Impact of IFN lambda 3/4 single nucleotide polymorphisms on the cytomegalovirus reactivation in autologous stem cell transplant patients [PDF]
, 2018 Cytomegalovirus (CMV) infection represents one of the main cause mortality after Stem Cell Transplantation. Recently, a protective effect of the T allele of rs12979860 IL28B Single Nucleotide Polymorphisms (SNPs) against CMV infection in the allogenic ...
Angeletti, S +13 more
core +1 more source
Novel formulation of cytarabine and daunorubicin: A new hope in AML treatment
South Asian Journal of Cancer, 2015 Acute myeloid leukemia (AML) treatment has always been a challenge to the treating physician. Continuous efforts are being made to improve treatment outcomes in AML. CPX-351 is a pharmacologic advancement in this direction.
Lalit S Raut
doaj +1 more source
Mantle Zone Cell Lymphomas. New Opportunities for Diagnosis and Treatment (Epidemiological Research)
Креативная хирургия и онкология, 2020 Introduction. Mantle cell lymphoma is a rare type of B-cell non-Hodgkin lymphoma. According to statistics the incidence of this disorder amounts to 2-3 per 100,000 people; this is about 6% of all non-Hodgkin lymphomas.
E. I. Kankumasheva +1 more
doaj +1 more source
Physiological and histological effects of apigenin and luteolin on Cytarabine injected rats
مجلة بغداد للعلومThe present study was undertaken to study the effect of apigenin and luteolin on physiological and histological changes in rats treated with cytarabine drugs.
Ghada A. Taqa, Omar N. Sultan
doaj +1 more source
Drug Delivery, 2020 A sodium N-lauryl amino acids (shortly silk sericin surfactant, SSS) is synthesized with lauryl chloride and sericin amino acids recovered from silk industrial waste. The purpose of this study is to explore whether the sericin surfactant can be used as a
Meng Zhang +3 more
doaj +1 more source
Inhibition of histone deacetylases 1 and 6 enhances cytarabine-induced apoptosis in pediatric acute myeloid leukemia cells. [PDF]
PLoS ONE, 2011 BACKGROUND: Pediatric acute myeloid leukemia (AML) remains a challenging disease to treat even with intensified cytarabine-based chemotherapy. Histone deacetylases (HDACs) have been reported to be promising therapeutic targets for treating AML.
Xuelian Xu +5 more
doaj +1 more source
Can pharmacogenetics impact the therapeutic effect of cytarabine and anthracyclines in adult acute myeloid leukaemia patients?: A Serbian experience [PDF]
Journal of Medical BiochemistryBackground: Cytarabine-anthracycline-based induction chemotherapy remains the standard of care for remission induction among patients with newly diagnosed acute myeloid leukaemia (AML).
Pravdić Zlatko +12 more
doaj +1 more source
Cancer Medicine, 2023 Objective We aimed to retrospectively discern the heterogeneity of outcomes from clinicopathological characteristics and next‐generation sequencing (NGS) data in adult patients with NPM1‐mutated (NPM1mut) acute myeloid leukemia (AML) induced with ...
Biao Wang +4 more
doaj +1 more source
Developmental Disorders in Children Recently Diagnosed With Cancer
Pediatric Blood &Cancer, EarlyView.ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag +5 more
wiley +1 more source
Gilteritinib in an Isolated CNS Recurrence of FLT3-ITD Positive AML. [PDF]
Clin Case RepTime course showing changes in cell count and FLT3‐ITD ratio in cerebrospinal fluid (CSF) from diagnosis through treatment. ABSTRACT Central nervous system (CNS) involvement in adult acute myeloid leukemia (AML) is uncommon and more frequently observed at relapse than at initial presentation.
Silva-Bermudez LS +8 more
europepmc +2 more sources