Results 121 to 130 of about 43,704 (225)
Schematic overview of the synergistic anticancer mechanism between Streptococcus thermophilus Ab.342 SH and Cytarabine (CYT) (Ara‐C) in A549 human lung adenocarcinoma cells. The probiotic strain, isolated from traditional dairy samples collected in Fars Province, was cultured to obtain its cell‐free supernatant (CFS) containing bioactive metabolites ...
Abbas Asoudeh‐Fard +7 more
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Intensive Induction in AML in the Era of Venetoclax: A Standing Count for “7 + 3”?
American Journal of Hematology, Volume 101, Issue 8, Page 1783-1789, August 2026.
Sudhir Tauro, Ayalew Tefferi
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Abstract We conducted a prospective, multicenter, Phase II study to evaluate the safety and efficacy of venetoclax/azacitidine/low‐dose cytarabine/aclarubicin/granulocyte colony‐stimulating factor (G‐CSF) (VA‐CAG) in young patients with newly diagnosed acute myeloid leukemia (ND‐AML). The VA‐CAG regimen included venetoclax (100 mg/day, Days 1–2; 200 mg,
Xiaoping Li +36 more
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ABSTRACT Hyperleukocytosis in acute myeloid leukemia (AML) could cause life‐threatening complications, including leukostasis and tumor lysis syndrome (TLS). While leukocytapheresis and continuous renal replacement therapy (CRRT) are typically performed independently to maintain hemodynamic stability and manage anticoagulation, their simultaneous ...
Seung Hee Cho +7 more
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ABSTRACT Introduction Primary CNS lymphoma (PCNSL) is treated with intensive chemotherapy and autologous stem cell transplant (HDT‐ASCT), yet up to one‐third of patients relapse. Standard MRI response criteria may not reliably distinguish residual tumour from post‐treatment change; additional MRI sequences, such as apparent diffusion coefficient (ADC),
Dewen Meng +4 more
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Peripheral T-cell Lymphoma in Japan: Real-World Patient Characteristics, Treatment Patterns, Healthcare Resource Utilization, and Costs. [PDF]
Dharmani C +7 more
europepmc +1 more source
ABSTRACT Acute myeloid leukemia (AML) is an aggressive hematologic malignancy associated with a high risk of relapse. Leukemia cutis is characterized by the presence of neoplastic leukocytes infiltrating the skin. Here, we present a previously treated AML patient who relapsed with isolated leukemia cutis without bone marrow involvement. Fluorescence in
Bana Antonios +9 more
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ABSTRACT CPX‐351 is associated with reduced non‐hematologic toxicity, but its cardiac safety is not well defined. We prospectively assessed ejection fraction (EF) and global longitudinal strain (GLS) in younger adults with AML treated with a single CPX‐351‐based induction. Median changes were mild and comparable to standard “7 + 3”.
Chezi Ganzel +7 more
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Cooling immunochemotherapy and hematopoietic stem cell transplantation for refractory systemic epstein-barr virus-positive T-cell lymphoma in children: a single institution experience. [PDF]
Kim BK +4 more
europepmc +1 more source
Nucleotide Metabolism in Health and Disease
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao +7 more
wiley +1 more source

