Inhibition of Low-Density Lipoprotein Oxidation by Cysteamine, Cystamine, Cysteine and Cystine at Lysosomal pH and pH 7.4. [PDF]
Parkes EJ +8 more
europepmc +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
Quantification of Single-Cell Cysteine Using an Electrochemical Nanosensor for Predicting Tumor Disulfidptosis Susceptibility. [PDF]
Zhang C +12 more
europepmc +1 more source
Kidney Stone, Nutritional Perceptions and Impact of Tea on Stone Formation
ABSTRACT The significant financial burden that urinary stone disease places on healthcare systems is only anticipated to increase over time. It is becoming more common over the globe. It is an increasing urinary condition that impacts around 12% of the global population, and environmental variables appear to be a key contributor.
Munir Ahmed +5 more
wiley +1 more source
Selenomethionine as a dual-mechanism ferroptosis inhibitor: selenium-supply-driven GPX4 biosynthesis beyond transsulfuration and reductive-capacity-mediated ROS scavenging independent of GPX4 activity. [PDF]
Xia C +7 more
europepmc +1 more source
ABSTRACT Small signaling peptides (SSPs) are important regulators of plant growth, development, and responses to biotic and abiotic stress, yet their role in the C4 grass Sorghum bicolor is largely uncharacterized. To help fill this knowledge gap, 219 sorghum genes that encode SSPs were identified based on SSP sequences previously identified in ...
Evan Kurtz, Brian McKinley, John Mullet
wiley +1 more source
Fe₃O₄@MCM-41-Cystine-ZnCl₂ nanocomposite in deep eutectic solvent: a sustainable and scalable catalytic system for three-component synthesis of triarylpyridines. [PDF]
Al Omari RH +6 more
europepmc +1 more source
Dynamic disorder is crucial for mitochondrial protein import
Abstract The import of proteins into mitochondria poses fundamental mechanistic challenges: aggregation‐prone precursor proteins must be maintained in aqueous compartments and threaded through narrow pores without becoming stuck or mislocalized. Recent evidence from mitochondrial protein import studies and other chaperone systems underscores the ...
Jakob Schneider +3 more
wiley +1 more source
Separate core-shell analysis of urinary stones may influence specific metaphylaxis. [PDF]
Winterhagen FI +4 more
europepmc +1 more source

