Frontiers in Cellular and Infection Microbiology, 2022 BackgroundAnticancer drug efficacy is linked to the gut microbiota’s composition, and there is a dire need to better understand these interactions for personalized medicine.
Claire Amaris Hobson +12 more
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Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response. [PDF]
, 2016 Adipocytes promote cancer progression and impair treatment, and have been shown to protect acute lymphoblastic leukemia (ALL) cells from chemotherapies. Here we investigate whether this protection is mediated by changes in oxidative stress.
Behan, James W +6 more
core +1 more source
Protective Effects of Royal Jelly on the Reproductive System of Male Mice Treated with Daunorubicin
مجله علمی دانشگاه علوم پزشکی کردستان, 2022 Background and Aim: Daunorubicin is an effective antibiotic for the chemotherapy of various cancers. To prevent damage to healthy cells during chemotherapy, it is recommended to change this treatment or protect healthy cells from chemotherapeutic agents ...
Mansour Safaei Pourzamani +4 more
doaj
The synthesis and characterization of polypeptide-adriamycin conjugates and its complexes with adriamycin. Part I [PDF]
, 1985 Poly(α-l-glutamic acid) (PGA) was grafted with amino acid and oligopeptide spacers up to 5 amino acids with the use of N,N'-carbonyldiimidazole and 2,3-dihydro-1,2-benz-isothiazole-3-on-1, 1-dioxide (saccharin) as an additive, and these polypeptides were
Eenink, M.J.D. +5 more
core +2 more sources
Utility of patient-derived lymphoblastoid cell lines as an ex vivo capecitabine sensitivity prediction model for breast cancer patients. [PDF]
, 2016 Capecitabine is commonly used in treating breast cancer; however, therapeutic response varies among patients and there is no clinically validated model to predict individual outcomes.
Abramson, Vandana +11 more
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PLoS ONE, 2017 Anthracyclines are chemotherapeutic drugs known to induce heart failure in a dose-dependent manner. Mechanisms involved in anthracycline cardiotoxicity are an area of relevant investigation.
Yasuhiro Ichikawa +8 more
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Bioactive Materials, 2017 Daunorubicin hydrochloride is a cell-cycle non-specific antitumor drug with a high therapeutic effect. The present study outlines the fabrication of daunorubicin hydrochloride-loaded poly (ε-caprolactone) (PCL) fibrous membranes by melt electrospinning ...
He Lian, Zhaoxu Meng
doaj +1 more source
Synthesis of nine safrole derivatives and their antiproliferative activity towards human cancer cells [PDF]
, 2010 Indexación: ScieloSafrole from sassafras oil (Ocoteapretiosa Mez., Lauraceae), is an abundant natural product showing interesting functionality and chemical structure.
Carrasco Altamirano, Héctor +5 more
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BRD4 associates with p53 in DNMT3A-mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ1 [PDF]
, 2013 The bromodomain and extra terminal (BET) family protein bromodomain containing protein 4 (BRD4) is an epigenetic regulator recently identified as a therapeutic target for several hematological cancers, notably mixed lineage leukemia-fusion acute myeloid ...
Bastow, Sarah +3 more
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Altered Pharmacokinetics of Daunorubicin in Rats with CCl4-Induced Hepatic Injury
Journal of Pharmacy & Pharmaceutical Sciences, 2007 PURPOSE. The effect of CCl4-induced experimental hepatic injury (CCl4-EHI) on the pharmacokinetics of daunorubicin was investigated systemically in rats, in an attempt to elucidate the major determinants of the effect of CCl4-EHI on the pharmacokinetics ...
Min-Koo Choi +4 more
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