Results 31 to 40 of about 39,975 (214)

Under‐Urine‐Adhered Supramolecular Hydrogel with Linearly Sustained Quercetin Release Facilitates Hemorrhagic Cystitis Healing via Inflammation Regulation

Advanced Science, EarlyView.
A supramolecular gelatin‐based hydrogel adhesive was engineered for hemorrhagic cystitis management. It provides robust wet‐tissue adhesion, rapid hemostasis, sustained quercetin release, effectively restoring the bladder barrier via anti‐inflammatory and antioxidant actions.
Xu Cao, Hua Zhang, Yang Luo, Yaoqi Chen, Jie Yao, Renhao Ni, Tong Zhu, Yudong Yao, Jun Chen, Baolin Guo, Kerong Wu   +10 more
wiley   +1 more source

Molecular Mechanisms and Key Processes in Interstitial, Hemorrhagic and Radiation Cystitis

Biology, 2022
Cystitis is a bladder disease with a high rate of prevalence in the world population. This report focuses on Interstitial Cystitis (IC), Hemorrhagic Cystitis (HC) and Chronic Radiation Cystitis. These pathologies have different etiologies, but they share
Clément Brossard, Anne-Charlotte Lefranc, Anne-Laure Pouliet, Jean-Marc Simon, Marc Benderitter, Fabien Milliat, Alain Chapel   +6 more
doaj   +1 more source

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

Advanced Science, EarlyView.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai, Tuhina Mitra, Tanmoy Pain, Jyotiprakash Mallick, Rwiddhi Chakraborty, Kallam Tejaswi, Swagata Ghatak, Sanjib Kar   +7 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Gut microbiota and interstitial cystitis: exploring the gut-bladder axis through mendelian randomization, biological annotation and bulk RNA sequencing

Frontiers in Immunology
BackgroundSeveral observational studies have indicated an association between interstitial cystitis and the composition of the gut microbiota; however, the causality and underlying mechanisms remain unclear.
Chaowei Fu, Yu Zhao, Xiang Zhou, Jing Lv, Shengkai Jin, Yuhua Zhou, Fengping Liu, Ninghan Feng, Ninghan Feng   +8 more
doaj   +1 more source

Hemorrhagic cystitis in children treated with alkylating agent cyclophosphamide: The experience of a medical center in Taiwan

Journal of the Formosan Medical Association, 2015
Hemorrhagic cystitis is a common complication with chemotherapeutic alkylating agents. We investigated the possible prognostic factors of cyclophosphamide-induced hemorrhagic cystitis in children.
Ching-Chia Wang, Te-I Weng, Meng-Yao Lu, Rong-Sen Yang, Kai-Hsin Lin, Mei-Hwan Wu, Shing-Hwa Liu   +6 more
doaj   +1 more source

Bladder outlet obstruction secondary to posterior urethral cystitis cystica & glandularis in a 12-year-old boy. A rare case scenario

Urology Case Reports, 2020
Urethral cystitis cystica and cystitis glandularis in children are extremely rare condition. Mainly manifested as weak urine flow. Other symptoms may occur, such as terminal hematuria, urgency, frequency, and urinary incontinence.
Abdelazim Abasher, MD, Ali Abdel Raheem, MD, PhD, Rakan Aldarrab, MD, Mohammed Aldurayhim, MD, Azza Attallah, MD, Omaya Banihani, MD   +5 more
doaj   +1 more source

Case Report: Emphysematous Cystitis and Pyelonephritis Induced by Uterine Prolapse in a Subject With Untreated Diabetes Mellitus

Frontiers in Medicine, 2021
Type 2 diabetes mellitus (T2DM) is often accompanied by a lot of complications due to chronic hyperglycemia and inflammation. Emphysematous cystitis and pyelonephritis are rare types of urinary tract infections and are often complicated with DM.
Hideyuki Iwamoto, Takatoshi Anno, Haruka Takenouchi, Kaio Takahashi, Megumi Horiya, Yukiko Kimura, Fumiko Kawasaki, Kohei Kaku, Koichi Tomoda, Shinya Uehara, Hideaki Kaneto   +10 more
doaj   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Notch1 Signaling Contributes to Mechanical Allodynia Associated with Cyclophosphamide-Induced Cystitis by Promoting Microglia Activation and Neuroinflammation

Mediators of Inflammation, 2021
Aims. Notch1 signaling regulates microglia activation, which promotes neuroinflammation. Neuroinflammation plays an essential role in various kinds of pain sensation, including bladder-related pain in bladder pain syndrome/interstitial cystitis (BPS/IC).
Jialiang Chen, Honglu Ding, Bolong Liu, Xiangfu Zhou, Xin Zhou, Zhijun Lin, Fei Yang, Hailun Zhan, Hengjun Xiao   +8 more
doaj   +1 more source