Results 81 to 90 of about 431 (97)

Identification of an oxytocinase/vasopressinase-like leucyl-cystinyl aminopeptidase (LNPEP) in teleost fish and evidence for hypothalamic mRNA expression linked to behavioral social status

General and Comparative Endocrinology, 2017
The vasotocin/vasopressin and isotocin/mesotocin/oxytocin family of nonapeptides regulate social behaviors and physiological functions associated with reproductive physiology and osmotic balance. While experimental and correlative studies provide evidence for these nonapeptides as modulators of behavior across all classes of vertebrates, mechanisms for
Sean C Lema
exaly   +4 more sources

Cystinyl Aminopeptidase/Oxytocinase

, 2013
Masafumi Tsujimoto, Shigehiko Mizutani
exaly   +3 more sources

Cystinyl aminopeptidase, oxytocinase and insulin-regulated aminopeptidase

, 2004
Masafumi Tsujimoto, Shigehiko Mizutani
exaly   +3 more sources

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Angiotensin AT4 receptor ligand interaction with cystinyl aminopeptidase and aminopeptidase N: [125I]Angiotensin IV only binds to the cystinyl aminopeptidase apo-enzyme

European Journal of Pharmacology, 2006
Due to its high affinity for [(125)I]Angiotensin IV, cystinyl aminopeptidase (CAP) has recently been assigned as the 'angiotensin AT(4) receptor'. Since the aminopeptidase N (AP-N) activity is also susceptible to inhibition by Angiotensin IV, it might represent an additional target for this peptide. Based on [(125)I]Angiotensin IV binding and catalytic
Heidi Demaegdt, Ken Kersemans, Yvette Michotte   +2 more
exaly   +3 more sources

Synergistic modulation of cystinyl aminopeptidase by divalent cation chelators

Biochemical Pharmacology, 2004
Membranes of Chinese hamster ovary (CHO-K1) cells were used to study the opposite modulation of enzyme activity and [125I]Ang IV binding to cystinyl aminopeptidase (EC 3.4.11.3) by divalent cation chelators. Whereas ethylene diamine tetraacetic acid (EDTA) or ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid (EGTA) alone only slightly ...
Heidi Demaegdt, Veerle Kersemans, Yvette Michotte   +2 more
exaly   +4 more sources

Endogenous cystinyl aminopeptidase in Chinese hamster ovary cells: characterization by [125I]Ang IV binding and catalytic activity

Biochemical Pharmacology, 2004
The angiotensin II C-terminal hexapeptide fragment angiotensin IV (Ang IV) exerts central and cardiovascular effects. Cystinyl aminopeptidase (EC 3.4.11.3), a membrane-associated zinc-dependent metallopeptidase of the M1 family, has recently been found to display high affinity for Ang IV and it was proposed to represent the AT4 receptor.
Heidi Demaegdt, Patrick Vanderheyden, Veerle Kersemans   +2 more
exaly   +4 more sources

Ectodomain Shedding of Cystinyl Aminopeptidase from Human Placental Membranes

Placenta, 2002
Cystinyl aminopeptidase (CAP; EC 3.4.11.3) is an integral protein of the placental membrane that is also found in a soluble form in maternal serum during pregnancy. CAP was found to be shed from human placental membranes in a temperature- and time-dependent process.
Nigel M Hooper
exaly   +3 more sources

Cystinyl aminopeptidase activity is decreased in renal cell carcinomas

Regulatory Peptides, 2007
The involvement of peptidases in carcinogenetic processes of several tumor types has been researched in recent years. Although kidney is one of the major tissues known to express cystinyl-aminopeptidase (CAP), little is known about its role in renal neoplasia.
Gorka Larrinaga, JOSÉ I Lopez, Lorena Blanco   +2 more
exaly   +3 more sources

Cystinyl aminopeptidase (oxytocinase)

Masafumi Tsujimoto, Yoshikuni Gotō
exaly   +2 more sources

Evaluation of enzyme inhibitors of cystinyl aminopeptidase and application to the measurement of immunoreactive atrial natriuretic peptide in human pregnancy

Clinica Chimica Acta, 1994
P H Baylis, J M Davison
exaly   +3 more sources