Results 101 to 110 of about 48,300 (266)

Revitalising Aging Oocytes: Echinacoside Restores Mitochondrial Function and Cellular Homeostasis Through Targeting GJA1/SIRT1 Pathway

Cell Proliferation, EarlyView.
ECH protects senescent oocytes by stabilising the cytoskeleton, restoring mitochondrial function, reducing oxidative stress and maintaining cellular homeostasis, primarily through the GJA1/SIRT1 signalling pathway. ABSTRACT As maternal age increases, the decline in oocyte quality emerges as a critical factor contributing to reduced reproductive ...
Liuqing Yang, Xinle Lai, Fangxuan Lin, Nan Shi, Xinya Xu, Heng Wang, Xiaotian Li, Dan Shen, Haimo Qian, Xin Jin, Jiayi Chen, Zhongwei Huang, Xing Duan, Qin Zhang   +13 more
wiley   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, EarlyView.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

Ipriflavone-Loaded Mesoporous Nanospheres with Potential Applications for Periodontal Treatment

Nanomaterials, 2020
The incorporation and effects of hollow mesoporous nanospheres in the system SiO2–CaO (nanoMBGs) containing ipriflavone (IP), a synthetic isoflavone that prevents osteoporosis, were evaluated.
Laura Casarrubios, Natividad Gómez-Cerezo, María José Feito, María Vallet-Regí, Daniel Arcos, María Teresa Portolés   +5 more
doaj   +1 more source

Fusion of isolated myoblast plasma membranes [PDF]

, 1978
Fusion of plasma membranes isolated from myoblasts grown in culture has been investigated. 1. 1. Membrane fusion was specifically dependent on Ca2+ at physiological concentrations. However, at higher concentrations of cations, fusion could be triggered
Ahkong, Batzri, Berl, Berlin, Burwen, Croce, Dahl, Dahl, Dahl, De Camilli, Douglas, Dreifuss, Fairbanks, Gratzl, Gratzl, Gratzl, Hauser, Holtzer, Kalderon, Kantor, Kent, Lawson, Lee, Maeda, Martin, Okada, Okada, Onishi, Orci, Pagano, Papahadjopoulos, Papahadjopoulos, Papahadjopoulos, Papahadjopoulos, Pauli, Peretz, Poole, Poste, Prives, Rash, Reed, Reeves, Sanger, Satir, Schimmel, Schlessinger, Schudt, Schudt, Schudt, Schudt, Shainberg, Shainberg, Van den Bosch, Van den Bosch, Van den Bosch, Vos, Weidekamm, Weidekamm, Yanofsky, Zakai   +59 more
core   +1 more source

Cytochalasin-B-Inducible Nanovesicle Mimics of Natural Extracellular Vesicles That Are Capable of Nucleic Acid Transfer

Micromachines, 2019
Extracellular vesicles provide cell-to-cell communication and have great potential for use as therapeutic carriers. This study was aimed at the development of an extracellular vesicle-based system for nucleic acid delivery.
Anastasiya Oshchepkova, Alexandra Neumestova, Vera Matveeva, Lyudmila Artemyeva, Ksenia Morozova, Elena Kiseleva, Marina Zenkova, Valentin Vlassov   +7 more
doaj   +1 more source

Activation of ADF/cofilin by phosphorylation-regulated Slingshot phosphatase is required for the meiotic spindle assembly in Xenopus laevis oocytes [PDF]

, 2013
We identify Xenopus ADF/cofilin (XAC) and its activator, Slingshot phosphatase (XSSH), as key regulators of actin dynamics essential for spindle microtubule assembly during Xenopus oocyte maturation.
Abe, Hiroshi, De Bock, Pieter-Jan, Fujiki, Saburo, Gevaert, Kris, Iwase, Shohei, Kuchitsu, Miyako, Ono, Shoichiro, Sato, Ryuhei, Tawada, Toshinobu, Yamagishi, Yuka   +9 more
core   +1 more source

Clot formation and resolution properties of platelets during cold storage for 21 days

Transfusion, EarlyView.
Abstract Background Cold storage (2–6°C) preserves the aggregatory and clot formation properties of platelets beyond the standard 7‐day shelf life. Comparatively little is known about the effect of cold storage on clot resolution functions, which are necessary to ensure normal hemostatic balance is maintained.
Janhavi Mahajan, Matthew P. Padula, Denese C. Marks, Lacey Johnson   +3 more
wiley   +1 more source

Reciprocal and dynamic polarization of planar cell polarity core components and myosin

eLife, 2015
The Ciona notochord displays planar cell polarity (PCP), with anterior localization of Prickle (Pk) and Strabismus (Stbm). We report that a myosin is polarized anteriorly in these cells and strongly colocalizes with Stbm.
Erin Newman-Smith, Matthew J Kourakis, Wendy Reeves, Michael Veeman, William C Smith   +4 more
doaj   +1 more source

Regulation of reactivated elongation in lysed cell models of teleost retinal cones by cAMP and calcium. [PDF]

, 1986
Teleost retinal cones elongate in the dark and contract in the light. In isolated retinas of the green sunfish Lepomis cyanellus, cone myoids undergo microtubule-dependent elongation from 5 to 45 micron. We have previously shown that cone contraction can
Ackland, N, BURNSIDE, Beth, Gilson, C
core   +1 more source

Oocyte Enucleation Phase in Mouse Cloning [PDF]

International Journal of Fertility and Sterility, 2007
Abdolhossein Shahverdi, Rahman Fakhery, Azam Dalman   +2 more
doaj   +1 more source