The idarubicin–bovine serum albumin interaction was comprehensively investigated using multispectroscopic techniques and molecular docking. The results reveal concentration‐dependent binding, conformational changes in BSA, and static quenching behavior, supported by UV–Vis, fluorescence, FT‐IR, and DLS analyses, confirming stable complex formation ...
Mehmetcan Bilkay +4 more
wiley +1 more source
GATA2 Mutations Predict Poor Prognosis in Transplanted Myeloid Neoplasms
ABSTRACT Background GATA binding protein 2 (GATA2) plays a crucial role in the differentiation, proliferation, and maintenance of hematopoietic stem cells (HSCs). GATA2 mutations have been identified in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), but the impact of somatic GATA2 mutations on prognosis remains controversial ...
Xian Zhang +8 more
wiley +1 more source
Green TLC-densitometric method for determination of cytarabine and granisetron in spiked human plasma: optimization and whiteness assessment. [PDF]
Tohamy SI +4 more
europepmc +1 more source
Racial, Ethnic, and Neighborhood Disparities in Acute Kidney Injury in Pediatric Acute Leukemia
This multicenter retrospective cohort study describes racial, ethnic, and neighborhood disparities in acute kidney injury in pediatric patients with acute lymphoblastic/acute myeloid leukemia using electronic health record data. Racial and ethnic disparities were present after controlling for clinical factors.
Wendy C. Bravo +12 more
wiley +1 more source
Corneal epithelial microcysts due to high dose Cytarabine administration in acute myeloid leukemia
Tuba Hilkay Karapınar +7 more
doaj +1 more source
Fixed-duration cytarabine consolidation improves relapse-free survival over indefinite AZA-VEN in younger AML. [PDF]
Swain RN +9 more
europepmc +1 more source
TP53 and decitabine in acute myeloid leukemia and myelodysplastic syndromes [PDF]
et al, +8 more
core +2 more sources
ABSTRACT The central nervous system (CNS) is the most common site of extramedullary relapse in acute lymphoblastic leukemia (ALL). However, the diagnosis may be challenging due to its protean manifestations. A 64‐year‐old male reported right‐sided hearing loss with intermittent bilateral occipitotemporal headaches during a clinic follow‐up for Ph + B ...
Jun Yen Ng +3 more
wiley +1 more source
2g/m2 Ara-c induced more favorable outcome than 1g/m2 Ara-c in CLAG treatment for refractory or relapsed acute myeloid leukemia without increase toxicity: a multicenter propensity score matching analysis. [PDF]
Liu N +12 more
europepmc +1 more source
ABSTRACT Germline GATA2 deficiency predisposes to bone marrow failure, myeloid neoplasia, and immune dysregulation. The syndrome is often complicated by infection with intracellular pathogens and viruses, autoimmunity, and inflammation. Hemophagocytic lymphohistiocytosis (HLH) is a rare occurrence that can present further management challenges.
Harry Wilson +3 more
wiley +1 more source

