Plasmodium Falciparum-infected Erythrocytes Adhere to Class A Scavenger Receptor, SR-A [PDF]
, 2013 Severe falciparum malaria such as cerebral malaria and severe anemia is leading causes of morbidity and mortality. Plasmodium falciparum-infected red blood cells (pRBC) adhere to the endothelial cells via receptors expressed on the surface of the ...
Hatabu, Toshimitsu
core
Molecular Microbiology, Volume 121, Issue 3, Page 431-452, March 2024.Proximity‐dependent biotin identification using the egress‐related proteins G377, MDV1, and PPLP2 as bait was performed to identify additional components of the OBs and PPLP2‐positive egress vesicles. The analyses revealed multiple hits for each bait protein and subsequent colocalization experiments showed OB localization for two proteins, an ...
Juliane Sassmannshausen +9 more
wiley +1 more source
Aptamer Technology: Adjunct Therapy for Malaria
Biomedicines, 2017 Malaria is a life-threatening parasitic infection occurring in the endemic areas, primarily in children under the age of five, pregnant women, and patients with human immunodeficiency virus and acquired immunodeficiency syndrome (HIV)/(AIDS) as well as ...
Nik Abdul Aziz Nik Kamarudin +2 more
doaj +1 more source
A role for fetal hemoglobin and maternal immune IgG in infant resistance to Plasmodium falciparum malaria. [PDF]
PLoS ONE, 2011 In Africa, infant susceptibility to Plasmodium falciparum malaria increases substantially as fetal hemoglobin (HbF) and maternal immune IgG disappear from circulation.
Chanaki Amaratunga +7 more
doaj +1 more source
Health Concerns in Cambodia Compounded by Historical and Rural Setbacks [PDF]
, 2020 Cambodia is a country in the Greater Mekong Subregion of Southeast Asia. The Khmer Rouge genocide in the mid 1970s produced significant setbacks in the nation’s healthcare system.
DeHart, Ciera
core +1 more source
Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF. [PDF]
, 2011 Plasmodium falciparum malaria is a major cause of morbidity and mortality in African children, and factors that determine the development of uncomplicated (UM) versus cerebral malaria (CM) are not fully understood.
Wassmer, Samuel Crocodile +5 more
core +3 more sources
Clinical &Translational Immunology, Volume 13, Issue 11, 2024.Natural killer (NK) cells make important contributions to anti‐malarial immunity through antibody‐dependent cellular cytotoxicity (ADCC), but the role of different components of this pathway in promoting NK cell activation remains unclear. We compared the functions and phenotypes of NK cells from malaria‐exposed and malaria‐naive donors, and then ...
Stephen Tukwasibwe +22 more
wiley +1 more source
DYNAMIC DETERMINANTS OF THE CYTOADHERENCE OF PLASMODIUM FALCIPARUM–INFECTED ERYTHROCYTES
The American Journal of Tropical Medicine and Hygiene, 2005 thologists also observed that the process was not uniform among the vital organs, noting particularly the “accumulation in the cerebral vessels of red blood corpuscles loaded with amoebae.” The result of this pathologic process was described as “mechanical alterations in the circulation”; or, in other words, a traffic jam.
openaire +4 more sources
Population Pharmacokinetics and Pharmacodynamics of Artemether and Lumefantrine During Combination Treatment in Children with Uncomplicated Falciparum Malaria in Tanzania. [PDF]
, 2010 The combination of artemether (ARM) and lumefantrine is currently the first-line treatment of uncomplicated falciparum malaria in mainland Tanzania. While the exposure to lumefantrine has been associated with the probability of adequate clinical and ...
Annerberg, Anna +10 more
core +4 more sources
Dynamic association of PfEMP1 and KAHRP in knobs mediates cytoadherence during Plasmodium invasion
Scientific Reports, 2015 Plasmodium falciparum infected erythrocytes display membrane knobs that are essential for their adherence to vascular endothelia and for prevention of clearance by the spleen.
A. Ganguly +3 more
semanticscholar +1 more source