Results 31 to 40 of about 42,251 (222)

Platelet-derived microparticles enhance Ara-C-induced cell death in acute lymphoblastic leukemia (Nalm-6) [PDF]

BioImpacts
Introduction: The current understanding highlights the intricate relationship between leukemic cells and their microenvironment, emphasizing the significant impact of environmental factors on chemotherapy resistance or sensitivity.
Fariba Nikravesh, Hossein Arezoomand, Roohollah h Mirzaee Khalilabadi, Maryam Nooshadokht, Hajar Mardani Valandani   +4 more
doaj   +1 more source

A novel biocompatible Eu-based coordination polymers of cytarabine anticancer drug: Preparation, luminescence properties and in vitro anticancer activity studies

Frontiers in Chemistry, 2022
In this study, we use cytarabine anticancer drug to synthesize a new rare earth complex with Europium ion. The study work is an attempt to investigate luminescence and biological properties of the Eu-based coordination polymers of cytarabine (Eu-CP-Ara ...
Zhijun Zeng, Huaxiang Shen, Wei Gao, Qifeng Guo, Mengjie Chen, Xiaojun Yan, Hongning Liu, Yanhua Ji   +7 more
doaj   +1 more source

Mantle Zone Cell Lymphomas. New Opportunities for Diagnosis and Treatment (Epidemiological Research)

Креативная хирургия и онкология, 2020
Introduction. Mantle cell lymphoma is a rare type of B-cell non-Hodgkin lymphoma. According to statistics the incidence of this disorder amounts to 2-3 per 100,000 people; this is about 6% of all non-Hodgkin lymphomas.
E. I. Kankumasheva, Ch. Kh. Valiakhmetova   +1 more
doaj   +1 more source

Novel formulation of cytarabine and daunorubicin: A new hope in AML treatment

South Asian Journal of Cancer, 2015
Acute myeloid leukemia (AML) treatment has always been a challenge to the treating physician. Continuous efforts are being made to improve treatment outcomes in AML. CPX-351 is a pharmacologic advancement in this direction.
Lalit S Raut
doaj   +1 more source

Sodium N-lauryl amino acids derived from silk protein can form catanionic aggregates with cytarabine as novel anti-tumor drug delivery systems

Drug Delivery, 2020
A sodium N-lauryl amino acids (shortly silk sericin surfactant, SSS) is synthesized with lauryl chloride and sericin amino acids recovered from silk industrial waste. The purpose of this study is to explore whether the sericin surfactant can be used as a
Meng Zhang, Shu-Xiang Zhao, Biao Ding, Yu-Qing Zhang   +3 more
doaj   +1 more source

Physiological and histological effects of apigenin and luteolin on Cytarabine injected rats

مجلة بغداد للعلوم
         The present study was undertaken to study the effect of apigenin and luteolin on physiological and histological changes in rats treated with cytarabine drugs.
Ghada A. Taqa, Omar N. Sultan
doaj   +1 more source

Can pharmacogenetics impact the therapeutic effect of cytarabine and anthracyclines in adult acute myeloid leukaemia patients?: A Serbian experience [PDF]

Journal of Medical Biochemistry
Background: Cytarabine-anthracycline-based induction chemotherapy remains the standard of care for remission induction among patients with newly diagnosed acute myeloid leukaemia (AML).
Pravdić Zlatko, Suvajdžić-Vuković Nada, Virijević Marijana, Mitrović Mirjana, Pantić Nikola, Sabljić Nikica, Pavlović Đorđe, Marjanović Irena, Bukumirić Zoran, Vidović Ana, Jaković Ljubomir, Pavlović Sonja, Gašić Vladimir   +12 more
doaj   +1 more source

Treatment of acute erythroleukaemia with high‐dose cytarabine in a cat with feline leukaemia virus infection

Veterinary Medicine and Science, 2022
Erythroleukaemia is a malignant neoplasm of the erythroid lineage that rarely occurs in cats. It is associated with the feline leukaemia virus (FeLV), and owing to the poor prognosis, treatment is rarely reported.
Da Sol Park, Jongbok Lee, Kun‐Ho Song, Kyoung Won Seo   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Specific KIR-HLA genotypes predict outcomes in refractory or relapsed primary central nervous system lymphoma

Hematology, 2023
Introduction An effective salvage regimen for the reinduction of remission is lacking for refractory or relapsed primary central nervous system lymphoma (r/r PCNSL).
Zhiguang Lin, Huiwen Xu, Jingjing Ma, Yan Ma, Qing Li, Hui Kang, Mengxue Zhang, Bobin Chen   +7 more
doaj   +1 more source