Results 1 to 10 of about 36,964 (190)

Potential effects of pomegranate on lipid peroxidation and pro-inflammatory changes in daunorubicin-induced cardiotoxicity in rats

open access: yesInternational Journal of Preventive Medicine, 2016
Background: Daunorubicin-induced acute cardiotoxicity caused by oxidative stress and free radical formation. Pomegranate possessed a significant in vitro free radical scavenging activity.
Hayder M Al-Kuraishy, Ali I Al-Gareeb
doaj   +1 more source

A Microbiota-Dependent Response to Anticancer Treatment in an In Vitro Human Microbiota Model: A Pilot Study With Hydroxycarbamide and Daunorubicin

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
BackgroundAnticancer drug efficacy is linked to the gut microbiota’s composition, and there is a dire need to better understand these interactions for personalized medicine.
Claire Amaris Hobson   +12 more
doaj   +1 more source

Protective Effects of Royal Jelly on the Reproductive System of Male Mice Treated with Daunorubicin

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان, 2022
Background and Aim: Daunorubicin is an effective antibiotic for the chemotherapy of various cancers. To prevent damage to healthy cells during chemotherapy, it is recommended to change this treatment or protect healthy cells from chemotherapeutic agents ...
Mansour Safaei Pourzamani   +4 more
doaj  

The Study on Electrochemical Behaviors of the Interactions between Daunorubicin Hydrochloride and BSA

open access: yesNano Biomedicine and Engineering, 2010
The Electrochemical behaviors of Daunorubicin hydrochloride, and the interactions between Daunorubicin hydrochloride and BSA, were studied in this paper, with Linear sweep voltammetry and Cyclic voltammety methods.
Jie Liu, Bo Zhang
doaj   +1 more source

Modulation of caveolins, integrins and plasma membrane repair proteins in anthracycline-induced heart failure in rabbits.

open access: yesPLoS ONE, 2017
Anthracyclines are chemotherapeutic drugs known to induce heart failure in a dose-dependent manner. Mechanisms involved in anthracycline cardiotoxicity are an area of relevant investigation.
Yasuhiro Ichikawa   +8 more
doaj   +1 more source

Melt electrospinning of daunorubicin hydrochloride-loaded poly (ε-caprolactone) fibrous membrane for tumor therapy

open access: yesBioactive Materials, 2017
Daunorubicin hydrochloride is a cell-cycle non-specific antitumor drug with a high therapeutic effect. The present study outlines the fabrication of daunorubicin hydrochloride-loaded poly (ε-caprolactone) (PCL) fibrous membranes by melt electrospinning ...
He Lian, Zhaoxu Meng
doaj   +1 more source

Altered Pharmacokinetics of Daunorubicin in Rats with CCl4-Induced Hepatic Injury

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2007
PURPOSE. The effect of CCl4-induced experimental hepatic injury (CCl4-EHI) on the pharmacokinetics of daunorubicin was investigated systemically in rats, in an attempt to elucidate the major determinants of the effect of CCl4-EHI on the pharmacokinetics ...
Min-Koo Choi   +4 more
doaj   +1 more source

Time dependent response of daunorubicin on cytotoxicity, cell cycle and DNA repair in acute lymphoblastic leukaemia

open access: yesBMC Cancer, 2019
Background Daunorubicin is commonly used in the treatment of acute lymphoblastic leukaemia (ALL). The aim of this study was to explore the kinetics of double strand break (DSB) formation of three ALL cell lines following exposure to daunorubicin and to ...
Hussain Mubarak Al-Aamri   +5 more
doaj   +1 more source

Alternating electric fields can improve chemotherapy treatment efficacy in blood cancer cell U937 (non-adherent cells)

open access: yesBMC Cancer, 2023
Background Recent achievements in cancer therapy are the use of alternating electrical fields at intermediate frequencies (100–300 kHz) and low intensities (1–3 V/cm), which specifically target cell proliferation while affecting different cellular ...
Elham Homami   +3 more
doaj   +1 more source

ATP Release from Chemotherapy-Treated Dying Leukemia Cells Elicits an Immune Suppressive Effect by Increasing Regulatory T Cells and Tolerogenic Dendritic Cells

open access: yesFrontiers in Immunology, 2017
Chemotherapy-induced immunogenic cell death can favor dendritic cell (DC) cross-priming of tumor-associated antigens for T cell activation thanks to the release of damage-associated molecular patterns, including ATP.
Mariangela Lecciso   +17 more
doaj   +1 more source

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