Results 121 to 130 of about 43,704 (225)

Synergistic Anti‐Lung Cancer Effects of Cytarabine and a NCBI‐Registered Streptococcus via Modulation of Apoptotic and Survival Pathways

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
Schematic overview of the synergistic anticancer mechanism between Streptococcus thermophilus Ab.342 SH and Cytarabine (CYT) (Ara‐C) in A549 human lung adenocarcinoma cells. The probiotic strain, isolated from traditional dairy samples collected in Fars Province, was cultured to obtain its cell‐free supernatant (CFS) containing bioactive metabolites ...
Abbas Asoudeh‐Fard   +7 more
wiley   +1 more source

Intensive Induction in AML in the Era of Venetoclax: A Standing Count for “7 + 3”?

open access: yes
American Journal of Hematology, Volume 101, Issue 8, Page 1783-1789, August 2026.
Sudhir Tauro, Ayalew Tefferi
wiley   +1 more source

Venetoclax plus azacitidine, low‐dose cytarabine, aclarubicin, and G‐CSF (VA‐CAG regimen) for newly diagnosed young patients with acute myeloid leukemia: A prospective, multicenter, single‐arm Phase II clinical trial

open access: yesHemaSphere, Volume 10, Issue 8, August 2026.
Abstract We conducted a prospective, multicenter, Phase II study to evaluate the safety and efficacy of venetoclax/azacitidine/low‐dose cytarabine/aclarubicin/granulocyte colony‐stimulating factor (G‐CSF) (VA‐CAG) in young patients with newly diagnosed acute myeloid leukemia (ND‐AML). The VA‐CAG regimen included venetoclax (100 mg/day, Days 1–2; 200 mg,
Xiaoping Li   +36 more
wiley   +1 more source

Simultaneous Leukocytapheresis and Continuous Renal Replacement Therapy for Acute Myeloid Leukemia: A Case Report

open access: yesJournal of Clinical Apheresis, Volume 41, Issue 4, August 2026.
ABSTRACT Hyperleukocytosis in acute myeloid leukemia (AML) could cause life‐threatening complications, including leukostasis and tumor lysis syndrome (TLS). While leukocytapheresis and continuous renal replacement therapy (CRRT) are typically performed independently to maintain hemodynamic stability and manage anticoagulation, their simultaneous ...
Seung Hee Cho   +7 more
wiley   +1 more source

MRI Predictors of Outcome in Primary Central Nervous System Lymphoma Patients Before and After Autologous Stem Cell Transplant

open access: yeseJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Introduction Primary CNS lymphoma (PCNSL) is treated with intensive chemotherapy and autologous stem cell transplant (HDT‐ASCT), yet up to one‐third of patients relapse. Standard MRI response criteria may not reliably distinguish residual tumour from post‐treatment change; additional MRI sequences, such as apparent diffusion coefficient (ADC),
Dewen Meng   +4 more
wiley   +1 more source

Salvage With Revumenib: Targeting KMT2A‐Rearranged Isolated Leukemia Cutis Identified in the Extramedullary Disease

open access: yeseJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Acute myeloid leukemia (AML) is an aggressive hematologic malignancy associated with a high risk of relapse. Leukemia cutis is characterized by the presence of neoplastic leukocytes infiltrating the skin. Here, we present a previously treated AML patient who relapsed with isolated leukemia cutis without bone marrow involvement. Fluorescence in
Bana Antonios   +9 more
wiley   +1 more source

Subclinical Cardiac Changes Following CPX‐351 Induction in Adults with Favorable/Intermediate‐Risk AML

open access: yeseJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT CPX‐351 is associated with reduced non‐hematologic toxicity, but its cardiac safety is not well defined. We prospectively assessed ejection fraction (EF) and global longitudinal strain (GLS) in younger adults with AML treated with a single CPX‐351‐based induction. Median changes were mild and comparable to standard “7 + 3”.
Chezi Ganzel   +7 more
wiley   +1 more source

Nucleotide Metabolism in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao   +7 more
wiley   +1 more source

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