Results 81 to 90 of about 7,415 (242)

Molecular Dynamics Simulation of Soft Grains: Malaria-Infected Red Blood Cells Motion within Obstructed 2-D Capillary Vessel

, 2013
Molecular dynamics has been widely used to numerically solve equation of motion of classical many-particle system. It can be used to simulate many systems including biophysics, whose complexity level is determined by the involved elements.
Haris, Luman, Haryanto, Freddy, Khotimah, Siti Nurul, Viridi, Sparisoma   +3 more
core   +1 more source

Antibody recognition of Plasmodium falciparum infected red blood cells by symptomatic and asymptomatic individuals in the Brazilian Amazon

Memorias do Instituto Oswaldo Cruz, 2014
In the Amazon Region, there is a virtual absence of severe malaria and few fatal cases of naturally occurring Plasmodium falciparum infections; this presents an intriguing and underexplored area of research.
Alessandra Sampaio Bassi Fratus, Fernanda Janku Cabral, Wesley Luzetti Fotoran, Márcia Melo Medeiros, Bianca Cechetto Carlos, Rosimeire dalla Martha, Luiz Hildebrando Pereira da Silva, Stefanie Costa Pinto Lopes, Fabio Trindade Maranhão Costa, Gerhard Wunderlich   +9 more
doaj   +1 more source

Plasmodium falciparum proteins involved in cytoadherence of infected erythrocytes to chemokine CX3CL1

Scientific Reports, 2016
Malaria caused by Plasmodium falciparum is associated with cytoadherence of infected red blood cells (iRBC) to endothelial cells. Numerous host molecules have been involved in cytoadherence, including the adhesive chemokine CX3CL1. Most of the identified
P. Hermand, L. Cicéron, C. Pionneau, C. Vaquero, C. Combadière, P. Deterre   +5 more
semanticscholar   +1 more source

Microarray Analysis of PBMC after Plasmodium falciparum Infection: Molecular Insights into Disease Pathogenesis [PDF]

, 2011
Our laboratory’s previous microarray analysis of subjects with Plasmodium falciparum revealed up-regulation of Toll-like receptor, NF-kB, TNF-α, IFN-γ, IL-1β, p38 MAPK, and MHC molecules.
Alan Scott, Anne Jedlicka, August Louis Bourgeois, Nathan Wolfe, Sher Singh, Wan-Chung(Wan-Jiung) Hu   +5 more
core   +1 more source

Antimalarial Drugs Reduce Cytoadherence and Rosetting of Plasmodium falciparum [PDF]

Journal of Infectious Diseases, 1996
The in vivo and in vitro effects of antimalarials on cytoadherence and rosette formation were studied in 17 patients with severe and 46 with uncomplicated falciparum malaria. Cytoadherence was increased in severe malaria (P50% inhibition of both cytoadherence and rosetting in vivo and in vitro within 2 hr of drug exposure. Exposure to quinine for > or =
Udomsangpetch, R, Pipitaporn, B, Krishna, S, Angus, B, Pukrittayakamee, S, Bates, I, Suputtamongkol, Y, Kyle, D, White, N   +8 more
openaire   +4 more sources

High-throughput and label-free blood-on-a-chip for malaria diagnosis [PDF]

, 2019
The malaria parasite Plasmodium falciparum (Pf) changes the structure and mechanical properties of red blood cells (RBCs). These changes decrease deformability and increase cytoadherence of Pf-infected RBCs to the vascular endothelium, eventually leading
Ha, Y.-R, Kang, Y.J, Lee, S.-J.
core   +1 more source

Plasma Soluble Progenitor Cell Receptors as Biomarkers for Severe Anemia Among Malaria‐Infected Pediatrics: A Prospective Study in Ghana

Health Science Reports, Volume 8, Issue 2, February 2025.
ABSTRACT Background Soluble forms of progenitor cell receptors may be implicated in the delayed erythropoietic response during severe anemia. In this study, plasma levels of soluble erythropoietin receptor (sEPO‐R) and soluble granulocyte, macrophage‐colony stimulating factor receptor (sGM‐CSFR) were assessed in Plasmodium falciparum‐infected children ...
Charles Nkansah, Samuel K. Appiah, Felix Osei‐Boakye, Emmanuel Appiah‐Kubi, Gabriel Abbam, Samira Daud, Charles A. Derigubah, Simon B. Bani, Moses Banyeh, Kofi Mensah, Ruby Tater, Jennifer Obeng Mensah, Anne Natornaa, Isaac Adjei, Muniru M. Tanko, Gilbert Amankwaa, Peter K. Selleh, Samuel B. Aboagye, Onwuka K. Chima, Sylvanus M. Kpangkpari, Prince Ottah, Enoch Boadi, Yeduah Quansah, Ejike F. Chukwurah, Boniface N. Ukwah, Victor U. Usanga   +25 more
wiley   +1 more source

Precise Similarity of Many Human Proteins to Proteins of Prokarya [PDF]

, 2007
Proteins originated in early forms of life and have long survived, because they have always been required. Some recognizably similar proteins are found in all sequence comparisons between species, no matter how distant, including prokaryotes and ...
Roy Britten
core   +2 more sources

Monocyte‐derived extracellular vesicles, stimulated by Trypanosoma cruzi, enhance cellular invasion in vitro via activated TGF‐β1

Journal of Extracellular Vesicles, Volume 13, Issue 11, November 2024.
Abstract During cell invasion, large Extracellular Vesicle (lEV) release from host cells was dose‐dependently triggered by Trypanosoma cruzi metacyclic trypomastigotes (Mtr). This lEV release was inhibited when IP3‐mediated Ca2+ exit from the ER and further Ca2+ entry from plasma membrane channels was blocked, but whilst any store‐independent Ca2 ...
Ephraim A. Ansa‐Addo, Paras Pathak, Maria V. McCrossan, Izadora Volpato Rossi, Mahamed Abdullahi, Dan Stratton, Sigrun Lange, Marcel I. Ramirez, Jameel M. Inal   +8 more
wiley   +1 more source

A Plasmodium falciparum S33 proline aminopeptidase is associated with changes in erythrocyte deformability [PDF]

, 2016
Infection with the apicomplexan parasite Plasmodium falciparum is a major cause of morbidity and mortality worldwide. One of the Striking features of this parasite is its ability to remodel and decrease the deformability of host red blood cells, a ...
Brown, Christopher L., da Silva, Fabio L., Dalton, John P., Dixon, Matthew W. A., Gardiner, Donald L., Jones, Malcolm K., Lovas, Erica, Skinner-Adams, Tina S., Stack, Colin M., Taran, Elena, Teuscher, Franka, Tilley, Leann, Trenholme, Katharine R.   +12 more
core   +1 more source