more source

Cystic renal‐epithelial derived induced pluripotent stem cells from polycystic kidney disease patients

Stem Cells Translational Medicine, 2020
Autosomal‐dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease, leading to kidney failure in most patients. In approximately 85% of cases, the disease is caused by mutations in PKD1.
Annegien T. Kenter, Eveline Rentmeester, Job vanRiet, Ruben Boers, Joachim Boers, Mehrnaz Ghazvini, Vanessa J. Xavier, Geert J.L.H. vanLeenders, Paul C.M.S. Verhagen, Marjan E. vanTil, Bert Eussen, Monique Losekoot, Annelies deKlein, Dorien J.M. Peters, Wilfred F.J. vanIJcken, Harmen J.G. van deWerken, Robert Zietse, Ewout J. Hoorn, Gert Jansen, Joost H. Gribnau   +19 more
doaj   +1 more source

Centrosome amplification disrupts renal development and causes cystogenesis [PDF]

, 2018
International ...
Amanda Knoten, Arquint, Astrinidis, Battini, Bettencourt-Dias, Bhaskar, Boehlke, Boletta, Brito, Brown, Burtey, Chang-Panesso, Chen, Chi, Coelho, Cosenza, Davenport, Dere, Distefano, Fisher, Ganem, Godinho, Godinho, Godinho, Goto, Habedanck, Hartman, Hendry, Hoshi, Jain, Jain, Janssen, Jinzhi Wang, Jonassen, Keefe Davis, Kobayashi, Krämer, Kulukian, Kyuhwan Shim, Lai Kuan Dionne, Levine, Lin, Ma, Mahjoub, Majumdar, Marthiens, Marthiens, Masato Hoshi, Masyuk, Moe R. Mahjoub, Mugford, Mundlos, Nano, Nigg, Nigg, Ogden, Patel, Quintyne, Renata Basto, Roselli, Saifudeen, Saifudeen, Sanjay Jain, Schmidt-Ott, Serçin, Shao, Sharma, Shillingford, Silkworth, Sillibourne, Simons, Srivastava, Takakura, Tammachote, Tao Cheng, Veronique Marthiens, Vitre, Werner, Yoder, Zhao   +79 more
core   +8 more sources