Results 71 to 80 of about 6,252 (195)

Association of severe malaria outcomes with platelet-mediated clumping and adhesion to a novel host receptor. [PDF]

open access: yesPLoS ONE, 2011
IntroductionSevere malaria has been attributed partly to the sequestration of Plasmodium falciparum-infected erythrocytes (IEs) in the microvasculature of vital host organs. Identification of P.
Alfredo Mayor   +11 more
doaj   +1 more source

ICAM-1 is a key receptor mediating cytoadherence and pathology in the Plasmodium chabaudi malaria model

open access: yesMalaria Journal, 2017
Background Parasite cytoadherence within the microvasculature of tissues and organs of infected individuals is implicated in the pathogenesis of several malaria syndromes. Multiple host receptors may mediate sequestration.
Deirdre A. Cunningham   +8 more
doaj   +1 more source

Ex-vivo cytoadherence phenotypes of Plasmodium falciparum strains from Malian children with hemoglobins A, S, and C. [PDF]

open access: yesPLoS ONE, 2014
Sickle hemoglobin (Hb) S and HbC may protect against malaria by reducing the expression of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) on the surface of parasitized red blood cells (RBCs), thereby weakening their cytoadherence to ...
Jeanette T Beaudry   +7 more
doaj   +1 more source

Plasmodium Falciparum-infected Erythrocytes Adhere to Class A Scavenger Receptor, SR-A [PDF]

open access: yes, 2013
Severe falciparum malaria such as cerebral malaria and severe anemia is leading causes of morbidity and mortality. Plasmodium falciparum-infected red blood cells (pRBC) adhere to the endothelial cells via receptors expressed on the surface of the ...
Hatabu, Toshimitsu
core  

Comparative 1D Blue-Native electrophoresis analysis of Plasmodium falciparum and human proteins associated with cytoadherence. [PDF]

open access: yes, 2018
BACKGROUND To understand more about changes to the molecular components that occur when host endothelium interacts with Plasmodium falciparum-infected erythrocytes, a combined technique of protein separation (1D Blue-Native electrophoresis) and mass ...
Al-Harthi, Saeed   +3 more
core   +6 more sources

Case Report: Concurrent Babesiosis and GCA/PMR

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 3, March 2025.
Babesiosis is a tick‐transmitted infectious disease caused by parasites of the genus Babesia. Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are common interrelated inflammatory disorders. This report presents the first case of concurrent babesiosis and GCA/PMR.
Xiaolin Wang   +4 more
wiley   +1 more source

Virulence and the immune response in malaria

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
Many factors determine the virulence of a malaria infection. These include host innate resistance mechanisms and, with Plasmodium falciparum, the ability to cytoadhere to endothelial cells, form rosetts, and induce release of cytokines.
G. A. T. Targett
doaj   +1 more source

Molecular Dynamics Simulation of Soft Grains: Malaria-Infected Red Blood Cells Motion within Obstructed 2-D Capillary Vessel

open access: yes, 2013
Molecular dynamics has been widely used to numerically solve equation of motion of classical many-particle system. It can be used to simulate many systems including biophysics, whose complexity level is determined by the involved elements.
Haris, Luman   +3 more
core   +1 more source

Plasma Soluble Progenitor Cell Receptors as Biomarkers for Severe Anemia Among Malaria‐Infected Pediatrics: A Prospective Study in Ghana

open access: yesHealth Science Reports, Volume 8, Issue 2, February 2025.
ABSTRACT Background Soluble forms of progenitor cell receptors may be implicated in the delayed erythropoietic response during severe anemia. In this study, plasma levels of soluble erythropoietin receptor (sEPO‐R) and soluble granulocyte, macrophage‐colony stimulating factor receptor (sGM‐CSFR) were assessed in Plasmodium falciparum‐infected children ...
Charles Nkansah   +25 more
wiley   +1 more source

A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum–infected erythrocytes [PDF]

open access: yesBlood, 2016
Key Points Plasmodium falciparum–generated cytoadherent knobs on infected erythrocytes contain a spiral framework linked to the red cell cytoskeleton. The findings suggest a structural basis for transmission of shear forces in adhesion of infected cells.
Watermeyer, Jean M.   +8 more
openaire   +5 more sources

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