Results 11 to 20 of about 53,590 (235)

Casein-Based Nanoparticles: A Potential Tool for the Delivery of Daunorubicin in Acute Lymphocytic Leukemia

Pharmaceutics, 2023
The aim of this study was to develop casein-based nanoscale carriers as a potential delivery system for daunorubicin, as a pH-responsive targeting tool for acute lymphocytic leukemia.
Nikolay Zahariev, Milena Draganova, Plamen Zagorchev, Bissera Pilicheva   +3 more
doaj   +1 more source

Oxaliplatin combined with daunorubicin induces apoptosis of colon cancer cell line HT-29 [PDF]

Jichu yixue yu linchuang, 2020
Objective To study the mechanism of oxaliplatin combined with daunorubicin on the apoptosis of colon cancer cells. Methods Colon cancer cells HT-29 were incubated with different concentrations of oxaliplatin and daunorubicin respectively, MTT assay was ...
TIAN Chun-yang, LIU Xiao-zheng, FAN Jun-chao
doaj  

Optimizing survival outcomes with post-remission therapy in acute myeloid leukemia. [PDF]

, 2019
Optimization of post-remission therapies to maintain complete remission and prevent relapse is a major challenge in treating patients with acute myeloid leukemia (AML).
Chan, Steven M, Daver, Naval G, Jonas, Brian A, Medeiros, Bruno C, Pollyea, Daniel A   +4 more
core   +1 more source

Nano-hole induction by nanodiamond and nanoplatinum liquid, DPV576, reverses multidrug resistance in human myeloid leukemia (HL60/AR). [PDF]

, 2013
Recently nanoparticles have been extensively studied and have proven to be a promising candidate for cancer treatment and diagnosis. In the current study, we examined the chemo-sensitizing activity of a mixture of nanodiamond (ND) and nanoplatinum (NP ...
Ghoneum, Alia, Gimzewski, James, Sharma, Shivani   +2 more
core   +2 more sources

Potential effects of pomegranate on lipid peroxidation and pro-inflammatory changes in daunorubicin-induced cardiotoxicity in rats

International Journal of Preventive Medicine, 2016
Background: Daunorubicin-induced acute cardiotoxicity caused by oxidative stress and free radical formation. Pomegranate possessed a significant in vitro free radical scavenging activity.
Hayder M Al-Kuraishy, Ali I Al-Gareeb
doaj   +1 more source

Alternating electric fields can improve chemotherapy treatment efficacy in blood cancer cell U937 (non-adherent cells)

BMC Cancer, 2023
Background Recent achievements in cancer therapy are the use of alternating electrical fields at intermediate frequencies (100–300 kHz) and low intensities (1–3 V/cm), which specifically target cell proliferation while affecting different cellular ...
Elham Homami, Bahram Goliaei, Seyed Peyman Shariatpanahi, Zahra Habibi-Kelishomi   +3 more
doaj   +1 more source

NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival [PDF]

, 2014
Transcription factor NRF2 is an important regulator of oxidative stress. It is involved in cancer progression, and has abnormal constitutive expression in acute myeloid leukaemia (AML).
A Ooi, AG Ooi, BN Chorley, BT Kvinlaug, C Luna, CR Zhao, D J MacEwan, E Estey, E Surdziel, F Kong, G Tan, GM DeNicola, H Wang, H Zhang, I Spinello, J Alam, J Gong, J Winter, JE Anderson, JJ Tsai, JJ Zhao, JN Gong, K M Bowles, K Okamoto, L Zaitseva, L Zaitseva, M Bousquet, M Bousquet, MB Sporn, MY Murray, N Hanada, N M Shah, P Moi, PA Konstantinopoulos, R Garzon, R Garzon, R Garzon, R Venugopal, S A Rushworth, S Liu, SA Rushworth, SA Rushworth, SA Rushworth, TWP Devling, W Blum, Y Wang, YR Kim   +46 more
core   +1 more source

Identification of Bruton's tyrosine kinase as a therapeutic target in acute myeloid leukemia [PDF]

, 2014
Bruton's tyrosine kinase (BTK) is a cytoplasmic protein found in all hematopoietic cell lineages except for T cells. BTK mediates signalling downstream of a number of receptors.
Advani, Alam, Ashino, Baba, Bendall, Billottet, Burger, Burger, Byrd, Chang, Cordle, Dasmahapatra, David J. MacEwan, de Weers, Dos Santos, Doyle, Fiedler, Gallay, Grandage, Gu, Guzman, Hahn, Herman, Herrmann, Honda, Honigberg, Horwood, Ishii, Juliusson, Kawakami, Kim, Kojima, Kristian M. Bowles, Kvinlaug, Lyubov Zaitseva, Megan Y. Murray, Min, Mohamed, Nanri, Park, Quek, Renneville, Rushworth, Rushworth, Rushworth, Shinners, Sivina, Spiekermann, Stuart A. Rushworth, Sujobert, Tai, Tamburini, Tomasson, Tsukada, Vellenga, Venkataraman, Vetrie, Welch, Westermann, Zaitseva   +59 more
core   +1 more source

Dicarba-closo-dodecarborane-containing half-sandwich complexes of ruthenium, osmium, rhodium and iridium : biological relevance and synthetic strategies [PDF]

, 2012
This review describes how the incorporation of dicarba-closo-dodecarboranes into half-sandwich complexes of ruthenium, osmium, rhodium and iridium might lead to the development of a new class of compounds with applications in medicine. Such a combination
Barry, Nicolas P. E., Sadler, P. J.
core   +1 more source

The Study on Electrochemical Behaviors of the Interactions between Daunorubicin Hydrochloride and BSA

Nano Biomedicine and Engineering, 2010
The Electrochemical behaviors of Daunorubicin hydrochloride, and the interactions between Daunorubicin hydrochloride and BSA, were studied in this paper, with Linear sweep voltammetry and Cyclic voltammety methods.
Jie Liu, Bo Zhang
doaj   +1 more source