Results 121 to 130 of about 30,296 (276)

APOBEC3G encapsidation into HIV-1 virions: which RNA is it?

Retrovirology, 2008
APOBEC3G is a cytidine deaminase with potent antiviral activity. The protein deaminates single-stranded DNA but is known to bind cellular and viral RNAs.
Khan Mohammad A, Strebel Klaus
doaj   +1 more source

Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery

Nature Communications, 2017
Third-generation base editors consist of a catalytically disabled Cas9 fused to a cytidine deaminase and a base excision repair inhibitor, enabling efficient, precise editing of individual base pairs in DNA.
Holly A. Rees, Alexis C. Komor, Wei-Hsi Yeh, Joana Caetano-Lopes, Matthew Warman, Albert S. B. Edge, David R. Liu   +6 more
doaj   +1 more source

Supplementary Figures and Tables 1-3 from Activation-Induced Cytidine Deaminase Accelerates Clonal Evolution in <i>BCR-ABL1</i>–Driven B-Cell Lineage Acute Lymphoblastic Leukemia

, 2023
Tanja A. Grüber, Mi Sook Chang, Richard Sposto, Markus Müschen   +3 more
openalex   +2 more sources

The SV40 virus enhancer functions as a somatic hypermutation-targeting element with potential tumorigenic activity

Tumour Virus Research
Simian virus 40 (SV40) is a monkey virus with tumorigenic potential in rodents and is associated with several types of human cancers, including lymphomas.
Filip Šenigl, Anni I. Soikkeli, Salomé Prost, David G. Schatz, Martina Slavková, Jiří Hejnar, Jukka Alinikula   +6 more
doaj   +1 more source

Determinants of Specificity for the Trypanosoma brucei A to I tRNA Editing Deaminase [PDF]

, 2008
Trypanosomatids are responsible for causing illness and death among millions of humans and animals worldwide. Two main genera of these unicellular flagellated parasites are Trypanosoma, which cause African sleeping sickness and Chagas disease, and ...
Tseng, Ashlie
core  

Supplementary Table S1 from Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations

, 2023
Yugo Sawai, Yuzo Kodama, Takahiro Shimizu, Yuji Ota, Takahisa Maruno, Yuji Eso, Akira Kurita, Masahiro Shiokawa, Yoshihisa Tsuji, Norimitsu Uza, Yuko Matsumoto, Toshihiko Masui, Shinji Üemoto, Hiroyuki Marusawa, Tsutomu Chiba   +14 more
openalex   +1 more source

Activation-induced cytidine deaminase deficiency causes organ-specific autoimmune disease.

PLoS ONE, 2008
Activation-induced cytidine deaminase (AID) expressed by germinal center B cells is a central regulator of somatic hypermutation (SHM) and class switch recombination (CSR).
Koji Hase, Daisuke Takahashi, Masashi Ebisawa, Sayaka Kawano, Kikuji Itoh, Hiroshi Ohno   +5 more
doaj   +1 more source

Construction of Mycobacterium tuberculosis cdd knockout and evaluation of invasion and growth in macrophages

Memorias do Instituto Oswaldo Cruz
Cytidine deaminase (MtCDA), encoded by cdd gene (Rv3315c), is the only enzyme identified in nucleotide biosynthesis pathway of Mycobacterium tuberculosis that is able to recycle cytidine and deoxycytidine. An M.
Anne Drumond Villela, Valnês S Rodrigues-Junior, Antônio Frederico Michel Pinto, Virgínia Carla de Almeida Falcão, Zilpa Adriana Sánchez-Quitian, Paula Eichler, Cristiano Valim Bizarro, Luiz Augusto Basso, Diógenes Santiago Santos   +8 more
doaj   +1 more source

B cell distribution and activation-induced cytidine deaminase expression in rheumatoid synovitis: clinical and bio-molecular correlates [PDF]

, 2011
Serena Bugatti, Antonio Manzo, B. Vitolo, Chiara Fusetti, F. Humby, Roberto Caporali, C. Pitzalis, Carlomaurizio Montecucco   +7 more
openalex   +1 more source

Association of Cytidine Deaminase Polymorphism with Capecitabine Effectiveness in Breast Cancer Patients. [PDF]

Asian Pac J Cancer Prev, 2023
Aldeen Majeed AA, Salih Sahib A, Shakir Mahmood H, Kadhim Mohsin K, Fadhl Abbas R.   +4 more
europepmc   +1 more source