Results 131 to 140 of about 7,415 (242)

Host cell deformability is linked to transmission in the human malaria parasite Plasmodium falciparum [PDF]

, 2012
available in PMC 2013 July 01.Gametocyte maturation in Plasmodium falciparum is a critical step in the transmission of malaria. While the majority of parasites proliferate asexually in red blood cells, a small fraction of parasites undergo sexual ...
Bachmann, Buchholz, Cokelet, Dao, David, Dearnley, Deplaine, Diez-Silva, Esposito, Fung, Glenister, Gruring, Handayani, Hanssen, Hawking, Hayward, Krause, Maier, Mills, Mills, Murray, Nash, Park, Peng, Rogers, Shaner, Silvestrini, Silvestrini, Sinden, Smalley, Spielmann, Suresh, Thomson, Trager, Waugh, Wu   +35 more
core   +1 more source

Neuregulin-1 attenuates mortality associated with experimental cerebral malaria. [PDF]

, 2014
BackgroundCerebral Malaria (CM) is a diffuse encephalopathy caused by Plasmodium falciparum infection. Despite availability of antimalarial drugs, CM-associated mortality remains high at approximately 30% and a subset of survivors develop neurological ...
Anderson, Leonard, Ford, Byron D, Liu, Mingli, Patrickson, John, Pitts, Sidney, Solomon, Wesley, Stiles, Jonathan K, Wilson, Nana O   +7 more
core   +2 more sources

Targeted Disruption of a Ring-infected Erythrocyte Surface Antigen (RESA)-like Export Protein Gene in Plasmodium falciparum Confers Stable Chondroitin 4-Sulfate Cytoadherence Capacity*

Journal of Biological Chemistry, 2014
Background: Factors that influence the cytoadherence property of P. falciparum are not completely understood. Results: Targeted disruption of the gene that encodes a RESA-like protein in P. falciparum results in stable and increased chondroitin 4-sulfate-
Suchi Goel, Arivalagan Muthusamy, J. Miao, L. Cui, A. Salanti, E. Winzeler, D. Gowda   +6 more
semanticscholar   +1 more source

Structural analysis of P. falciparum KAHRP and PfEMP1 complexes with host erythrocyte spectrin suggests a model for cytoadherent knob protrusions.

PLoS Pathogens, 2017
Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) and Knob-associated Histidine-rich Protein (KAHRP) are directly linked to malaria pathology. PfEMP1 and KAHRP cluster on protrusions (knobs) on the P.
Erin E Cutts, Niklas Laasch, Dirk M Reiter, Raphael Trenker, Leanne M Slater, Phillip J Stansfeld, Ioannis Vakonakis   +6 more
doaj   +1 more source

The role of PHIST proteins in cytoadherence of P.falciparum

, 2015
Plasmodium falciparum, the causative agent of malaria, is responsible for over half a million deaths each year and approximately 50% of the world population lives in malaria endemic areas. Despite strategies to reduce the burden of infection like transmission control and development of drugs and vaccines, malaria remains a major public health concern.
openaire   +3 more sources

Alteration in cytoadherence and rosetting of Plasmodium falciparum- infected thalassemic red blood cells [PDF]

, 1993
Rachanee Udomsangpetch, Thanasak Sueblinvong, Kovit Pattanapanyasat, A Dharmkrong-at, Aranya Kittikalayawong, H K Webster   +5 more
openalex   +1 more source

Var transcription profiling of Plasmodium falciparum 3D7: assignment of cytoadherent phenotypes to dominant transcripts

Malaria Journal, 2008
Background Cytoadherence of Plasmodium falciparum-infected red blood cells is mediated by var gene-encoded P. falciparum erythrocyte membrane protein-1 and host receptor preference depends in most cases on which of the 50–60 var genes per genome is ...
Wunderlich Gerhard, Albrecht Letusa, Gölnitz Uta   +2 more
doaj   +1 more source

Platelet activation and inhibition of malarial cytoadherence by the anti-CD36 IgM monoclonal antibody NL07 [PDF]

, 1993
Massimo Alessio, NJ Greco, Luca Primo, Dario Ghigo, Amalia Bosìa, NN Tandon, CF Ockenhouse, GA Jamieson, Fabio Malavasi   +8 more
openalex   +1 more source

Sulfated polyanions inhibit invasion of erythrocytes by plasmodial merozoites and cytoadherence of endothelial cells to parasitized erythrocytes [PDF]

, 1996
Lihua Xiao, Chunfu Yang, P S Patterson, Venkatachalam Udhayakumar, Altaf A. Lal   +4 more
openalex   +1 more source

Plasmodium vivax adherence to placental glycosaminoglycans.

PLoS ONE, 2012
BackgroundPlasmodium vivax infections seldom kill directly but do cause indirect mortality by reducing birth weight and causing abortion. Cytoadherence and sequestration in the microvasculature are central to the pathogenesis of severe Plasmodium ...
Kesinee Chotivanich, Rachanee Udomsangpetch, Rossarin Suwanarusk, Sasithon Pukrittayakamee, Polrat Wilairatana, James G Beeson, Nicholas P J Day, Nicholas J White   +7 more
doaj   +1 more source