Mechanisms and therapeutic potential of disulphidptosis in cancer
Cell Proliferation, Volume 58, Issue 1, January 2025.SLC7A11 plays a pivotal role in tumour development by facilitating cystine import to enhance glutathione synthesis and counteract oxidative stress. Disulphidptosis, an emerging form of cell death observed in cells with high expression of SLC7A11 under glucose deprivation, is regulated through reduction–oxidation reactions and disulphide bond formation.
Yanhu Li +12 more
wiley +1 more source
Sample Preparation for Determination of Biological Thiols by Liquid Chromatography and Electromigration Techniques [PDF]
, 2004 Wydrukowano z dostarczonych Wydawnictwu UŁ gotowych materiałówMajority of the bioanalytical or environmental methods do not use just one chromatografie or electrophoretic step, but rather involve several sample pretreatment steps which simplfy the ...
Bald, Edward
core
Case Reports in Pediatrics, Volume 2025, Issue 1, 2025.Diabetic ketoacidosis (DKA) is a common initial presentation of type 1 diabetes mellitus (T1DM) in children occurring in up to 40% of cases. DKA can also be associated with severe complications, including nephrolithiasis. We present the case of a 12 years and 8‐month‐old boy who developed acute kidney injury (AKI) secondary to bilateral urinary ...
Fabio Rotondo +6 more
wiley +1 more source
Plasma membrane transport of thyroid hormones and its role in thyroid hormone metabolism and bioavailability [PDF]
, 2001 Although it was originally believed that thyroid hormones enter target cells by passive diffusion, it is now clear that cellular uptake is effected by carrier-mediated processes.
Docter, R. (Roel) +5 more
core +3 more sources
Aminosäuren – Leitlinie Parenterale Ernährung, Kapitel 4 [PDF]
, 2009 Protein catabolism should be reduced and protein synthesis promoted with parenteral nutrion (PN). Amino acid (AA) solutions should always be infused with PN. Standard AA solutions are generally used, whereas specially adapted AA solutions may be required
Blumenstein, Irina Ursula +4 more
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Electroanalytical Overview: Screen‐Printed Electrochemical Sensing Platforms
ChemElectroChem, Volume 11, Issue 19, October 1, 2024.In our paper we overview the use of screen‐printed electrode focusing on metallic and bulk modified varieties, geometric changes (micro, microband and associated arrays), electrode activation and finally the physical length of screen‐printed electrodes, providing insights for future research.
Robert D. Crapnell, Craig E. Banks
wiley +1 more source
Epidemiology of paediatric renal stone disease: a 22-year single centre experience in the UK [PDF]
, 2017 BACKGROUND: Whilst still rare, the incidence of paediatric stone disease is increasing in developed countries and it is important to evaluate the aetiology.
Bockenhauer, D +5 more
core +1 more source
Clinical Characteristics and In Silico Analysis of Cystinuria Caused by a Novel SLC3A1 Mutation [PDF]
, 2022 Lexin Liu +7 more
openalex +1 more source
Customizing carrier screening in the Chinese population: Insights from a 334‐gene panel
Prenatal Diagnosis, Volume 44, Issue 11, Page 1335-1343, October 2024.Abstract Objective This study aimed to evaluate the yield and applicability of expanded carrier screening and propose carrier rate screening thresholds suitable for the Chinese population by comparing the current screening panel with the American College of Medical Genetics and Genomics recommended panel of 113 genes.
Sha Liu +11 more
wiley +1 more source
α-Lipoic Acid (ALA) Improves Cystine Solubility in Cystinuria: Report of 2 Cases
Pediatrics, 2020 In this study, we report beneficial effects of a nutritional supplement (ALA) in improving cystine solubility and reducing kidney stone burden in 2 pediatric patients with cystinuria.
Onur Cil, Farzana Perwad
semanticscholar +1 more source