Results 61 to 70 of about 39,975 (214)

Blocking α2δ-1 Subunit Reduces Bladder Hypersensitivity and Inflammation in a Cystitis Mouse Model by Decreasing NF-kB Pathway Activation

Frontiers in Pharmacology, 2019
Bladder pain is frequently associated with bladder inflammation, as in conditions like interstitial cystitis (IC), for which current analgesic therapies have limited efficacy.
Ludivine Boudieu, Ludivine Boudieu, Sarah Mountadem, Sarah Mountadem, Amandine Lashermes, Amandine Lashermes, Mathieu Meleine, Mathieu Meleine, Lauriane Ulmann, Lauriane Ulmann, François Rassendren, François Rassendren, Youssef Aissouni, Youssef Aissouni, Benoit Sion, Benoit Sion, Frédéric Antonio Carvalho, Frédéric Antonio Carvalho, Denis Ardid, Denis Ardid   +19 more
doaj   +1 more source

Bladder Function and Safety of Vibegron in Men With Overactive Bladder Receiving Treatment for Benign Prostatic Hyperplasia: Outcomes From the Phase 3 Randomized Controlled COURAGE Trial

Neurourology and Urodynamics, EarlyView.
ABSTRACT Purpose Vibegron was associated with improvements in efficacy versus placebo and was well tolerated in men with overactive bladder (OAB) on pharmacotherapy for benign prostatic hyperplasia (BPH) in the COURAGE trial (NCT03902080). Additional safety, bladder function, and urodynamics data are provided.
Eric S. Rovner, Janet Owens‐Grillo, Elizabeth Thomas, Sender Herschorn, Kenneth M. Peters, David Staskin, Salim Mujais   +6 more
wiley   +1 more source

Impact of COVID‐19 and Vaccination on Lower Urinary Tract Symptoms: Insights From a Prospective Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To evaluate the prevalence, clinical course, and risk factors of lower urinary tract symptoms (LUTS) in patients hospitalized with COVID‐19, and to assess associations with comorbidities, disease severity, and vaccination status. Methods We conducted a prospective cohort study of adult patients hospitalized with confirmed COVID‐19, who ...
Julia Duarte de Souza, Jose de Bessa Jr., Natássia Cristina Carboni Truzzi, Carolina Trigo Rocha, Bruno Camargo Rocha Paim de Araujo, Julyana Kanate Mazzoni Moromizato, Thulio Bosi Vieira Brandão, Rachel Mazoni Costa, Marcelo Hisano, Zein Mohamed Sammour, Homero Bruschini, William Carlos Nahas, Cristiano Mendes Gomes   +12 more
wiley   +1 more source

Qualitative study on shared decision making in cystitis management in general practice

BJGP Open
Background: Cystitis is commonly treated with antibiotics, although non-antibiotic options could be considered for healthy non-pregnant women. Shared decision making (SDM) can be used in cystitis management to discuss the various treatment options but ...
Tessa MZXK van Horrik, Annelies Colliers, Marco H Blanker, Eefje GPM de Bont, Antoinette A van Driel, Bart J Laan, Suzanne E Geerlings, Roderick P Venekamp, Sibyl Anthierens, Tamara N Platteel   +9 more
doaj   +1 more source

Chiropractic spinal manipulative therapy versus physical therapist‐led exercise and the risk of cauda equina syndrome in adults with lumbar disc herniation, stenosis, or radiculopathy

PM&R, EarlyView.
Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager, Anthony N. Baumann, Romeo‐Paolo T. Perfecto, Christine M. Goertz   +3 more
wiley   +1 more source

Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation

Small, EarlyView.
Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Anke Schmidt, Meike Heuser, Paul Schulan, Lea Miebach, Alice Martinet, Marcus Frank, Kristian Wende, Sander Bekeschus   +7 more
wiley   +1 more source

Multiscale Engineering of Ion‐Conducting Gels for Sustainable Bioelectronic Systems

Small Methods, EarlyView.
This review highlights multiscale engineering strategies for ion‐conducting gels aimed at achieving sustainable bioelectronic systems. It systematically examines material‐level, device‐level, and system‐level approaches to ensure long‐term stability and functional integrity under physiological conditions, integrating molecular design, device ...
Ji Hong Kim, Won Hyuk Choi, Jong Hwi Kim, Yoseph Park, Seonghwan Yun, Tae‐il Kim, Do Hwan Kim   +6 more
wiley   +1 more source

Pre‐Existing Nocturia Status Predicts Bladder Symptom Exacerbation Following COVID‐19 Vaccination in Women

The Kaohsiung Journal of Medical Sciences, EarlyView.
Hsien‐Che Ou, Hao‐Wei Chen, Yung‐Shun Juan, Yu‐Chen Chen   +3 more
wiley   +1 more source

The Evaluation and Management of Interstitial Cystitis/Bladder Pain Syndrome

European Medical Journal Urology, 2019
Interstitial cystitis or bladder pain syndrome is a frustrating symptom complex for both the patient and the clinician. Classic Hunner’s lesion interstitial cystitis is clearly a bladder disease and treating the bladder improves symptoms.
Samantha Kraemer, Brett Watson, Kenneth M Peters   +2 more
doaj  

Outcomes from an intervention study implementing fee‐free culture and susceptibility urine testing in dogs and cats

Veterinary Record, EarlyView.
Abstract Background Urine culture and susceptibility (C&S) testing is important to confirm the presence of infection and aid in antimicrobial selection to ensure that the most appropriate drug is used. Veterinarians often cite the cost of C&S as a prohibitive factor limiting its uptake.
Amy W. Hii, James R. Gilkerson, Kirsten E. Bailey, Ri Scarborough, Anna E. Sri, Magdoline Awad, Lynsey Etheridge, Laura Y. Hardefeldt   +7 more
wiley   +1 more source